Data from A Major Role for Mitotic cdc2 Kinase Inactivation in the Establishment of the Mitotic DNA Damage Checkpoint

Autor: Mounira Amor-Guéret, Rosine Onclercq-Delic, Serge Leibovitch, Olga Grigorieva, Emilie Bayart

Cdc2 kinase is inactivated when DNA damage occurs during the spindle assembly checkpoint. Here, we show that the level of mitotic Bloom syndrome protein phosphorylation reflects the level of cdc2 activity. A complete inactivation of cdc2 by either in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bb3e54d8b6e7abb82489dd7faeaca76
https://doi.org/10.1158/0008-5472.c.6493985.v1

Dosimetric characterisation and application to radiation biology of a kHz laser-driven electron beam

Autor: Aline Vernier, Rachel Delorme, Patrik Gonçalves Jorge, Lucas Rovige, M. Cavallone, Raphaël Moeckli, Emilie Bayart, Jérôme Faure, Eric Deutsch, Alessandro Flacco, Julius Huijts

Publikováno v: Appl.Phys.B
Appl.Phys.B, 2021, 127 (4), pp.57. ⟨10.1007/s00340-021-07610-z⟩
Applied Physics B, vol. 127, no. 4

International audience; Laser-plasma accelerators can produce ultra-short electron bunches in the femtosecond to picosecond duration range, resulting in very high peak dose rates in comparison with clinical accelerators. This unique characteristic mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeae0bc49cac295b732a6ba6571b46c9
https://hal.archives-ouvertes.fr/hal-03086787

Enhancement of IUdR Radiosensitization by Low-Energy Photons Results from Increased and Persistent DNA Damage

Autor: Jonathan Dadoun, Jean Bourhis, Eric Deutsch, L. Calmels, Fabien Allot, Marc Denoziere, Johann Plagnard, Frederic Pouzoulet, Emilie Bayart, Jean-Luc Ravanat, André Bridier

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2017, 12 (1), pp.168395-168395. 〈10.1371/journal.pone.0168395〉
PLoS ONE, Vol 12, Iss 1, p e0168395 (2017)
PLoS ONE, 2017, 12 (1), pp.168395-168395; e0168395. ⟨10.1371/journal.pone.0168395⟩
PLoS ONE, Public Library of Science, 2017, 12 (1), pp.168395-168395; e0168395. ⟨10.1371/journal.pone.0168395⟩
PloS one, vol. 12, no. 1, pp. e0168395

International audience; Low-energy X-rays induce Auger cascades by photoelectric absorption in iodine present in the DNA of cells labeled with 5-iodo-2'-deoxyuridine (IUdR). This photoactivation therapy results in enhanced cellular sensitivity to rad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5727daa181ad4b892eebe25021eb40e8
https://hal.archives-ouvertes.fr/hal-01692978

Topoisomerase IIIa is required for normal proliferation and telomere stability in alternative lenghtening of telomeres

Autor: Eric Gilson, Emilie Bayart, Lionel Guittat, Arturo Londoño-Vallejo, Marie-Josèphe Giraud-Panis, Thomas Wenner, Jean-François Riou, Mounira Amor-Guéret, Nassima Temime-Smaali, Dennis Gomez, Céline Douarre

Publikováno v: EMBO Journal
EMBO Journal, EMBO Press, 2008, 27, pp.1513-1524. ⟨10.1038/emboj.2008.74⟩
EMBO Journal, 2008, 27, pp.1513-1524. ⟨10.1038/emboj.2008.74⟩

Topoisomerase (Topo) IIIalpha associates with BLM helicase, which is proposed to be important in the alternative lengthening of telomeres (ALT) pathway that allows telomere recombination in the absence of telomerase. Here, we show that human Topo III

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::600760d5a51641cf0f47058e3912bf61
https://hal.archives-ouvertes.fr/hal-00374479