Circulating levels of IL-1 family cytokines and receptors in Alzheimer’s disease: new markers of disease progression?

Autor: Paola Italiani, Ilaria Puxeddu, Sabrina Napoletano, Emanuele Scala, Daniela Melillo, Simone Manocchio, Antonella Angiolillo, Paola Migliorini, Diana Boraschi, Emilia Vitale, Alfonso Di Costanzo

Publikováno v: Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-12 (2018)

Abstract Background Although the mechanisms underlying AD neurodegeneration are not fully understood, it is now recognised that inflammation could play a crucial role in the initiation and progression of AD neurodegeneration. A neuro-inflammatory net

Externí odkaz: https://doaj.org/article/714a5ea38d1e497a824d461fa8cd3023

Variants of ST8SIA1 are associated with risk of developing multiple sclerosis.

Autor: Seema Husain, Cagri Yildirim-Toruner, Justin P Rubio, Judith Field, Southern MS Genetics Consortium, Marvin Schwalb, Stuart Cook, Marcella Devoto, Emilia Vitale

Publikováno v: PLoS ONE, Vol 3, Iss 7, p e2653 (2008)

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system of unknown etiology with both genetic and environmental factors playing a role in susceptibility. To date, the HLA DR15/DQ6 haplotype within the major hist

Externí odkaz: https://doaj.org/article/29284e3ed38c4bfcacc9da58ad36dced

CD33 and SIGLECL1 Immunoglobulin Superfamily Involved in Dementia

Autor: Massimiliano Caiazzo, Sabina Pappatà, Emilia Vitale, Alfonso Di Costanzo, Aldo Donizetti, Graziella Milan, Antonella Angiolillo, Raffaele Ferrari, Francesca Saveria Tripodi, Alfredo Postiglione, Laura Fucci, Antonella Rendina, Denise Drongitis, Francesca Giustezza, Paola Bossù

Publikováno v: Journal of neuropathology and experimental neurology 79 (2020): 891–901. doi:10.1093/jnen/nlaa055
info:cnr-pdr/source/autori:Rendina, Antonella; Drongitis, Denise; Donizetti, Aldo; Fucci, Laura; Milan, Graziella; Tripodi, Francesca; Giustezza, Francesca; Postiglione, Alfredo; Pappata, Sabina; Ferrari, Raffaele; Bossu, Paola; Angiolillo, Antonella; di Costanzo, Alfonso; Caiazzo, Massimiliano; Vitale, Emilia/titolo:CD33 and SIGLECL1 Immunoglobulin Superfamily Involved in Dementia/doi:10.1093%2Fjnen%2Fnlaa055/rivista:Journal of neuropathology and experimental neurology/anno:2020/pagina_da:891/pagina_a:901/intervallo_pagine:891–901/volume:79
Journal of Neuropathology and Experimental Neurology, 79(8), 891. Lippincott Williams and Wilkins

Sialic acid-binding immunoglobulin-type lectins, which are predominantly expressed in immune cells, represent a family of immunomodulatory receptors with inhibitory and activating signals, in both healthy and disease states. Genetic factors are impor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ca13ba03f055f11ab4fefc56d7c845a
http://hdl.handle.net/11588/825478

Levels Of Interleukins In The Serum Of Patients With Or At Risk Of Alzheimer’s Disease

Autor: Angiolillo, Antonella, Simone, Manocchio, Paola, Italiani, Ilaria, Puxeddu, Sabrina, Napoletano, Daniela, Melillo, Dudiez, Salvatore, Paola, Migliorini, Diana, Boraschi, Emilia, Vitale, DI COSTANZO, Alfonso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3981::ee420ce871f9baf3347b2919fd21b0d7
http://hdl.handle.net/11695/81818

GRN deletion in Familial Fronto-Temporal Dementia showing Association with clinical Variability in three familial cases

Autor: Graziella Milan, Sabrina Napoletano, Sabina Pappatà, Maria Teresa Gentile, Luca Colucci-D'Amato, Gennaro Della Rocca, Anna Maciag, Carmen Palermo Rossetti, Laura Fucci, Annibale Puca, Dario Grossi, Alfredo Postiglione, Emilia Vitale

Publikováno v: Neurobiology of aging (2017). doi:10.1016/j.neurobiolaging.2016.12.030
info:cnr-pdr/source/autori:Graziella Milan, Sabrina Napoletano, Sabina Pappatà, Maria Teresa Gentile, Luca Colucci-D'Amato, Gennaro Della Rocca, Anna Maciag, Carmen Palermo Rossetti, Laura Fucci, Annibale Puca, Dario Grossi, Alfredo Postiglione, Emilia Vitale/titolo:GRN deletion in Familial Fronto-Temporal Dementia showing Association with clinical Variability in three familial cases/doi:10.1016%2Fj.neurobiolaging.2016.12.030/rivista:Neurobiology of aging/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume

Progranulin (GRN) gene mutations have been genetically associated with FTD and are present in about 23% of patients with familial FTD. However, the neurobiology of this secreted glycoprotein remains unclear. Here, we report the identification of thre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::61151a910fed4eb662a5747f8ecaea10
https://publications.cnr.it/doc/364149