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pro vyhledávání: '"Emilie Yeonwha Song"'
Publikováno v:
Angewandte Chemie International Edition
The ability of RNA to catalyze RNA ligation is critical to its central role in many prebiotic model scenarios, in particular the copying of information during self-replication. Prebiotically plausible ribozymes formed from short oligonucleotides can
Autor:
Huacan Lin, Eddy I. Jiménez, Ramanarayanan Krishnamurthy, Emilie Yeonwha Song, Hannes Mutschler, Kristian Le Vay
Publikováno v:
Angewandte Chemie (International Ed. in English)
Angewandte Chemie International Edition
Angewandte Chemie International Edition
RNA‐catalyzed RNA ligation is widely believed to be a key reaction for primordial biology. However, since typical chemical routes towards activating RNA substrates are incompatible with ribozyme catalysis, it remains unclear how prebiotic systems g
Autor:
Eddy I. Jiménez, Hannes Mutschler, Emilie Yeonwha Song, Huacan Lin, Kristian Le Vay, Ramanarayanan Krishnamurthy
Publikováno v:
Angewandte Chemie. 133:2988-2993
Publikováno v:
Chemistry, an Asian Journal
Catalysis by nucleic acids is indispensable for extant cellular life, and it is widely accepted that nucleic acid enzymes were crucial for the emergence of primitive life 3.5‐4 billion years ago. However, geochemical conditions on early Earth must