VC1 catalyses a key step in the biosynthesis of vicine in faba bean

Autor: Wei Chang, Jens Stougaard, Emilie Björnsdotter, Hamid Khazaei, Frederick L. Stoddard, Rebecca Tacke, Marcin Nadzieja, Albert Vandenberg, Leandro Escobar-Herrera, Xinxing Xia, Alan H. Schulman, Donal M. O'Sullivan, Stig U. Andersen, Christoph Crocoll, Davide Mancinotti, Deepti Angra, Fernando Geu-Flores, Wolfgang Link

Publikováno v: Björnsdotter, E, Nadzieja, M, Chang, W, Escobar-Herrera, L, Mancinotti, D, Angra, D, Xia, X, Tacke, R, Khazaei, H, Crocoll, C, Vandenberg, A, Link, W, Stoddard, F L, O'Sullivan, D M, Stougaard, J, Schulman, A H, Andersen, S U & Geu-Flores, F 2021, ' VC1 catalyses a key step in the biosynthesis of vicine in faba bean ', Nature Plants, vol. 7, pp. 923–931 . https://doi.org/10.1038/s41477-021-00950-w
Björnsdotter, E, Nadzieja, M, Chang, W, Escobar-Herrera, L, Mancinotti, D, Angra, D, Xia, X, Tacke, R, Khazaei, H, Crocoll, C, Vandenberg, A, Link, W, Stoddard, F L, O'Sullivan, D M, Stougaard, J, Schulman, A H, Andersen, S U & Geu-Flores, F 2021, ' VC1 catalyses a key step in the biosynthesis of vicine in faba bean ', Nature Plants, vol. 7, no. 7, pp. 923-931 . https://doi.org/10.1038/s41477-021-00950-w
Nature plants

Faba bean (Vicia faba L.) is a widely adapted and high-yielding legume cultivated for its protein-rich seeds(1). However, the seeds accumulate the pyrimidine glucosides vicine and convicine, which can cause haemolytic anaemia (favism) in 400 million

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