Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Emilie Tresse"'
Autor:
Orla T. Cox, Neil O’Sullivan, Emilie Tresse, Stephanie Ward, Niamh Buckley, Rosemary O’Connor
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The PDZ-LIM domain-containing protein 2 (PDLIM2) regulates cell polarity and the protein stability of key transcription factors in epithelial and hemopoietic cells. We previously reported that PDLIM2 is more highly expressed in Triple Negative Breast
Externí odkaz:
https://doaj.org/article/4035ff74f52a483a9faba202d1a5fca0
Autor:
Elham Jaberi, Emilie Tresse, Kirsten Grønbæk, Joachim Weischenfeldt, Shohreh Issazadeh-Navikas
Publikováno v:
EBioMedicine, Vol 57, Iss , Pp 102868- (2020)
Background: Point mutations and structural variations (SVs) in mitochondrial DNA (mtDNA) contribute to many neurodegenerative diseases. Technical limitations and heteroplasmy, however, have impeded their identification, preventing these changes from
Externí odkaz:
https://doaj.org/article/bd07e6c2fdc94842820b8d8aa555511f
Autor:
Emilie Tresse, Joao N. Duarte, Gisela Jimenez-Duran, Shohreh Issazadeh-Navikas, Oliver Kretz, Desiree Loreth, Tobias Goldmann, Yawei Liu, Erika B Villanueva, Marco Prinz, Patrick Ejlerskov
Publikováno v:
Villanueva, E B, Tresse, E, Liu, Y, Duarte, J N, Jimenez-Duran, G, Ejlerskov, P, Kretz, O, Loreth, D, Goldmann, T, Prinz, M & Issazadeh-Navikas, S 2021, ' Neuronal TNFα, not α-syn, underlies PDD-like disease progression in IFNβ-KO mice ', Annals of Neurology, vol. 90, no. 5, pp. 789-807 . https://doi.org/10.1002/ana.26209
OBJECTIVE: Parkinson's disease (PD) manifests in motor dysfunction, non-motor symptoms, and eventual dementia (PDD). Neuropathological hallmarks include nigrostriatal neurodegeneration, Lewy body (LB) pathology, and neuroinflammation. Alpha-synuclein
Publikováno v:
Cancer Research. 82:2528-2528
PDLIM2 is a PDZ-LIM domain protein expressed in hematopoietic and epithelial cells that regulates the stability of transcription factors including NFΚB, STATs and beta catenin. PDLIM2 function is associated with tumour suppression and also with the
Autor:
Elham Jaberi, Lluís Riera-Ponsati, Wei Qi Guinevere Sew, Shohreh Issazadeh-Navikas, Karsten Ruscher, Emilie Tresse
Publikováno v:
EMBO J
Mitochondrial homeostasis is essential for providing cellular energy, particularly in resource‐demanding neurons, defects in which cause neurodegeneration, but the function of interferons (IFNs) in regulating neuronal mitochondrial homeostasis is u
Autor:
Emilie Tresse
Publikováno v:
Proceedings of the European Microscopy Congress 2020.
Autor:
Alexia Montalant, Thomas Gasser, Marco Prinz, Patrick Ejlerskov, Joana Magalhaes, Erling Hu, Shohreh Issazadeh-Navikas, Emilie Tresse, Susana Aznar, Ali Sharifi-Zarchi, Yawei Liu, Carsten Friis Rundsten, Tomasz Brudek, Jesper B. Andersen, Eva Maria Meier Carlsen, Manu Sharma, Jean-François Perrier, Rasmus Rydbirk, Letizia Satriano, Konstantin Khodosevich, Andrea Marin
Publikováno v:
Magalhaes, J, Tresse, E, Ejlerskov, P, Hu, E, Liu, Y, Marin, A, Montalant, A, Satriano, L, Rundsten, C F, Carlsen, E M M, Rydbirk, R, Sharifi-Zarchi, A, Andersen, J B, Aznar, S, Brudek, T, Khodosevich, K, Prinz, M, Perrier, J F M, Sharma, M, Gasser, T & Issazadeh-Navikas, S 2021, ' PIAS2-mediated blockade of IFN-β signaling : a basis for sporadic Parkinson disease dementia ', Molecular Psychiatry, vol. 26, pp. 6083–6099 . https://doi.org/10.1038/s41380-021-01207-w
Molecular Psychiatry
Molecular Psychiatry
Familial Parkinson disease (PD) is associated with rare genetic mutations, but the etiology in most patients with sporadic (s)PD is largely unknown, and the basis for its progression to dementia (sPDD) is poorly characterized. We have identified that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29a8e8c7d012f8dd270676bd23231b7
https://curis.ku.dk/portal/da/publications/pias2mediated-blockade-of-ifn-signaling(d386990f-e2ac-44da-a127-61b65c96e865).html
https://curis.ku.dk/portal/da/publications/pias2mediated-blockade-of-ifn-signaling(d386990f-e2ac-44da-a127-61b65c96e865).html
Autor:
Emilie Tresse, Joachim Weischenfeldt, Kirsten Grønbæk, Shohreh Issazadeh-Navikas, Elham Jaberi
Publikováno v:
Jaberi, E, Tresse, E, Grønbæk, K, Weischenfeldt, J & Issazadeh-Navikas, S 2020, ' Identification of unique and shared mitochondrial DNA mutations in neurodegeneration and cancer by single-cell mitochondrial DNA structural variation sequencing (MitoSV-seq) ', EBioMedicine, vol. 57, 102868, pp. 1-17 . https://doi.org/10.1016/j.ebiom.2020.102868
EBioMedicine, Vol 57, Iss, Pp 102868-(2020)
EBioMedicine
EBioMedicine, Vol 57, Iss, Pp 102868-(2020)
EBioMedicine
Background: Point mutations and structural variations (SVs) in mitochondrial DNA (mtDNA) contribute to many neurodegenerative diseases. Technical limitations and heteroplasmy, however, have impeded their identification, preventing these changes from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dcdfb3950b32ff6118ffa396c794707
https://curis.ku.dk/ws/files/246674452/1_s2.0_S2352396420302437_main.pdf
https://curis.ku.dk/ws/files/246674452/1_s2.0_S2352396420302437_main.pdf
Autor:
Tso-Pang Yao, Florian A. Salomons, Laura C. Bott, J. Paul Taylor, Jouni Vesa, Nico P. Dantuma, Virginia Kimonis, Emilie Tresse
Publikováno v:
Karolinska Institutet
VCP (VCP/p97) is a ubiquitously expressed member of the AAA+-ATPase family of chaperone-like proteins that regulates numerous cellular processes including chromatin decondensation, homotypic membrane fusion, and ubiquitin-dependent protein degradatio
Autor:
Rosemary O'Connor, Orla T. Cox, Ravi Kiran-Deevi, Milan Bustamante-Garrido, Sandra O'Shea, Emilie Tresse
Publikováno v:
Frontiers in Endocrinology, Vol 6 (2015)
Frontiers in Endocrinology
Frontiers in Endocrinology
IGF-1R expression and activation levels generally cannot be correlated in cancer cells, suggesting that cellular proteins may modulate IGF-1R activity. Strong candidates for such modulation are found in cell-matrix and cell–cell adhesion signaling