In vitro-in vivo correlations of pulmonary inflammogenicity and genotoxicity of MWCNT

Autor: Emilio Di Ianni, Johanna Samulin Erdem, Peter Møller, Nicklas Mønster Sahlgren, Sarah Søs Poulsen, Kristina Bram Knudsen, Shan Zienolddiny, Anne Thoustrup Saber, Håkan Wallin, Ulla Vogel, Nicklas Raun Jacobsen

Publikováno v: Particle and Fibre Toxicology, Vol 18, Iss 1, Pp 1-16 (2021)

Abstract Background Multi-walled carbon nanotubes (MWCNT) have received attention due to extraordinary properties, resulting in concerns for occupational health and safety. Costs and ethical concerns of animal testing drive a need for in vitro models

Externí odkaz: https://doaj.org/article/0d6a87d0ebdf4881add32020731523b6

Organomodified nanoclays induce less inflammation, acute phase response, and genotoxicity than pristine nanoclays in mice lungs

Autor: Ulla Vogel, Emilio Di Ianni, Nicklas Raun Jacobsen, Per Axel Clausen, Józef Szarek, Alicja Mortensen, Peter Møller, Anne T. Saber

Publikováno v: Di Ianni, E, Møller, P H, Mortensen, A, Szarek, J, Clausen, P A, Saber, A T, Vogel, U B & Jacobsen, N R 2020, ' Organomodified nanoclays induce less inflammation, acute phase response, and genotoxicity than pristine nanoclays in mice lungs ', Nanotoxicology, vol. 14, no. 7, pp. 869-892 . https://doi.org/10.1080/17435390.2020.1771786
Di Ianni, E, Møller, P, Mortensen, A, Szarek, J, Clausen, P A, Saber, A T, Vogel, U & Jacobsen, N R 2020, ' Organomodified nanoclays induce less inflammation, acute phase response, and genotoxicity than pristine nanoclays in mice lungs ', Nanotoxicology, vol. 14, no. 7, pp. 869-892 . https://doi.org/10.1080/17435390.2020.1771786
Nanotoxicology

Surface modification by different quaternary ammonium compounds (QAC) makes nanoclays more compatible with various polymeric matrices, thereby expanding their potential applications. The growing industrial use of nanoclays could potentially pose a he

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb13b574f650e797a16ef2dab156b60
https://doi.org/10.1080/17435390.2020.1771786

Systematic review on primary and secondary genotoxicity of carbon black nanoparticles in mammalian cells and animals

Autor: Emilio, Di Ianni, Nicklas Raun, Jacobsen, Ulla Birgitte, Vogel, Peter, Møller

Publikováno v: Di Ianni, E, Jacobsen, N R, Vogel, U B & Møller, P 2022, ' Systematic review on primary and secondary genotoxicity of carbon black nanoparticles in mammalian cells and animals ', Mutation Research-Reviews, vol. 790, 108441 . https://doi.org/10.1016/j.mrrev.2022.108441
Di Ianni, E, Jacobsen, N R, Vogel, U B & Moller, P 2022, ' Systematic review on primary and secondary genotoxicity of carbon black nanoparticles in mammalian cells and animals ', Mutation Research-Reviews, vol. 790, 108441 . https://doi.org/10.1016/j.mrrev.2022.108441

Carbon black exposure causes oxidative stress, inflammation and genotoxicity. The objective of this systematic review was to assess the contributions of primary (i.e. direct formation of DNA damage) and secondary genotoxicity (i.e., DNA lesions produ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::113f493117ac81c17d2367e1dd266d72
https://orbit.dtu.dk/en/publications/49839111-8dd5-491a-b3bd-bc145e0c9db3

Reactive oxygen species production, genotoxicity and telomere length in FE1-Muta™Mouse lung epithelial cells exposed to carbon nanotubes

Autor: Regitze Sølling Wils, Martin Roursgaard, Emilio Di Ianni, Peter Møller, Nicklas Raun Jacobsen

Carbon nanotubes (CNTs) are fiber-like nanomaterials, which are used in various applications with possible exposure to humans. The genotoxicity and carcinogenic potential of CNTs remain to be fully understood. This study assessed the genotoxicity of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cebf640659068dcac9c9d9f02c58b4d