Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Emilie Henin"'
Autor:
Charlotte Cuerq, Emilie Henin, Lioara Restier, Emilie Blond, Jocelyne Drai, Christophe Marçais, Mathilde Di Filippo, Christian Laveille, Marie-Caroline Michalski, Pierre Poinsot, Cyrielle Caussy, Agnès Sassolas, Philippe Moulin, Emmanuelle Reboul, Sybil Charriere, Emile Levy, Alain Lachaux, Noël Peretti
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 9, Pp 1640-1648 (2018)
Abetalipoproteinemia (ABL) and chylomicron retention disease (CMRD) are extremely rare recessive forms of hypobetalipoproteinemia characterized by intestinal lipid malabsorption and severe vitamin E deficiency. Vitamin E is often supplemented in the
Externí odkaz:
https://doaj.org/article/d3ae3482ce1842fd8028966debda54e5
Autor:
Laurence Kraus-Berthier, Marylore Chenel, Philippe B. Pierrillas, Magali Amiel, François Bouzom, Michel Tod, Julien Ogier, Emilie Henin
Publikováno v:
Investigational New Drugs. 38:1796-1806
The attrition rate of anticancer drugs during the clinical development remains very high. Interspecies extrapolation of anticancer drug pharmacodynamics (PD) could help to bridge the gap between preclinical and clinical settings and to improve drug d
Publikováno v:
Advances in therapy. 38(10)
Tacrolimus, the cornerstone of transplantation immunosuppression, is a narrow therapeutic index drug with a low and highly variable bioavailability. Therapeutic drug monitoring based on trough level assessment is mandatory in order to target a person
Autor:
Philippe B. Pierrillas, Marylore Chenel, Michel Tod, Emilie Henin, Laurence Kraus-Berthier, François Bouzom, Julien Ogier
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 367:414-424
The Bcl-2 inhibitor S 55746 ((S)-N-(4-hydroxyphenyl)-3-(6-(3-(morpholinomethyl)-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)benzo[d][1,3]dioxol-5-yl)-N-phenyl-5,6,7,8-tetrahydroindolizine-1-carboxamide) is able to restore apoptosis functions impaired b
Autor:
Philippe Moulin, Jocelyne Drai, Emmanuelle Reboul, Emile Levy, Charlotte Cuerq, Lioara Restier, Noël Peretti, Mathilde Di Filippo, Marie-Caroline Michalski, Alain Lachaux, Emilie Blond, Pierre Poinsot, Agnès Sassolas, Sybil Charrière, Cyrielle Caussy, Christian Laveille, Christophe Marçais, Emilie Henin
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2018, 59 (9), pp.1640--1648
Journal of Lipid Research, 2018, 59 (9), pp.1640-1648. ⟨10.1194/jlr.M085043⟩
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2018, 59 (9), pp.1640-1648. ⟨10.1194/jlr.M085043⟩
Journal of Lipid Research, Vol 59, Iss 9, Pp 1640-1648 (2018)
Journal of Lipid Research, 2018, 59 (9), pp.1640--1648
Journal of Lipid Research 9 (59), 1640-1648. (2018)
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2018, 59 (9), pp.1640--1648
Journal of Lipid Research, 2018, 59 (9), pp.1640-1648. ⟨10.1194/jlr.M085043⟩
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2018, 59 (9), pp.1640-1648. ⟨10.1194/jlr.M085043⟩
Journal of Lipid Research, Vol 59, Iss 9, Pp 1640-1648 (2018)
Journal of Lipid Research, 2018, 59 (9), pp.1640--1648
Journal of Lipid Research 9 (59), 1640-1648. (2018)
International audience; Abetalipoproteinemia (ABL) and chylomicron retention disease (CMRD) are extremely rare recessive forms of hypobetalipoproteinemia characterized by intestinal lipid malabsorption and severe vitamin E deficiency. Vitamin E is of
Autor:
Estelle Bourbon, Emilie Henin, Aurore Gouraud, Florence Ranchon, Clémentine Sarkozy, Amandine Baudouin, Nicolas Vantard, Fadhela Bouafia-Sauvy, Gilles Salles, Thierry Vial, Emmanuel Bachy, Lionel Karlin, Catherine Rioufol, Anne Gaelle Caffin, Vérane Schwiertz
Publikováno v:
Hematological Oncology. 36:399-406
The aim of this retrospective cohort study was to investigate the incidence of delayed methotrexate elimination in patients treated with high-dose methotrexate (≥1 g/m2 ) for haematological malignancy and to identify the impact of interacting drugs
Publikováno v:
Biopharmaceutics & Drug Disposition. 38:351-362
Purpose The chromone derivative MBL-II-141, specifically designed to inhibit ABCG2, was previously demonstrated to combine strong inhibition potency, low toxicity and good efficiency in reversing resistance to irinotecan in a xenografted mouse model.
Autor:
Benoit You, Gilles Freyer, Athanassios Iliadis, Christophe Meille, Jérôme Guitton, Dominique Barbolosi, Emilie Henin
Publikováno v:
Breast Cancer Research and Treatment. 156:331-341
The MODEL1 trial is the first model-driven phase I/II dose-escalation study of densified docetaxel plus epirubicin administration in metastatic breast cancer patients, a regimen previously known to induce unacceptable life-threatening toxicities. The
Publikováno v:
Int J Gynecol Cancer
ObjectivesIn low-risk gestational trophoblastic neoplasia, chemotherapy effect is monitored and adjusted with serum human chorionic gonadotrophin (hCG) levels. Mathematical modeling of hCG kinetics may allow prediction of methotrexate (MTX) resistanc
Autor:
Marc Cerou, Emilie Henin, Chao Chen, Alienor Berges, Claire Ambery, Tarjinder Sahota, Lia Liefaard, Stefano Zamuner
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 165(1)
A time-to-event (TTE) model has been developed to characterize a histopathology toxicity that can only be detected at the time of animal sacrifice. The model of choice was a hazard model with a Weibull distribution and dose was a significant covariat