Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Emiliano Zamponi"'
Autor:
Daniel M. Virga, Stevie Hamilton, Bertha Osei, Abigail Morgan, Parker Kneis, Emiliano Zamponi, Natalie J. Park, Victoria L. Hewitt, David Zhang, Kevin C. Gonzalez, Fiona M. Russell, D. Grahame Hardie, Julien Prudent, Erik Bloss, Attila Losonczy, Franck Polleux, Tommy L. Lewis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Neuronal mitochondria play important roles beyond ATP generation, including Ca2+ uptake, and therefore have instructive roles in synaptic function and neuronal response properties. Mitochondrial morphology differs significantly between the a
Externí odkaz:
https://doaj.org/article/4622b875797a4a148a830a6b459942d0
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Evidence from models and experiments suggests that the networked structure observed in mitochondria emerges at the critical point of a phase transition controlled by fission and fusion rates. If mitochondria are poised at criticality, the re
Externí odkaz:
https://doaj.org/article/fbe5f63380204117a574c1b557b7ebf6
Autor:
Emiliano Zamponi, Gustavo F. Pigino
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Histopathological studies revealed that progressive neuropathies including Alzheimer, and Prion diseases among others, include accumulations of misfolded proteins intracellularly, extracellularly, or both. Experimental evidence suggests that among th
Externí odkaz:
https://doaj.org/article/79980b753b6c4954aace9beec5c7d244
Autor:
Emiliano Zamponi, Fiamma Buratti, Gabriel Cataldi, Hector Hugo Caicedo, Yuyu Song, Lisa M Jungbauer, Mary J LaDu, Mariano Bisbal, Alfredo Lorenzo, Jiyan Ma, Pablo R Helguera, Gerardo A Morfini, Scott T Brady, Gustavo F Pigino
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188340 (2017)
Prion diseases include a number of progressive neuropathies involving conformational changes in cellular prion protein (PrPc) that may be fatal sporadic, familial or infectious. Pathological evidence indicated that neurons affected in prion diseases
Externí odkaz:
https://doaj.org/article/9ec8a9f6cfde4b63934a882da4ebbb3c
Autor:
Daniel M. Virga, Stevie Hamilton, Bertha Osei, Abigail Morgan, Emiliano Zamponi, Natalie J. Park, Victoria L. Hewitt, David Zhang, Kevin C. Gonzalez, Erik Bloss, Franck Polleux, Tommy L. Lewis
Publikováno v:
bioRxiv
Neuronal mitochondria play important roles beyond ATP generation, including Ca2+uptake, and therefore have instructive roles in synaptic function and neuronal response properties. Mitochondrial morphology differs significantly in the axon and dendrit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd4a5b0ecfd4df1eab895925a61d7919
https://doi.org/10.1101/2023.03.25.534233
https://doi.org/10.1101/2023.03.25.534233
Autor:
Gustavo Pigino, Emiliano Zamponi
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Frontiers in Cellular Neuroscience
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Frontiers in Cellular Neuroscience
Histopathological studies revealed that progressive neuropathies including Alzheimer, and Prion diseases among others, include accumulations of misfolded proteins intracellularly, extracellularly, or both. Experimental evidence suggests that among th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97de8363c8e98f1fc82351f8d2a9fe30
https://www.frontiersin.org/article/10.3389/fncel.2019.00350/full
https://www.frontiersin.org/article/10.3389/fncel.2019.00350/full
Autor:
Pablo Helguera, Orlando V. Billoni, Sergio A. Cannas, Nahuel Zamponi, Dante R. Chialvo, Emiliano Zamponi
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Mitochondrial networks exhibit a variety of complex behaviors, including coordinated cell-wide oscillations of energy states as well as a phase transition (depolarization) in response to oxidative stress. Since functional and structural properties ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b4c170ea0efcdbf96f1c656ea140dc5
http://www.nature.com/articles/s41598-017-18351-5
http://www.nature.com/articles/s41598-017-18351-5
Autor:
Emiliano Zamponi, Pablo Helguera
Publikováno v:
Developmental neurobiologyREFERENCES. 79(7)
Oxidative stress (OS) and mitochondrial dysfunction (MD) have been extensively studied and defined as therapeutic targets in Down syndrome (DS). Though originally associated to individual genes located in supernumerary chromosome 21, OS and MD metabo
Autor:
Pinar Coskun, Sergio A. Cannas, Emiliano Zamponi, Nahuel Zamponi, Pablo Helguera, Alfredo Lorenzo, Jorge Busciglio, Gonzalo Quassollo, Katheleen Gardiner, Gustavo Pigino, Dante R. Chialvo
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Zamponi, Emiliano; Zamponi, Nahuel; Coskun, Pinar; Quassollo, Gonzalo; Lorenzo, Alfredo; Cannas, Sergio A; et al.(2018). Nrf2 stabilization prevents critical oxidative damage in Down syndrome cells.. Aging Cell, 17(5), e12812. doi: 10.1111/acel.12812. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8m88h0wf
Aging Cell
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Zamponi, Emiliano; Zamponi, Nahuel; Coskun, Pinar; Quassollo, Gonzalo; Lorenzo, Alfredo; Cannas, Sergio A; et al.(2018). Nrf2 stabilization prevents critical oxidative damage in Down syndrome cells.. Aging Cell, 17(5), e12812. doi: 10.1111/acel.12812. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8m88h0wf
Aging Cell
Mounting evidence implicates chronic oxidative stress as a critical driver of the aging process. Down syndrome (DS) is characterized by a complex phenotype, including early senescence. DS cells display increased levels of reactive oxygen species (ROS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b894ecceb0cb89ba5e91dc15fc467058
Wiley Online Library
Wiley Online Library
Autor:
Emiliano Zamponi, Gonzalo F. Mayol, Adriana Lanfredi-Rangel, Staffan G. Svärd, Nahuel Zamponi, María C. Touz
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Our understanding of protein and lipid trafficking in eukaryotic cells has been challenged by the finding of different forms of compartmentalization and cargo processing in protozoan parasites. Here, we show that, in the absence of a Golgi compartmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23bb625f99f1dd48ce0a74fece33c15e
Wiley Online Library
Wiley Online Library