Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Emilie Indersie"'
Autor:
Anthony Brown, Qingfei Pan, Li Fan, Emilie Indersie, Cheng Tian, Nikolai Timchenko, Liyuan Li, Baranda S. Hansen, Haiyan Tan, Meifen Lu, Junmin Peng, Shondra M. Pruett-Miller, Jiyang Yu, Stefano Cairo, Liqin Zhu
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
In hepatoblastoma, the RRM2 subunit of ribonucleotide reductase is associated with disease progression, but in response to chemotherapy, subunit switching favours the less active RRM2B subunit which supports hepatoblastoma cell survival and relapse.
Externí odkaz:
https://doaj.org/article/ae5989f069384abbaef73e2aa057eb83
Autor:
Ashby Kissoondoyal, Emily DeSousa, Paula R. Quaglietta, Emilie Indersie, Stefano Cairo, David Malkin, Lisandro Luques, Reto M. Baertschiger
Publikováno v:
Cancer Research. 83:3540-3540
Background: Hepatoblastoma (HB) is the most frequent liver tumor in children. While most tumors respond well to treatment with good outcomes, there are a subgroup of refractory tumors for which novel therapies are required. Emerging literature has su
Autor:
Lisandro Luques, Ashby Kissoondoyal, Emily De Sousa, Paula Quaglietta, David Malkin, Stefano Cairo, Emilie Indersie, Reto Baertschiger
Publikováno v:
Cancer Research. 83:3539-3539
Hepatoblastoma (HB) is the most common pediatric primary liver malignancy and represents about 1% of all pediatric tumors. Incidence of HB has been increasing in the past 10 years. Risk stratification of HB patients is established by the extent of th
Autor:
Aniello Federico, Apurva Gopisetty, Didier Surdez, Yasmine Iddir, Alexandra Saint-Charles, Justyna Wierzbinska, Andreas Schlicker, Richard Volckmann, Danny Zwijnenburg, Sara Colombetti, Olaf Heidenreich, Fatima Iradier, Heinrich Kovar, Jan-Henning Klusmann, Klaus-Michael Debatin, Simon Bomken, Christina Guttke, Maureen M. Hattersley, Frédéric Colland, Ashley Strougo, María José Guillén, Louis Chesler, Chris Jones, Maria Eugénia Marques da Costa, Katia Scotlandi, Massimo Moro, Beat Schäfer, Marco Wachtel, Johannes Gojo, Walter Berger, Ángel Montero Carcaboso, Dennis Gürgen, Jens Hoffmann, Emilie Indersie, Stefano Cairo, Julia Schueler, Nicole Huebener, Johannes H. Schulte, Jan J. Molenaar, Birgit Geoerger, David J. Shields, Hubert N. Caron, Gilles Vassal, Lou F. Stancato, Stefan M. Pfister, Natalie Jäger, Jan Koster, Marcel Kool, Gudrun Schleiermacher
Publikováno v:
Cancer Research. 83:3571-3571
Cancer represents a leading cause of death by disease in childhood. Pediatric tumors exhibit a high intertumoral heterogeneity, as different tumor types and subtypes have emerged with peculiar molecular and clinical features; however, compared to can
Autor:
Anaïs Chivet, Pascale Varlet, Albane Gareton, Stéphanie Puget, Arnault Tauziède-Espariat, Sophie Huybrechts, Emilie Indersie, Fabrice Chrétien, Olivier Ayrault, Mélanie Pagès, Alexandre Roux, Emmanuèle Lechapt, Christelle Dufour
Publikováno v:
American Journal of Surgical Pathology. 45:558-566
Medulloblastomas (MBs) are the most frequent childhood malignant brain tumor. Four histopathologic variants and 4 genetic subgroups have been defined in the World Health Organization (WHO) 2016 Classification and constitute major risk stratification
Autor:
Anthony Ray Brown, Emilie Indersie, Shaina Porter, Baranda Hansen, Li Fan, Liyuan Li, Cheng Tian, Haiyan Tan, Shondra Miller, Junmin Peng, Stefano Cairo, Liqin Zhu
Publikováno v:
Cancer Research. 82:3963-3963
Background and Rationale: Hepatoblastoma is the most common primary liver cancer in infants and young children. Despite being a very rare cancer that accounts for only 0.5-2% if all childhood cancer cases, HB has the largest increase in incidence amo
Autor:
Agnieszka Pietrzyk, Emilie Indersie, Olivier Deas, Jean-Gabriel Judde, Marcin Krzykawski, Stefano Cairo
Publikováno v:
Cancer Research. 82:176-176
One of the biggest challenges in preclinical oncology is the lack of models faithfully recapitulating the physiological and pathophysiological features of the native tumor. PDXs (Patient-Derived Xenografts), developed in immune-compromised mice, have
Autor:
Sophie Huybrechts, Caroline Rossoni, Christelle Dufour, Dominique Valteau-Couanet, Gwénaël Le Teuff, Stéphanie Puget, Rachid Abbas, Olivier Ayrault, Léa Guerrini-Rousseau, Arnault Tauziède-Espariat, Jacques Grill, Emilie Indersie, Pascale Varlet, Anaïs Chivet
Publikováno v:
Cancers
Volume 13
Issue 1
Cancers, MDPI, 2020, 13 (1), pp.53. ⟨10.3390/cancers13010053⟩
Cancers, 2020, 13 (1), pp.53. ⟨10.3390/cancers13010053⟩
Cancers, Vol 13, Iss 53, p 53 (2021)
Volume 13
Issue 1
Cancers, MDPI, 2020, 13 (1), pp.53. ⟨10.3390/cancers13010053⟩
Cancers, 2020, 13 (1), pp.53. ⟨10.3390/cancers13010053⟩
Cancers, Vol 13, Iss 53, p 53 (2021)
Given the very poor prognosis for children with recurrent medulloblastoma, we aimed to identify prognostic factors for survival post-relapse in children with childhood medulloblastoma. We retrospectively collected clinico-biological data at diagnosis
Autor:
Michael Rusch, Aksana Vasilyeva, Marc Remke, Paul A. Northcott, Tanvi Sharma, Finn Wesenberg, Andrey Korshunov, Peter Lichter, Kristian W. Pajtler, Natalie Jäger, Sonia Partap, Till Milde, John R. Crawford, Amar Gajjar, Stefan Rutkowski, Nicholas G. Gottardo, Kyle S. Smith, Daniel C. Bowers, Christoffer Johansen, Sebastian M. Waszak, Tobias Rausch, Christelle Dufour, Damarys Loew, David T.W. Jones, Geoffrey Neale, Olaf Witt, Tone Eggen, Ivo Buchhalter, Olivier Ayrault, Dominik Sturm, Maria Feychting, Jesus Garcia-Lopez, Michael A. Grotzer, Claudia E. Kuehni, Emilie Indersie, Brandon J. Wainwright, Stéphanie Puget, Joy Nakitandwe, Marcel Kool, David W. Ellison, Marina Ryzhova, Jules Kerssemakers, Birgitta Lannering, Amy A Smith, Brent A. Orr, Joachim Schüz, Tina Veje Andersen, Murali Chintagumpala, Brian Gudenas, Bérangère Lombard, Antoine Forget, Laurence Brugières, Marija Kojic, Kim E. Nichols, Jennifer Hadley, Martin Röösli, Kristina Kjærheim, Anne Bendel, Stefan M. Pfister, Kayla V. Hamilton, Ruth G. Tatevossian, Giles W. Robinson, Jan O. Korbel
Publikováno v:
Nature
Nature, Nature Publishing Group, 2020, 580, pp.396-401. ⟨10.1038/s41586-020-2164-5⟩
Nature, Nature Publishing Group, 2020, 580, pp.396-401. ⟨10.1038/s41586-020-2164-5⟩
Cancer genomics has illuminated a wide spectrum of genes and core molecular processes contributing to human malignancy. Still, the genetic and molecular basis of many cancers remains only partially explained. Genetic predisposition accounts for 5-10%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a6e2d9961a298612513b23146265b6
https://europepmc.org/articles/PMC7430762/
https://europepmc.org/articles/PMC7430762/
Autor:
Michael A. Grotzer, Marina Ryzhova, Kyle S. Smith, Olaf Witt, Ivo Buchhalter, Dominic Sturm, Paul A. Northcott, David T.W. Jones, Kayla V. Hamilton, Sonia Partap, Emilie Indersie, Daniel C. Bowers, Ruth G. Tatevossian, Anne Bendel, Laurence Brugières, Till Milde, Christelle Dufour, Stefan M. Pfister, Tobias Rausch, M Remke, Jan O. Korbel, Amy M. Smith, Tanvi Sharma, Sebastian M. Waszak, Giles W. Robinson, Stefan Rutkowski, Brent A. Orr, Natalie Jäger, Andrey Korshunov, Stéphanie Puget, Olivier Ayrault, Brandon J. Wainwright, Marcel Kool, Antoine Forget, Jennifer Hadley, Marija Kojic, Kim E. Nichols, Amar Gajjar, Damarys Loew, Peter Lichter, Garcia-Lopez Jesus, Kristian W. Pajtler, John R. Crawford, Nicholas G. Gottardo, David W. Ellison, Bérangère Lombard, Brian Gudenas, Murali Chintagumpala
Publikováno v:
Neuro-Oncology
BACKGROUND Our previous analysis of established cancer predisposition genes in medulloblastoma (MB) identified pathogenic germline variants in ~5% of all patients. Here, we extended our analysis to include all protein-coding genes. METHODS Case-contr