Výsledky vyhledávání - "Emilie d'Aldebert"

Akademický článek

Characterization of Human Colon Organoids From Inflammatory Bowel Disease Patients

Autor: Emilie d’Aldebert, Muriel Quaranta, Morgane Sébert, Delphine Bonnet, Sylvain Kirzin, Guillaume Portier, Jean-Pierre Duffas, Sophie Chabot, Philippe Lluel, Sophie Allart, Audrey Ferrand, Laurent Alric, Claire Racaud-Sultan, Emmanuel Mas, Céline Deraison, Nathalie Vergnolle

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 8 (2020)

Inflammatory Bowel Diseases (IBD) are chronic inflammatory disorders, where epithelial defects drive, at least in part, some of the pathology. We reconstituted human intestinal epithelial organ, by using three-dimension culture of human colon organoi

Externí odkaz: https://doaj.org/article/6b853c08948343d7a4899a9efefe8f72

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Luminal contents from the gut of colicky infants induce visceral hypersensitivity in mice

Autor: Julien Sauser, F. Foata, Sophie Yvon, Bernard Berger, Emmanuel Mas, Clara Lucia Garcia-Rodenas, Helene Eutamene, Emilie d'Aldebert, Gabriela Bergonzelli, V. Theodorou

Publikováno v: Journal of Neurogastroenterology and Motility
Journal of Neurogastroenterology and Motility, Korean Society of Neurogastroenterology and Motility, 2017, 29 (4), ⟨10.1111/nmo.12994⟩

International audience; Background: The pathophysiology of infantile colic is poorly understood, though various studies report gut microbiota dysbiosis in colicky infants. We aimed to test the hypothesis that colic-related dysbiosis is associated wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93d4b1a4a4bf70e15e8a1cb698f352f8
https://hal.inrae.fr/hal-02624758

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PAR2-dependent activation of GSK3 beta regulates the survival of colon stem/progenitor cells

Autor: Emmanuel Mas, Emilie d'Aldebert, Raoudha Mezghani-Jarraya, Bailey Zwarycz, Nathalie Vergnolle, Claire Racaud-Sultan, Nicolas Cenac, Delphine Bonnet, Scott T. Magness, Corinne Rolland, Muriel Quaranta, Laurianne Van Landeghem, Audrey Ferrand, Sokchea Khou, Chrystelle Bonnart, Imen Nasri

Publikováno v: American Journal of Physiology. Gastrointestinal and Liver Physiology 2 (311), G221-G236. (2016)
AJP-Gastrointestinal and Liver Physiology
AJP-Gastrointestinal and Liver Physiology, 2016, 311 (2), pp.G221-G236. ⟨10.1152/ajpgi.00328.2015⟩
AJP-Gastrointestinal and Liver Physiology, American Physiological Society, 2016, 311 (2), pp.G221-G236. ⟨10.1152/ajpgi.00328.2015⟩

Protease-activated receptors PAR1 and PAR2 play an important role in the control of epithelial cell proliferation and migration. However, the survival of normal and tumor intestinal stem/progenitor cells promoted by proinflammatory mediators may be c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26a614ffab0f5fc3bea1c336a4d5f820
http://prodinra.inra.fr/record/386457

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Effects of 1-week sacral nerve stimulation on the rectal intestinal epithelial barrier and neuromuscular transmission in a porcine model

Autor: Nathalie Vergnolle, Guillaume Meurette, Emilie d'Aldebert, Michel Neunlist, M. Provost, Philippe Aubert, E. Duchalais-Dassonneville, Jérémy Brégeon

Publikováno v: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 27(1)

Background Sacral nerve stimulation (SNS) is a validated treatment for fecal incontinence, although the mechanism of action remains unknown. Short-term effects of SNS on the intestinal epithelial barrier (IEB) have been reported previously. The aim o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5b85553b2be5d84568df876c28f721
https://pubmed.ncbi.nlm.nih.gov/25388954

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Bile salts control the antimicrobial peptide cathelicidin through nuclear receptors in the human biliary epithelium

Autor: Raoul Poupon, Dominique Wendum, Marie–Jeanne Biyeyeme Bi Mve, Nicolas Chignard, Laura Fouassier, Christophe Corpechot, Audrey Coilly, Delphine Firrincieli, Emilie d'Aldebert, Chantal Housset, Martine Mergey

Publikováno v: Gastroenterology. 136(4)

Backgrounds & aims Under normal conditions, the biliary tract is a microbial-free environment. The absence of microorganisms has been attributed to various defense mechanisms that include the physicochemical and signaling actions of bile salts. Here,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90630be1f2f839daf268131bd184841
https://pubmed.ncbi.nlm.nih.gov/19236967

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Transient Receptor Potential Vanilloid 4 Activated Inflammatory Signals by Intestinal Epithelial Cells and Colitis in Mice

Autor: Laurent Alric, Laurence Martin, Emilie d'Aldebert, Nathalie Vergnolle, Nicolas Cenac, Janick Selves, Kevin Chapman, Jean-Pierre Vinel, Corinne Rolland, Perrine Rousset

Publikováno v: Gastroenterology. 140:275-285.e3

Background & Aims Ligand-gated calcium channels have been reported to be involved in the pathogenesis of inflammatory bowel disease. One family member, transient receptor potential vanilloid 4 (TRPV4), is activated by arachidonic acid derivatives tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d09c91cd6fee37561620adcd58a05dc4
https://doi.org/10.1053/j.gastro.2010.09.045

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