Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Emiliano P, Ricci"'
Autor:
Alexandre Legrand, Clara Dahoui, Clément De La Myre Mory, Kodie Noy, Laura Guiguettaz, Margaux Versapuech, Clara Loyer, Margaux Pillon, Mégane Wcislo, Laurent Guéguen, Clarisse Berlioz-Torrent, Andrea Cimarelli, Mathieu Mateo, Francesca Fiorini, Emiliano P Ricci, Lucie Etienne
Publikováno v:
PLoS Biology, Vol 22, Iss 7, p e3002696 (2024)
Sterile alpha motif domain-containing proteins 9 and 9-like (SAMD9/9L) are associated with life-threatening genetic diseases in humans and are restriction factors of poxviruses. Yet, their cellular function and the extent of their antiviral role are
Externí odkaz:
https://doaj.org/article/c39eeadc03794b0bb1ab81f16caf21dd
Autor:
Manon Venet, Margarida Sa Ribeiro, Elodie Décembre, Alicia Bellomo, Garima Joshi, Célia Nuovo, Marine Villard, David Cluet, Magali Perret, Rémi Pescamona, Helena Paidassi, Thierry Walzer, Omran Allatif, Alexandre Belot, Sophie Trouillet-Assant, Emiliano P. Ricci, Marlène Dreux
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Plasmacytoid DC (pDC) have been shown to secrete type I IFN and to be involved in controlling replication and spread of some viruses. Here the authors show that in severe SARS-CoV-2 infection pDC function is impaired leading to reduced type I IFN pro
Externí odkaz:
https://doaj.org/article/04fff4c178eb439c8dc6ad978ab2f441
Autor:
Sébastien Durand, Marion Bruelle, Fleur Bourdelais, Bigitha Bennychen, Juliana Blin-Gonthier, Caroline Isaac, Aurélia Huyghe, Sylvie Martel, Antoine Seyve, Christophe Vanbelle, Annie Adrait, Yohann Couté, David Meyronet, Frédéric Catez, Jean-Jacques Diaz, Fabrice Lavial, Emiliano P. Ricci, François Ducray, Mathieu Gabut
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Pluripotency is coordinated at multiple levels of gene expression. Here the authors show that ribosome biogenesis is tightly regulated in embryonic stem cells (ESC) to control the translation of transcription and chromatin factors and dictate ESC fat
Externí odkaz:
https://doaj.org/article/a21afed10321427a82d524a32c704e2c
Autor:
Yu H. Sun, Ruoqiao Huiyi Wang, Khai Du, Jiang Zhu, Jihong Zheng, Li Huitong Xie, Amanda A. Pereira, Chao Zhang, Emiliano P. Ricci, Xin Zhiguo Li
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Ribosome can mediate piRNA biogenesis from long non-coding RNAs following translation of the short open reading frames. Here the authors show that 80S ribosome also guides piRNA production from 3’ UTR of protein-coding genes after translation of lo
Externí odkaz:
https://doaj.org/article/1047700fa4bf4ac1a2142ef7cbfd7f46
Autor:
Mehdi Eshraghi, Pabalu P. Karunadharma, Juliana Blin, Neelam Shahani, Emiliano P. Ricci, Audrey Michel, Nicolai T. Urban, Nicole Galli, Manish Sharma, Uri Nimrod Ramírez-Jarquín, Katie Florescu, Jennifer Hernandez, Srinivasa Subramaniam
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Huntington disease (HD) is a neurodegenerative disorder caused by the expansion of a polyglutamine tract in the huntingtin (mHtt) protein. Here the authors suggest that mHtt promotes ribosome stalling and inhibits protein synthesis.
Externí odkaz:
https://doaj.org/article/a00d7181daf04071b4b42dae11f057fa
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Innate immunity is the frontline of defense against infections and tissue damage. It is a fast and semi-specific response involving a myriad of processes essential for protecting the organism. These reactions promote the clearance of danger by activa
Externí odkaz:
https://doaj.org/article/d00a00a9119c4078b6dc6543f332f5d9
Autor:
Philippe E. Mangeot, Valérie Risson, Floriane Fusil, Aline Marnef, Emilie Laurent, Juliana Blin, Virginie Mournetas, Emmanuelle Massouridès, Thibault J. M. Sohier, Antoine Corbin, Fabien Aubé, Marie Teixeira, Christian Pinset, Laurent Schaeffer, Gaëlle Legube, François-Loïc Cosset, Els Verhoeyen, Théophile Ohlmann, Emiliano P. Ricci
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
A current challenge in genome editing is delivering Cas9 and sgRNA into target cells. Here the authors engineer a delivery system based on murine leukemia virus-like particles loaded with Cas9-sgRNA ribonucleoproteins to induce efficient genome editi
Externí odkaz:
https://doaj.org/article/0bd13889c5db4e0ba26c33892287ae45
Autor:
Alejandra Gutierrez-Guerrero, Maria Jimena Abrey Recalde, Philippe E. Mangeot, Caroline Costa, Ornellie Bernadin, Séverine Périan, Floriane Fusil, Gisèle Froment, Adriana Martinez-Turtos, Adrien Krug, Francisco Martin, Karim Benabdellah, Emiliano P. Ricci, Simone Giovannozzi, Rik Gijsbers, Eduard Ayuso, François-Loïc Cosset, Els Verhoeyen
Publikováno v:
Frontiers in Genome Editing, Vol 3 (2021)
Programmable nucleases have enabled rapid and accessible genome engineering in eukaryotic cells and living organisms. However, their delivery into human blood cells can be challenging. Here, we have utilized “nanoblades,” a new technology that de
Externí odkaz:
https://doaj.org/article/1d5485f02cd64cd39b1ee599b28883bf
Publikováno v:
PLoS Biology, Vol 18, Iss 12, p e3000969 (2020)
Pathogens such as Pseudomonas aeruginosa advantageously modify animal host physiology, for example, by inhibiting host protein synthesis. Translational inhibition of insects and mammalian hosts by P. aeruginosa utilizes the well-known exotoxin A effe
Externí odkaz:
https://doaj.org/article/d7afeeb9e853428694912bb19ff89b38
Autor:
Eléonore Pérès, Juliana Blin, Emiliano P Ricci, Maria Artesi, Vincent Hahaut, Anne Van den Broeke, Antoine Corbin, Louis Gazzolo, Lee Ratner, Pierre Jalinot, Madeleine Duc Dodon
Publikováno v:
PLoS Pathogens, Vol 14, Iss 3, p e1006933 (2018)
Human T-cell leukemia virus type 1 (HTLV-1) is the etiological agent of adult T-cell leukemia/lymphoma (ATLL), an aggressive malignant proliferation of activated CD4+ T lymphocytes. The viral Tax oncoprotein is critically involved in both HTLV-1-repl
Externí odkaz:
https://doaj.org/article/b33d76150be5483dae7b901fa4bea860