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of 2
pro vyhledávání: '"Emilija Ruksenaite"'
Autor:
Fiona J. Flett, Emilija Ruksenaite, Lee A. Armstrong, Shipra Bharati, Roberta Carloni, Elizabeth R. Morris, C. Logan Mackay, Heidrun Interthal, Julia M. Richardson
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Human tyrosyl-DNA phosphodiesterase 1 (Tdp1) repairs covalently trapped topoisomerase 1B-DNA complexes and other lesions, and is a target for anticancer drug development. Here the authors use an integrated structural approach to shed light onto the m
Externí odkaz:
https://doaj.org/article/2dff6c27b8244f03bdfbb18f51738a7b
Autor:
Fiona J, Flett, Emilija, Ruksenaite, Lee A, Armstrong, Shipra, Bharati, Roberta, Carloni, Elizabeth R, Morris, C Logan, Mackay, Heidrun, Interthal, Julia M, Richardson
Publikováno v:
Nature Communications
Tyrosyl-DNA phosphodiesterase (Tdp1) is a DNA 3′-end processing enzyme that repairs topoisomerase 1B-induced DNA damage. We use a new tool combining site-specific DNA–protein cross-linking with mass spectrometry to identify Tdp1 interactions with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::48dec214d00824c13c0ed0e3bc8990f6
https://pubmed.ncbi.nlm.nih.gov/29295983
https://pubmed.ncbi.nlm.nih.gov/29295983