Zobrazeno 1 - 10 of 35 pro vyhledávání: '"Emilie Fleur Gautier"'
1
Akademický článek
Red blood cell proteomics reveal remnant protein biosynthesis and folding pathways in PIEZO1-related hereditary xerocytosis
Autor: Alexis Caulier, Nicolas Jankovsky, Emilie Fleur Gautier, Wassim El Nemer, Corinne Guitton, Hakim Ouled-Haddou, François Guillonneau, Patrick Mayeux, Virginie Salnot, Johanna Bruce, Véronique Picard, Loïc Garçon
Publikováno v: Frontiers in Physiology, Vol 13 (2022)
Hereditary xerocytosis is a dominant red cell membrane disorder characterized by an increased leak of potassium from the inside to outside the red blood cell membrane, associated with loss of water leading to red cell dehydration and chronic hemolysi
Externí odkaz: https://doaj.org/article/41d3e8f282a840d9adfbdf38314def55
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2
Akademický článek
XPO1 regulates erythroid differentiation and is a new target for the treatment of β-thalassemia
Autor: Flavia Guillem, Michaël Dussiot, Elia Colin, Thunwarat Suriyun, Jean Benoit Arlet, Nicolas Goudin, Guillaume Marcion, Renaud Seigneuric, Sebastien Causse, Patrick Gonin, Marc Gastou, Marc Deloger, Julien Rossignol, Mathilde Lamarque, Zakia Belaid Choucair, Emilie Fleur Gautier, Sarah Ducamp, Julie Vandekerckhove, Ivan C. Moura, Thiago Trovati Maciel, Carmen Garrido, Xiuli An, Patrick Mayeux, Narla Mohandas, Geneviève Courtois, Olivier Hermine
Publikováno v: Haematologica, Vol 105, Iss 9 (2019)
β-thalassemia major (β-TM) is an inherited hemoglobinopathy caused by a quantitative defect in the synthesis of β-globin chains of hemoglobin, leading to the accumulation of free a-globin chains that aggregate and cause ineffective erythropoiesis.
Externí odkaz: https://doaj.org/article/9c8681ff1975469eabfa5bbd4e3b3606
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4
Akademický článek
Comprehensive Proteomic Analysis of Human Erythropoiesis
Autor: Emilie-Fleur Gautier, Sarah Ducamp, Marjorie Leduc, Virginie Salnot, François Guillonneau, Michael Dussiot, John Hale, Marie-Catherine Giarratana, Anna Raimbault, Luc Douay, Catherine Lacombe, Narla Mohandas, Frédérique Verdier, Yael Zermati, Patrick Mayeux
Publikováno v: Cell Reports, Vol 16, Iss 5, Pp 1470-1484 (2016)
Mass spectrometry-based proteomics now enables the absolute quantification of thousands of proteins in individual cell types. We used this technology to analyze the dynamic proteome changes occurring during human erythropoiesis. We quantified the abs
Externí odkaz: https://doaj.org/article/f796025f11234209aeda0500f5e4e97a
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5
p53 activation during ribosome biogenesis regulates normal erythroid differentiation
Autor: François Morlé, Stéphane Giraudier, Eric Soler, Naomi Taylor, Charlotte Andrieu-Soler, Olivier Hermine, Patrick Mayeux, Célia Floquet, Rose Ann Padua, Frédérique Verdier, Sarah Ducamp, Michaela Fontenay, Mohammad Salma, Elisabeth M. Cramer-Borde, Ismael Boussaid, Anna Raimbault, Isabelle Hatin, Diane d'Allard, Amandine Houvert, Narla Mohandas, Boris Guyot, Emilie-Fleur Gautier, Sandrina Kinet, Marjorie Leduc, Pierre-Emmanuel Gleizes, Jean-Jacques Diaz, Salomé Le Goff, François Guillonneau, Nathalie Montel-Lehry
Publikováno v: Blood
Blood, American Society of Hematology, 2021, 137 (1), pp.89-102. ⟨10.1182/blood.2019003439⟩
Blood, 2020, ⟨10.1182/blood.2019003439⟩
Blood, American Society of Hematology, 2020, ⟨10.1182/blood.2019003439⟩
Blood, American Society of Hematology, 2020, 137 (1), pp.89-102. ⟨10.1182/blood.2019003439⟩
Blood, 2021, 137 (1), pp.89-102. ⟨10.1182/blood.2019003439⟩
The role of ribosome biogenesis in erythroid development is supported by the recognition of erythroid defects in ribosomopathies in both Diamond-Blackfan anemia and 5q− syndrome. Whether ribosome biogenesis exerts a regulatory function on normal er
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6c14ec0b5187882ecdef968124a4606
https://doi.org/10.1182/blood.2019003439
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7
Multiparametric characterization of red blood cell physiology after hypotonic dialysis based drug encapsulation process
Autor: Angelo D'Alessandro, Travis Nemkov, Virginie Salnot, Alexander Scheer, Philippe Connes, Philippe Joly, Florian Dupuy, Bastien Laperrousaz, Catherine Lavazec, Emilie-Fleur Gautier, Elie Nader, Diana Piedrahita, Agnès Cibiel, Patrick Mayeux, Mélanie Robert
Publikováno v: Acta Pharmaceutica Sinica B
Acta Pharmaceutica Sinica B, 2022, 12 (4), pp.2089-2102. ⟨10.1016/j.apsb.2021.10.018⟩
International audience; Red blood cells (RBCs) can act as carriers for therapeutic agents and can substantially improve the safety, pharmacokinetics, and pharmacodynamics of many drugs. Maintaining RBCs integrity and lifespan is important for the eff
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c291c0a30ebf0b95dcc0d8a71b3309d3
https://hal.science/hal-03807801
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8
Integrated analyses of translatome and proteome identify the rules of translation selectivity in RPS14-deficient cells
Autor: Michaela Fontenay, Pierre-Julien Viailly, Bertrand Cosson, Patrick Mayeux, Anna Raimbault, Dina Al Dulaimi, Emilie-Fleur Gautier, Barbara Burroni, Isabelle Dusanter-Fourt, Ismael Boussaid, Salomé Le Goff, Célia Floquet, Isabelle Hatin
Publikováno v: Haematologica
Haematologica, Ferrata Storti Foundation, 2020, ⟨10.3324/haematol.2019.239970⟩
Haematologica, 2020, ⟨10.3324/haematol.2019.239970⟩
In ribosomopathies, the Diamond-Blackfan anemia (DBA) or 5q- syndrome, ribosomal protein (RP) genes are affected by mutation or deletion, resulting in bone marrow erythroid hypoplasia. Unbalanced production of ribosomal subunits leading to a limited
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e3952f914a173a95c75bac114754823
http://europepmc.org/articles/PMC7927886
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9
Lack of the multidrug transporter MRP4/ABCC4 defines the PEL-negative blood group and impairs platelet aggregation
Autor: Gaël Nicolas, Thierry Peyrard, Mahmoud Mikdar, Slim Azouzi, Patrick Mayeux, Christine Bole-Feysot, Alexandra Willemetz, Olivier Hermine, Cédric Vrignaud, Marc Cloutier, Emilie-Fleur Gautier, Alexandre Raneri, Virginie Salnot, Maryse St-Louis, Caroline Le Van Kim, Jessica Constanzo-Yanez, Jean-Pierre Cartron, Gabriele Jedlitschky, Nancy Robitaille, Carole Éthier, Patricia Hermand, Patrick Nitschke, Yves Colin
Publikováno v: Blood
Blood, 2019, 135 (6), pp.441-448. ⟨10.1182/blood.2019002320⟩
Blood, American Society of Hematology, 2019, 135 (6), pp.441-448. ⟨10.1182/blood.2019002320⟩
The rare PEL-negative phenotype is one of the last blood groups with an unknown genetic basis. By combining whole-exome sequencing and comparative global proteomic investigations, we found a large deletion in the ABCC4/MRP4 gene encoding an ATP-bindi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50d4a2aff9bf7da7bca50bd629f81f21
https://doi.org/10.1182/blood.2019002320
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10
Role of Caspase-10-P13tBID axis in erythropoiesis regulation
Autor: Mathilde Lamarque, Emilie-Fleur Gautier, François Rodrigues, Flavia Guillem, Elisa Bayard, Cédric Broussard, Thiago Maciel Trovati, Jean-Benoît Arlet, Patrick Mayeux, Olivier Hermine, Geneviève Courtois
Publikováno v: Cell death and differentiation.
Red blood cell production is negatively controlled by the rate of apoptosis at the stage of CFU-E/pro-erythroblast differentiation, depending on the balance between erythropoietin (EPO) levels and activation of the Fas/FasL pathway. At this stage, ac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac796f8947179ac8041249ed78968f58
https://pubmed.ncbi.nlm.nih.gov/36202990
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