Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Emilie, Ceraudo"'
Autor:
Jordan M. Mattheisen, Chris Limberakis, Roger B. Ruggeri, Matthew S. Dowling, Christopher W. am Ende, Emilie Ceraudo, Thomas Huber, Christopher L. McClendon, Thomas P. Sakmar
Publikováno v:
Journal of the American Chemical Society. 145:11173-11184
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cc5b00c6a565fcfee5f02177fdc5ebb
https://doi.org/10.1021/jacs.3c00972
https://doi.org/10.1021/jacs.3c00972
Autor:
Yu Chen, Ping Chi, Thomas Huber, Thomas P. Sakmar, Barry S. Taylor, Matthew T. Chang, Juliet Chen, Youxin Guan, Jasmine H. Francis, Alexander N. Shoushtari, Mohini R. Pachai, Naitao Wang, Ruobing Jia, Cindy Lee, Amanda R. Moore, Emilie Ceraudo, Gabriella Bayshtok, Tyler D. Hitchman
Purpose:All uveal melanoma and a fraction of other melanoma subtypes are driven by activation of the G-protein alpha-q (Gαq) pathway. Targeting these melanomas has proven difficult despite advances in the molecular understanding of key driver signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5081a528234de947ebc82cb311f8ab41
https://doi.org/10.1158/1078-0432.c.6530301
https://doi.org/10.1158/1078-0432.c.6530301
Autor:
Yu Chen, Ping Chi, Thomas Huber, Thomas P. Sakmar, Barry S. Taylor, Matthew T. Chang, Juliet Chen, Youxin Guan, Jasmine H. Francis, Alexander N. Shoushtari, Mohini R. Pachai, Naitao Wang, Ruobing Jia, Cindy Lee, Amanda R. Moore, Emilie Ceraudo, Gabriella Bayshtok, Tyler D. Hitchman
Supplementary figures S1-S6 with figure legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce8efd4e6384fb453406751fddbe584
https://doi.org/10.1158/1078-0432.22479795.v1
https://doi.org/10.1158/1078-0432.22479795.v1
Autor:
Yu Chen, Ping Chi, Thomas Huber, Thomas P. Sakmar, Barry S. Taylor, Matthew T. Chang, Juliet Chen, Youxin Guan, Jasmine H. Francis, Alexander N. Shoushtari, Mohini R. Pachai, Naitao Wang, Ruobing Jia, Cindy Lee, Amanda R. Moore, Emilie Ceraudo, Gabriella Bayshtok, Tyler D. Hitchman
raw uncropped labeled western blots
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3664900e14a101e3af47e3c9420a7341
https://doi.org/10.1158/1078-0432.22479798
https://doi.org/10.1158/1078-0432.22479798
Autor:
Ilana B. Kotliar, Emilie Ceraudo, Kevin Kemelmakher-Liben, Deena A. Oren, Emily Lorenzen, Tea Dodig-Crnković, Mizuho Horioka-Duplix, Thomas Huber, Jochen M. Schwenk, Thomas P. Sakmar
Cholestatic itch is a severe and debilitating symptom in liver diseases with limited treatment options. The class A G protein-coupled receptor (GPCR) Mas-related GPCR subtype X4 (MRGPRX4) has been identified as a receptor for bile acids, which are po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea545bcb14d10447ee8ac84af1e9e567
https://doi.org/10.1101/2022.12.06.519316
https://doi.org/10.1101/2022.12.06.519316
Autor:
Gabriella Bayshtok, Matthew T. Chang, Amanda R. Moore, Tyler D. Hitchman, Emilie Ceraudo, Youxin Guan, Cindy Lee, Thomas P. Sakmar, Ruobing Jia, Alexander N. Shoushtari, Jasmine H. Francis, Ping Chi, Mohini R. Pachai, Juliet Chen, Thomas Huber, Barry S. Taylor, Naitao Wang, Yu Chen
Publikováno v:
Clinical Cancer Research. 27:1476-1490
Purpose: All uveal melanoma and a fraction of other melanoma subtypes are driven by activation of the G-protein alpha-q (Gαq) pathway. Targeting these melanomas has proven difficult despite advances in the molecular understanding of key driver signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47948887edc1ae4f404214233bfd697f
https://doi.org/10.1158/1078-0432.ccr-20-2860
https://doi.org/10.1158/1078-0432.ccr-20-2860
Autor:
Ilana B. Kotliar, Emilie Ceraudo, Kevin Kemelmakher-Liben, Deena A. Oren, Emily Lorenzen, Tea Dodig-Crnković, Mizuho Horioka-Duplix, Thomas Huber, Jochen M. Schwenk, Thomas P. Sakmar
Publikováno v:
Journal of Biological Chemistry. 299:104664
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4898d023310b7e03c05fff9a57cd667a
https://doi.org/10.1016/j.jbc.2023.104664
https://doi.org/10.1016/j.jbc.2023.104664
Publikováno v:
Cellular and Molecular Neurobiology. 41:1085-1101
Many G protein-coupled receptors (GPCRs) signal through more than one subtype of heterotrimeric G proteins. For example, the C–C chemokine receptor type 5 (CCR5), which serves as a co-receptor to facilitate cellular entry of human immunodeficiency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59f68312ee5f993b83f499e6c8a7f231
https://doi.org/10.1007/s10571-020-01002-1
https://doi.org/10.1007/s10571-020-01002-1
Autor:
Tyler D, Hitchman, Gabriella, Bayshtok, Emilie, Ceraudo, Amanda R, Moore, Cindy, Lee, Ruobing, Jia, Naitao, Wang, Mohini R, Pachai, Alexander N, Shoushtari, Jasmine H, Francis, Youxin, Guan, Juliet, Chen, Matthew T, Chang, Barry S, Taylor, Thomas P, Sakmar, Thomas, Huber, Ping, Chi, Yu, Chen
Publikováno v:
Clin Cancer Res
Most uveal melanomas harbor mutations in Gαq and show constitutive MAPK activation. Although MEK inhibition has some efficacy against uveal melanoma, clinical responses are typically poor. The Gαq inhibitor-MEK inhibitor combination showed prolonge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e16455d44d09e19f6e5698ab8f4d9212
https://pubmed.ncbi.nlm.nih.gov/33355300
https://pubmed.ncbi.nlm.nih.gov/33355300
Publikováno v:
Cellular and Molecular Neurobiology
Many G protein-coupled receptors (GPCRs) signal through more than one subtype of heterotrimeric G proteins. For example, the C–C chemokine receptor type 5 (CCR5), which serves as a co-receptor to facilitate cellular entry of human immunodeficiency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2f6a5c191b7dc5969b92f7ff964020ac
https://pubmed.ncbi.nlm.nih.gov/33216235
https://pubmed.ncbi.nlm.nih.gov/33216235