Výsledky vyhledávání - "Emilie Ansciaux"

Validation by Magnetic Resonance Imaging of the Diagnostic Potential of a Heptapeptide-Functionalized Imaging Probe Targeted to Amyloid-β and Able to Cross the Blood-Brain Barrier

Autor: Elamine Saidi, Lionel Larbanoix, Séverine Andre, Sophie Laurent, Luce Vander Elst, Emilie Ansciaux, Dimitri Stanicki, Carmen Burtea, Denis Nonclercq, Robert N. Muller

Publikováno v: Journal of Alzheimer's Disease. 60:1547-1565

The diagnosis of Alzheimer's disease (AD) is a critical step in the management of patients. We have developed a non-invasive diagnosis tool based on magnetic resonance molecular imaging (MRMI) of amyloid-β peptide using ultra-small particles of iron

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1691249b666f231de8d15e404ea2771
https://doi.org/10.3233/jad-170563

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Design and evaluation of a 6-mer amyloid-beta protein derived phage display library for molecular targeting of amyloid plaques in Alzheimer's disease: Comparison with two cyclic heptapeptides derived from a randomized phage display library

Autor: Sophie Laurent, Lionel Larbanoix, Carmen Burtea, Emilie Ansciaux, Isabelle Mahieu, Luce Vander Elst, Robert N. Muller

Publikováno v: Peptides. 32:1232-1243

Amyloid plaques are the main molecular hallmark of Alzheimer's disease. Specific carriers are needed for molecular imaging and for specific drug delivery. In order to identify new low molecular weight amyloid plaque-specific ligands, the phage displa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d057cd7abe58e7c6951d88a2ebc21d
https://doi.org/10.1016/j.peptides.2011.04.026

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In vitro and in vivo characterization of several functionalized ultrasmall particles of iron oxide, vectorized against amyloid plaques and potentially able to cross the blood-brain barrier: toward earlier diagnosis of Alzheimer's disease by molecular imaging

Autor: Sophie Laurent, Luce Vander Elst, Déborah Crombez, Denis Nonclercq, Robert N. Muller, Carmen Burtea, Emilie Ansciaux

Publikováno v: Contrast mediamolecular imaging. 10(3)

Alzheimer's disease (AD) is a neurodegenerative disorder most often diagnosed 10 years after its onset and development. It is characterized by the accumulation of amyloid-β peptide (ABP) into amyloid plaques between nerve cells, which produces a mas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d5a7337570be1f9e9a1a24442ee6596
https://pubmed.ncbi.nlm.nih.gov/25284012

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