Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Emilien Loeuillard"'
Autor:
Vivian Ortiz, Emilien Loeuillard
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 19, Iss 1, Pp 101407- (2025)
Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy, including the two most common liver tumors, hepatocellular carcinoma and cholangiocarcinoma, but their use in the peri-transplantation period is controversial. ICI therapy aims t
Externí odkaz:
https://doaj.org/article/18057bb73eee43848cb4362750e0ff02
Publikováno v:
JHEP Reports, Vol 1, Iss 4, Pp 297-311 (2019)
Summary: Cholangiocarcinoma (CCA) represents a heterogeneous group of epithelial tumours that are classified according to anatomical location as intrahepatic (iCCA), perihilar (pCCA), or distal (dCCA). Although surgical resection and liver transplant
Externí odkaz:
https://doaj.org/article/3019c687195b404d9ca7abb6d4f621df
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 1153-1154 (2021)
Externí odkaz:
https://doaj.org/article/d1c77baf26a54fbf82138f857af8ba68
Autor:
Chloé Melchior, Emilien Loeuillard, Rachel Marion-Letellier, Lionel Nicol, Paul Mulder, Charlène Guerin, Christine Bôle-Feysot, Moutaz Aziz, Pierre Déchelotte, Pierre Vera, Guillaume Savoye, Céline Savoye-Collet
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e100921 (2014)
BACKGROUND: Magnetic resonance colonography (MRC) has been developed to assess inflammatory bowel diseases. We aimed to assess the feasibility of MRC in rats with TNBS-induced chronic colitis and to confront imaging results with fibrosis and stenosin
Externí odkaz:
https://doaj.org/article/edfef9ac75ca4ce28599450a9a012e65
Publikováno v:
Expert Opin Ther Targets
Introduction CCAs are dense and desmoplastic tumors with an abundant tumor microenviroment (TME). The evolving TME is characterized by reciprocal interactions between cancer cells and their environment and is essential in facilitating tumor progressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70997efb2c34c84f42097e6e7fdf3ab7
https://doi.org/10.1080/14728222.2021.2010046
https://doi.org/10.1080/14728222.2021.2010046
Publikováno v:
Clinical Cancer Research. 28:PO032-PO032
Background and Aims: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), a member of TNF superfamily, is predominantly expressed on immune cells. Engagement of TRAIL with its cognate receptor, TRAIL-R (TR), leads to cancer cells apoptosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::163508f864b5990be8f6d716390f8c2c
https://doi.org/10.1158/1557-3265.liverca22-po032
https://doi.org/10.1158/1557-3265.liverca22-po032
Publikováno v:
Cancer Research. 82:1315-1315
Background and Aims: Tumor necrosis factor related apoptosis inducing ligand (TRAIL) is predominantly expressed on immune cells. Although TRAIL biology has garnered considerable attention as a potential anti-cancer strategy, TRAIL agonists have had v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ee7fad4c0b93ae8a524c2e2e0fa0364
https://doi.org/10.1158/1538-7445.am2022-1315
https://doi.org/10.1158/1538-7445.am2022-1315
Autor:
Lin Lei, Haquima El Mourabit, Emilien Loeuillard, Chantal Housset, Sara Lemoinne, Axelle Cadoret
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1864:3688-3696
Portal myofibroblasts (PMF) form a sub-population of highly proliferative and proangiogenic liver myofibroblasts that derive from portal mesenchymal progenitors. Endoplasmic reticulum (ER) stress was previously shown to modulate fibrogenesis, notably
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07461265d3779e831c3755e3591001d
https://doi.org/10.1016/j.bbadis.2018.10.008
https://doi.org/10.1016/j.bbadis.2018.10.008
Autor:
Rondell P. Graham, Caitlin B. Conboy, Daniel R. O'Brien, Yuanhang Liu, Emilien Loeuillard, Rory L. Smoot, Jingchun Yang, Juan Wang, Ying Li, Chen Wang, Kevin D. Pavelko, Sumera Ilyas, Haidong Dong, Eee L.N. Buckarma
Publikováno v:
J Clin Invest
Immune checkpoint blockade (ICB) has revolutionized cancer therapeutics. Desmoplastic malignancies, such as cholangiocarcinoma (CCA), have an abundant tumor immune microenvironment (TIME). However, to date, ICB monotherapy in such malignancies has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1130de14b8ea226587dd0c4b27ae2a08
https://pubmed.ncbi.nlm.nih.gov/32663198
https://pubmed.ncbi.nlm.nih.gov/32663198
Publikováno v:
Cancer Immunology Research. 10:P072-P072
Background and Aims: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is predominantly expressed on immune cells. Although TRAIL biology has garnered considerable interest as a potential anti-cancer strategy, TRAIL agonists have had ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1034a30b9401b5efae9a090ad42a62d
https://doi.org/10.1158/2326-6074.tumimm21-p072
https://doi.org/10.1158/2326-6074.tumimm21-p072