Výsledky vyhledávání - "Emilie Bizard"

New Nitric Oxide Donor NCX 1443: Therapeutic Effects on Pulmonary Hypertension in the SAD Mouse Model of Sickle Cell Disease

Autor: Aurélien Parpaleix, Shariq Abid, Kanny Kebe, Claire-Marie Tissot, Marielle Breau, Serge Adnot, Amal Houssaini, Françoise Tomberli, Bernard Maitre, Geneviève Derumeaux, Elena Bastia, Larissa Lipskaia, Emilie Bizard, Armand Mekontso-Dessap, Elisabeth Marcos

Publikováno v: Journal of Cardiovascular Pharmacology. 71:283-292

Nitric oxide (NO) donors may be useful for treating pulmonary hypertension (PH) complicating sickle cell disease (SCD), as endogenous NO is inactivated by hemoglobin released by intravascular hemolysis. Here, we investigated the effects of the new NO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eabbb5a8cb81a5b6dd4cf6cf70385ac3
https://doi.org/10.1097/fjc.0000000000000570

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Smoking, telomere length and lung function decline: a longitudinal population-based study

Autor: Laurent Boyer, Bénédicte Leynaert, Pascal Demoly, Jorge Boczkowski, Serge Adnot, Isabelle Pin, Deborah Jarvis, Pascal Andujar, Catherine Neukirch, Emilie Bizard, Gabriel Thabut, Dominique Courbon, Elisabeth Marcos

Publikováno v: Thorax
Thorax, BMJ Publishing Group, 2018, 73 (3), pp.283-285. ⟨10.1136/thoraxjnl-2017-210294⟩

Telomere shortening is associated with COPD and impaired lung function in cross-sectional studies, but there is no longitudinal study. We used data from 448 participants recruited as part of the French follow-up of the European Community Respiratory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad9f02ce6ca76343573bd35470612377
http://hdl.handle.net/10044/1/51804

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Targeting the mTOR signaling pathway to inhibit lung cell senescence in COPD

Autor: Shariq Abid, Elisabeth Marcos, Kanny Kebe, Silke Meiners, Dominique Rideau, Jin Huang, Aya Attwe, Marielle Breau, Amal Houssaini, Emilie Bizard, Pierre Validire, Valerie Amsellem, Bernard Maitre, Serge Adnot

Publikováno v: 3.3 Mechanisms of Lung Injury and Repair.

Cell senescence, defined as a stable cell-cycle arrest combined with stereotyped phenotypic changes, might play a causal role in COPD. We previously reported that senescent cells are increased in lungs from patients with COPD and express a robust sen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f8552a67de4590e363dcea8e1d4248ad
https://doi.org/10.1183/13993003.congress-2016.pa4024

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Telomere Shortening in Middle-Aged Men with Sleep-disordered Breathing

Autor: Jorge Boczkowski, Ala Covali-Noroc, Xavier Drouot, Isabelle Macquin-Mavier, Laurent Boyer, Etienne Audureau, Geneviève Derumeaux, Philippe Le Corvoisier, Serge Adnot, Laurent Margarit, Emilie Bizard, Sylvie Bastuji-Garin, Elisabeth Marcos, Thibaud Damy

Publikováno v: Annals of the American Thoracic Society
Annals of the American Thoracic Society, American Thoracic Society, 2016, 13 (7), pp.1136-1143. ⟨10.1513/AnnalsATS.201510-718OC⟩
ResearcherID

International audience; Rationale: Sleep disorders may lead to stress-induced premature aging and telomere shortening.Objectives: To determine whether obstructive sleep apnea syndrome causing intermittent hypoxemic episodes was associated with telome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5301346cf343a43157b6236bf3ca5ddb
https://pubmed.ncbi.nlm.nih.gov/27163410

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Harmonin-b, an actin-binding scaffold protein, is involved in the adaptation of mechanoelectrical transduction by sensory hair cells

Autor: Elisa Caberlotto, Jean-Yves Tinevez, Christine Petit, Christophe Houbron, Guy P. Richardson, Emilie Bizard, Pascal Martin, Vincent Michel, Nicolas Michalski, Alexander F. J. van Aken, Gaelle M. Lefèvre, Jean-Pierre Hardelin, Corné J. Kros, Dominique Weil

Publikováno v: Pflügers Archiv European Journal of Physiology
Pflügers Archiv European Journal of Physiology, Springer Verlag, 2009, 459 (1), pp.115-130. ⟨10.1007/s00424-009-0711-x⟩
Pflügers Archiv European Journal of Physiology, 2009, 459 (1), pp.115-130. ⟨10.1007/s00424-009-0711-x⟩
Pflugers Archiv

We assessed the involvement of harmonin-b, a submembranous protein containing PDZ domains, in the mechanoelectrical transduction machinery of inner ear hair cells. Harmonin-b is located in the region of the upper insertion point of the tip link that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a30170a16182dc70326ed67813e5e6f4
https://doi.org/10.1007/s00424-009-0711-x

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A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth

Autor: Léa Lepelletier, Dominique Weil, Vincent Michel, Christine Petit, Jean-Pierre Hardelin, Gaelle M. Lefèvre, Uwe Wolfrum, Emilie Bizard

Publikováno v: Development. 135:1427-1437

The planar polarity and staircase-like pattern of the hair bundle are essential to the mechanoelectrical transduction function of inner ear sensory cells. Mutations in genes encoding myosin VIIa, harmonin, cadherin 23,protocadherin 15 or sans cause U

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c16e44e2c4b5e8190b98565dfdcb3c
https://doi.org/10.1242/dev.012922

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