Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Emilie K Grasset"'
Autor:
Leire de Campos‐Mata, Sonia Tejedor Vaquero, Roser Tachó‐Piñot, Janet Piñero, Emilie K Grasset, Itziar Arrieta Aldea, Natalia Rodrigo Melero, Carlo Carolis, Juan P Horcajada, Andrea Cerutti, Judit Villar‐García, Giuliana Magri
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 9, Pp n/a-n/a (2021)
Abstract Objectives SARS‐CoV‐2 infection induces virus‐reactive memory B cells expressing unmutated antibodies, which hints at their emergence from naïve B cells. Yet, the dynamics of virus‐specific naïve B cells and their impact on immunit
Externí odkaz:
https://doaj.org/article/28a562c0f76843f5b9ea468ad9d87eab
Autor:
Arun Cumpelik, Evan Cody, Samuel Mon-Wei Yu, Emilie K. Grasset, David Dominguez-Sola, Andrea Cerutti, Peter S. Heeger
Publikováno v:
The Journal of Immunology. 210:19-23
T cell–independent (TI) B cell responses to nonprotein Ags involve multiple cues from the innate immune system. Neutrophils express complement receptors and activated neutrophils can release BAFF, but mechanisms effectively linking neutrophil activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce17524efd06377f4662ca50b6058992
https://doi.org/10.4049/jimmunol.2200410
https://doi.org/10.4049/jimmunol.2200410
Autor:
Jordi Sintes, Maurizio Gentile, Shuling Zhang, Yolanda Garcia-Carmona, Giuliana Magri, Linda Cassis, Daniel Segura-Garzón, Alessandra Ciociola, Emilie K. Grasset, Sabrina Bascones, Laura Comerma, Marc Pybus, David Lligé, Irene Puga, Cindy Gutzeit, Bing He, Wendy DuBois, Marta Crespo, Julio Pascual, Anna Mensa, Juan Ignacio Aróstegui, Manel Juan, Jordi Yagüe, Sergi Serrano, Josep Lloreta, Eric Meffre, Michael Hahne, Charlotte Cunningham-Rundles, Beverly A. Mock, Andrea Cerutti
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Marginal zone B cells differentiate into plasma cells rapidly in response to T-cell-independent antigens, but how they do so is not clear. Here the authors show TACI cooperates with TLR signalling to drive mTOR activity and subsequent class switching
Externí odkaz:
https://doaj.org/article/55fa5c77ea474673980a024897c7214c
Autor:
Mathieu Uzzan, Jerome C. Martin, Luka Mesin, Alexandra E. Livanos, Tomas Castro-Dopico, Ruiqi Huang, Francesca Petralia, Giuliana Magri, Shashi Kumar, Qing Zhao, Adam K. Rosenstein, Minami Tokuyama, Keshav Sharma, Ryan Ungaro, Roman Kosoy, Divya Jha, Jeremy Fischer, Harpriya Singh, Mary E. Keir, Nandhini Ramamoorthi, William E. O’Gorman, Benjamin L. Cohen, Adeeb Rahman, Francesca Cossarini, Akihiro Seki, Louise Leyre, Sonia Tejedor Vaquero, Sakteesh Gurunathan, Emilie K. Grasset, Bojan Losic, Marla Dubinsky, Alexander J. Greenstein, Zoe Gottlieb, Peter Legnani, James George, Haritz Irizar, Aleksandar Stojmirovic, Carrie Brodmerkel, Andrew Kasarkis, Bruce E. Sands, Glaucia Furtado, Sergio A. Lira, Zewen K. Tuong, Huaibin M. Ko, Andrea Cerutti, Charles O. Elson, Menna R. Clatworthy, Miriam Merad, Mayte Suárez-Fariñas, Carmen Argmann, Jason A. Hackney, Gabriel D. Victora, Gwendalyn J. Randolph, Ephraim Kenigsberg, Jean Frederic Colombel, Saurabh Mehandru
Publikováno v:
Nat Med
B cells, which are critical for intestinal homeostasis, remain understudied in ulcerative colitis (UC). In this study, we recruited three cohorts of patients with UC (primary cohort, n = 145; validation cohort 1, n = 664; and validation cohort 2, n =
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::174661bdc81a07d2cf2f022bc6ddd914
https://doi.org/10.1038/s41591-022-01680-y
https://doi.org/10.1038/s41591-022-01680-y
Autor:
Emilie K. Grasset, Theresa Alenghat
Publikováno v:
Immunity. 55(12)
Cellular dynamics that influence mucosal healing are not well understood. In this issue of Immunity, Frede, Czarnewski, Monasterio et al. find that B cells accumulate in the colon following intestinal injury. These B cells impair epithelial repair by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c3b9a6ab717b6f49c44a020817edf8
https://pubmed.ncbi.nlm.nih.gov/36516815
https://pubmed.ncbi.nlm.nih.gov/36516815
Autor:
Giuliana Magri, Carlo Carolis, Sonia Tejedor Vaquero, Roser Tachó-Piñot, Emilie K. Grasset, Janet Piñero, Judit Villar-García, Juan Pablo Horcajada, Itziar Arrieta Aldea, Natalia Rodrigo Melero, Leire de Campos-Mata, Andrea Cerutti
Publikováno v:
de Campos Mata, L, Tejedor Vaquero, S & Tachó Piñot, R 2021, ' SARS-CoV-2 sculpts the immune system to induce sustained virus-specific naïve-like and memory B-cell responses ', Clinical & translational immunology, vol. 10, no. 9, e1339 . https://doi.org/10.1002/cti2.1339
Clinical & Translational Immunology
Clinical & Translational Immunology, Vol 10, Iss 9, Pp n/a-n/a (2021)
Clinical & Translational Immunology
Clinical & Translational Immunology, Vol 10, Iss 9, Pp n/a-n/a (2021)
Objectives SARS‐CoV‐2 infection induces virus‐reactive memory B cells expressing unmutated antibodies, which hints at their emergence from naïve B cells. Yet, the dynamics of virus‐specific naïve B cells and their impact on immunity and imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f3291835ed88f31644200a18a0d3cf7
https://doi.org/10.1002/cti2.1339
https://doi.org/10.1002/cti2.1339
Autor:
Yuan-Shuo Wang, Reza Mehrazin, Adam M. Farkas, Amir Horowitz, Jorge Daza, Rachel Brody, Matthew D. Galsky, Nina Bhardwaj, John P. Sfakianos, Li Wang, Emilie K. Grasset, Giuliana Magri, Robert Sebra, Jun Zhu, Kristin G. Beaumont, Peter Wiklund
Publikováno v:
Journal of Urology. 206
INTRODUCTION AND OBJECTIVE:Tumor infiltrating B cells in bladder cancer (BCa) have been associated with cancer invasion, but little is understood regarding their role in the tumor microenvironment....
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a7244d7eb76ba5587410682f5e6f80e
https://doi.org/10.1097/ju.0000000000002106.19
https://doi.org/10.1097/ju.0000000000002106.19
Autor:
Yuan-Shuo Wang, John P. Sfakianos, Li Wang, Peter Wiklund, Andrew Charap, Amir Horowitz, Ketan K. Badani, Giuliana Magri, Rafael Cabal, Yong Lee, Jorge Daza, Rachel Brody, Bérengère Salomé, Nina Bharwadj, Emilie K. Grasset, Kristin G. Beaumont, Jun Zhu, Robert Sebra, Reza Mehrazin, Adam M. Farkas, Dominic LaRoche, Matthew D. Galsky
Publikováno v:
Journal of Urology. 206
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b75aac299506c1ece7cdb2b4def6ec78
https://doi.org/10.1097/ju.0000000000002056.03
https://doi.org/10.1097/ju.0000000000002056.03
Autor:
García Prat M, Charlotte Cunningham-Rundles, Emilie K. Grasset, Giuliana Magri, Cindy Gutzeit, Paul J. Maglione, Pybus M, Martín Nalda A, Dieli-Crimi R, Lewis Tomalin, Tejedor Vaquero S, Tachó-Piñot R, Graham J. Britton, Martinez Gallo M, Suarez-Farina M, Andrea Cerutti, Saurabh Mehandru, Jose C. Clemente, Veeramreddy Pk, Jeremiah J. Faith, Dean B. Matthews
SUMMARYThe gut microbiota enhances systemic immunoglobulin G (IgG) responses to vaccines. However, it is unknown whether this effect involves IgA, a mucosal antibody that coats intestinal microbes. Here we found that gut IgA increased peripheral IgG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ecceb1a4f775757ba1523fa3a1c1703
https://doi.org/10.1101/2021.04.29.439534
https://doi.org/10.1101/2021.04.29.439534
Autor:
Andrea Cerutti, Emilie K. Grasset
Publikováno v:
Journal of Experimental Medicine. 217
In this issue, Kabbert et al. (https://doi.org/10.1084/jem.20200275) show that intestinal antibodies from healthy subjects or patients with Crohn’s disease cross-target diverse but distinct communities of the gut microbiota through a mechanism invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f6e8a7b398c57818343144a3ccef24
https://doi.org/10.1084/jem.20201340
https://doi.org/10.1084/jem.20201340