Výsledky vyhledávání - "Emilia S. Olson"

Akademický článek

Tumor Detection at 3 Tesla with an Activatable Cell Penetrating Peptide Dendrimer (ACPPD-Gd), a T1 Magnetic Resonance (MR) Molecular Imaging Agent.

Autor: Christopher D Malone, Emilia S Olson, Robert F Mattrey, Tao Jiang, Roger Y Tsien, Quyen T Nguyen

Publikováno v: PLoS ONE, Vol 10, Iss 9, p e0137104 (2015)

The ability to detect small malignant lesions with magnetic resonance imaging (MRI) is limited by inadequate accumulations of Gd with standard chelate agents. To date, no T1-targeted agents have proven superiority to Gd chelates in their ability to d

Externí odkaz: https://doaj.org/article/633d6cb8a945482bb8cca30da0b2aba0

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Molecular Imaging of the Glomerulus via Mesangial Cell Uptake of Radiolabeled Tilmanocept

Autor: Young-Hyun You, Zhengtao Qin, David R. Vera, Motoko Yanagita, Carl K. Hoh, Amin Haghighat Jahromi, Emilia S. Olson, David J. Hall, Kumar Sharma, Christopher V. Barback

Publikováno v: Journal of nuclear medicine : official publication, Society of Nuclear Medicine, vol 60, iss 9

An unmet need for the clinical management of chronic kidney disease is a predictive tool of kidney function during the first decade of the disease, when there is silent loss of glomerular function. The objective of this study was to demonstrate recep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4841ed46713f93003384f08a6a86d02
https://doi.org/10.2967/jnumed.118.223727

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Cardiac Magnetic Resonance Imaging Evaluation of Neonatal Bronchopulmonary Dysplasia-associated Pulmonary Hypertension

Autor: Jason C. Woods, David R. Spielberg, Ryan A. Moore, Emilia S. Olson, Michael D. Taylor, Robert J. Fleck, Paul S. Kingma, Paul J. Critser, Jean A. Tkach, Nara S. Higano, Sean M. Lang

Publikováno v: American Journal of Respiratory and Critical Care Medicine

Rationale: Patients with bronchopulmonary dysplasia (BPD)-associated pulmonary hypertension (PH) have increased morbidity and mortality. Noninvasive assessment relies on echocardiograms (echos), wh...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f156add2b2b786f8135c8f50cbd04c
https://pubmed.ncbi.nlm.nih.gov/31658423

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Gelatinase activity imaged by activatable cell-penetrating peptides in cell-based and in vivo models of stroke

Autor: Ming Yang, Wei Wu, Zezong Gu, Tao Jiang, Roger Y. Tsien, Lixin Ma, Jiankun Cui, Emilia S. Olson, Quanyu Cai, Shanyan Chen, J. D. Robertson, James Guthrie, Stuart A. Lipton

Publikováno v: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, vol 37, iss 1

Matrix metalloproteinases (MMPs), particularly gelatinases (MMP-2/-9), are involved in neurovascular impairment after stroke. Detection of gelatinase activity in vivo can provide insight into blood–brain barrier disruption, hemorrhage, and nerve ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b20fdde96425c0594356b9aec2db27
https://doi.org/10.1177/0271678x15621573

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Oxidative Stress: Ultrasound Detection of Regional Oxidative Stress in Deep Tissues Using Novel Enzyme Loaded Nanoparticles (Adv. Healthcare Mater. 5/2017)

Autor: Christopher D. Malone, Robert F. Mattrey, Emilia S. Olson, Sadik C. Esener, Inanc Ortac

Publikováno v: Advanced Healthcare Materials. 6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::03c596d0e2372db6f75878d330e534f4
https://doi.org/10.1002/adhm.201770026

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Neural progenitor cells labeling with microbubble contrast agent for ultrasound imaging in vivo

Autor: Emilia S. Olson, Rosemarie G. Ramirez, Marika Decyk, Robert F. Mattrey, Yuko Kono, Sidhartha Tavri, Michael Benchimol, Hong Zhang, Christopher V. Barback, Malak Itani, Wenjin Cui

Publikováno v: Biomaterials. 34:4926-4935

Tracking neuroprogenitor cells (NPCs) that are used to target tumors, infarction or inflammation, is paramount for cell-based therapy. We employed ultrasound imaging that can detect a single microbubble because it can distinguish its unique signal fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f73c6222040b312c2cb91685cc8dfab
https://doi.org/10.1016/j.biomaterials.2013.03.020

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Ultrasound Detection of Regional Oxidative Stress in Deep Tissues Using Novel Enzyme Loaded Nanoparticles

Autor: Inanc Ortac, Christopher D. Malone, Sadik C. Esener, Robert F. Mattrey, Emilia S. Olson

Publikováno v: Advanced healthcare materials. 6(5)

Oxidative stress is a powerful tool that is critical to immune mediated responses in healthy individuals, yet additionally plays a crucial role in development of cancer, inflammatory pathologies and tissue ischemia. Despite this, there remain relativ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115d768000bcbaf5549c655a28dbbf2b
https://pubmed.ncbi.nlm.nih.gov/28081299

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Tumor Detection at 3 Tesla with an Activatable Cell Penetrating Peptide Dendrimer (ACPPD-Gd), a T1 Magnetic Resonance (MR) Molecular Imaging Agent

Autor: Roger Y. Tsien, Christopher D. Malone, Emilia S. Olson, Quyen T. Nguyen, Robert F. Mattrey, Tao Jiang

Publikováno v: PloS one, vol 10, iss 9
PLoS ONE
PLoS ONE, Vol 10, Iss 9, p e0137104 (2015)
Malone, CD; Olson, ES; Mattrey, RF; Jiang, T; Tsien, RY; & Nguyen, QT. (2015). Tumor detection at 3 tesla with an activatable cell penetrating peptide dendrimer (ACPPD-Gd), a T1 magnetic resonance (MR) molecular imaging agent. PLoS ONE, 10(9). doi: 10.1371/journal.pone.0137104. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/8171h3wq

Author(s): Malone, Christopher D; Olson, Emilia S; Mattrey, Robert F; Jiang, Tao; Tsien, Roger Y; Nguyen, Quyen T | Abstract: PurposeThe ability to detect small malignant lesions with magnetic resonance imaging (MRI) is limited by inadequate accumula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39eaad0eac861a6d1659269d28bf7bd3
https://escholarship.org/uc/item/8171h3wq

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Early detection of thrombin activity in neuroinflammatory disease

Autor: Beth Friedman, Jay L. Degen, Roger Y. Tsien, Michael A. Whitney, Dimitri S. Smirnoff, Eric S. Mullins, Dimitrios Davalos, Mark A. Petersen, Emilia S. Olson, Kim M. Baeten, Katerina Akassoglou, Catherine Bedard, Jae K. Ryu

Publikováno v: Davalos, D; Baeten, KM; Whitney, MA; Mullins, ES; Friedman, B; Olson, ES; et al.(2014). Early detection of thrombin activity in neuroinflammatory disease. Annals of Neurology, 75(2), 303-308. doi: 10.1002/ana.24078. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/6g15x2r0
Annals of Neurology
Annals of neurology, vol 75, iss 2

Although multiple sclerosis (MS) has been associated with the coagulation system, the temporal and spatial regulation of coagulation activity in neuroinflammatory lesions is unknown. Using a novel molecular probe, we characterized the activity patter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffd2df55b85a717e14989286aa8f19a8
http://www.escholarship.org/uc/item/6g15x2r0

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Toward in vivo detection of hydrogen peroxide with ultrasound molecular imaging

Autor: Emilia S. Olson, Boemha Yi, Joseph Wang, Robert F. Mattrey, Wei Gao, Christopher D. Malone, Jahir Orozco, Zhe Wu, Mohammad Eghtedari

Publikováno v: Biomaterials. 34(35)

We present a new class of ultrasound molecular imaging agents that extend upon the design of micromotors that are designed to move through fluids by catalyzing hydrogen peroxide (H_2O_2) and propelling forward by escaping oxygen microbubbles. Micromo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::924e4b1625a8168c95ecfa93d25dc86a
https://pubmed.ncbi.nlm.nih.gov/23958028

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