Methylobacterium genome sequences: a reference blueprint to investigate microbial metabolism of C1 compounds from natural and industrial sources.

Autor: Stéphane Vuilleumier, Ludmila Chistoserdova, Ming-Chun Lee, Françoise Bringel, Aurélie Lajus, Yang Zhou, Benjamin Gourion, Valérie Barbe, Jean Chang, Stéphane Cruveiller, Carole Dossat, Will Gillett, Christelle Gruffaz, Eric Haugen, Edith Hourcade, Ruth Levy, Sophie Mangenot, Emilie Muller, Thierry Nadalig, Marco Pagni, Christian Penny, Rémi Peyraud, David G Robinson, David Roche, Zoé Rouy, Channakhone Saenampechek, Grégory Salvignol, David Vallenet, Zaining Wu, Christopher J Marx, Julia A Vorholt, Maynard V Olson, Rajinder Kaul, Jean Weissenbach, Claudine Médigue, Mary E Lidstrom

Publikováno v: PLoS ONE, Vol 4, Iss 5, p e5584 (2009)

BACKGROUND:Methylotrophy describes the ability of organisms to grow on reduced organic compounds without carbon-carbon bonds. The genomes of two pink-pigmented facultative methylotrophic bacteria of the Alpha-proteobacterial genus Methylobacterium, t

Externí odkaz: https://doaj.org/article/1e4c233bb7ef4eb38952c4ab4c0b34f3

Colonic overexpression of the T-type calcium channel Cav3.2 in a mouse model of visceral hypersensitivity and in irritable bowel syndrome patients

Autor: Ludivine Boudieu, Michel Dapoigny, Marion Goutte, Emilie Muller, Denis Ardid, Christophe Mallet, Elodie Picard, Bruno Pereira, Frederic A. Carvalho, Youssef Aissouni, Agathe Gelot, Julien Scanzi, Juliette Joubert-Zakeyh, A. Accarie

Publikováno v: Neurogastroenterology & Motility. 28:1632-1640

Background Among the different mechanisms involved in irritable bowel syndrome (IBS) physiopathology, visceral hypersensitivity seems to play a key role. It involves sensitization of the colonic primary afferent fibers, especially through an overexpr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::97f57c8f4e1c8eab25849cf9ebfa5dd1
https://doi.org/10.1111/nmo.12860

Comparative effects of alpha 2 delta-1 ligands in mouse models of colonic hypersensitivity

Autor: Celine Silberberg, Ludivine Boudieu, Alain Eschalier, Mathieu Meleine, Emilie Muller, Vassilia Theodorou, Julien Matricon, Amandine Lashermes, Frederic A. Carvalho, Denis Ardid, Agathe Gelot

Publikováno v: World Journal of Gastroenterology
World Journal of Gastroenterology, 2016, 22 (31), pp.7111-7123. ⟨10.3748/wjg.v22.i31.7111⟩
World Journal of Gastroenterology, Baishideng Publishing Group Co. Limited, 2016, 22 (31), pp.7111-7123. ⟨10.3748/wjg.v22.i31.7111⟩
World Journal of Gastroenterology 31 (22), 7111-7123. (2016)

International audience; AIM: To investigate anti-hypersensitive effects of alpha 2 delta-1 ligands in non-inflammatory and inflammation-associated colonic hypersensitivity (CHS) mouse models. METHODS: To induce an inflammation-associated CHS, 1% dext

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d5716078f624e565bfd57db0db964c
https://hal.inrae.fr/hal-02636301

T-type calcium channels contribute to colonic hypersensitivity in a rat model of irritable bowel syndrome

Autor: Juan F. Sanguesa Ferrer, Emilie Muller, Fabrice Marger, Abdelkrim Alloui, Terrance P. Snutch, Joël Nargeot, Emmanuel Bourinet, Julien Matricon, Denis Ardid, Christian Barrère, Anne Pizzoccaro, Alain Eschalier, Agathe Gelot

Publikováno v: Proceedings of the National Academy of Sciences. 108:11268-11273

The symptoms of irritable bowel syndrome (IBS) include significant abdominal pain and bloating. Current treatments are empirical and often poorly efficacious, and there is a need for the development of new and efficient analgesics aimed at IBS patien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d0e9b654c3923485d0f0686f5e841a
https://doi.org/10.1073/pnas.1100869108

Despite GABAergic neurotransmission, GABAergic innervation does not compensate for the defect in glycine receptor postsynaptic aggregation in spastic mice

Autor: Antoine Triller, Anne-Laure Scain, Pascal Legendre, Hervé Le Corronc, Emilie Muller

Publikováno v: European Journal of Neuroscience
European Journal of Neuroscience, Wiley, 2008, 27 (10), pp.2529-41. ⟨10.1111/j.1460-9568.2008.06217.x⟩
European Journal of Neuroscience, 2008, 27 (10), pp.2529-41. ⟨10.1111/j.1460-9568.2008.06217.x⟩

International audience; In the hypoglossal nucleus of wild-type mice, early mixed glycinergic-GABAergic inhibitory transmission becomes mainly glycinergic during postnatal maturation. In spastic mice (SPA), a model of human hyperekplexic syndrome, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ad026daa4760884631f386eec3d1df2
https://doi.org/10.1111/j.1460-9568.2008.06217.x