Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Emilia R. Dellacecca"'
Autor:
Ancy Thomas, Saurav Sumughan, Emilia R. Dellacecca, Rohan S. Shivde, Nicola Lancki, Zhussipbek Mukhatayev, Cristina C. Vaca, Fei Han, Levi Barse, Steven W. Henning, Jesus Zamora-Pineda, Suhail Akhtar, Nikhilesh Gupta, Jasmine O. Zahid, Stephanie R. Zack, Prathyaya Ramesh, Dinesh Jaishankar, Agnes S.Y. Lo, Joel Moss, Maria M. Picken, Thomas N. Darling, Denise M. Scholtens, Daniel F. Dilling, Richard P. Junghans, I. Caroline Le Poole
Publikováno v:
JCI Insight, Vol 6, Iss 22 (2021)
Mutations underlying disease in tuberous sclerosis complex (TSC) give rise to tumors with biallelic mutations in TSC1 or TSC2 and hyperactive mammalian target of rapamycin complex 1 (mTORC1). Benign tumors might exhibit de novo expression of immunoge
Externí odkaz:
https://doaj.org/article/f0d788c1bbd34b7ead95bd619eb9df37
Autor:
Zhussipbek Mukhatayev, Emilia R. Dellacecca, Cormac Cosgrove, Rohan Shivde, Dinesh Jaishankar, Katherine Pontarolo-Maag, Jonathan M. Eby, Steven W. Henning, Yekaterina O. Ostapchuk, Kettil Cedercreutz, Alpamys Issanov, Shikhar Mehrotra, Andreas Overbeck, Richard P. Junghans, Joseph R. Leventhal, I. Caroline Le Poole
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Vitiligo is an autoimmune skin disease characterized by melanocyte destruction. Regulatory T cells (Tregs) are greatly reduced in vitiligo skin, and replenishing peripheral skin Tregs can provide protection against depigmentation. Ganglioside D3 (GD3
Externí odkaz:
https://doaj.org/article/2aa1452d89f0471bb166b8aac11bb57f
Autor:
Cormac Cosgrove, Emilia R. Dellacecca, Michael I. Nishimura, I. Caroline Le Poole, Hans E. N. Bergmans
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1 (2019)
Tumor immunotherapy using gene-modified T cells has already met with considerable success in the treatment of metastatic melanoma and B cell lymphoma. With improving patient prognoses, new questions arise. In particular, the long-term consequences of
Externí odkaz:
https://doaj.org/article/145c95d215cc4b3fb69f8db492a7a925
Publikováno v:
International Journal of Hematology. 117:634-639
Autor:
Joanina K. Gicobi, Zhiming Mao, Grace DeFranco, Ying Li, Xin Liu, Jacob B. Hirdler, Vianca V. Vianzon, Emilia R. Dellacecca, Michelle A. Hsu, Whitney Barham, Yohan Kim, Feven Abraha, William S. Harmsen, Yiyi Yan, Roxana S. Dronca, Mojun Zhu, Svetomir N. Markovic, Aaron S. Mansfield, Yi Lin, Xiaosheng Wu, Dawn Owen, Michael P. Grams, Jacob J. Orme, Fabrice Lucien, Hu Zeng, Sean S. Park, Haidong Dong
Cytotoxic T lymphocytes (CTL) are indispensable in anti-tumor immunity. Although CTLs are prone to exhaustion in patients with advanced cancer, T cell resiliency explains the presence of tumor-reactive CTLs that are less exhausted, capable of cytolyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbaa495000157ab4f823a72e622cdc3a
https://doi.org/10.1101/2022.11.25.517988
https://doi.org/10.1101/2022.11.25.517988
Autor:
Fei Han, Christian M. Ankney, Daniel F. Dilling, Levi Barse, Alexander Yemelyanov, Steven W. Henning, I. Caroline Le Poole, Emilia R. Dellacecca, Dinesh Jaishankar, Vera P. Krymskaya, Cormac Cosgrove
Publikováno v:
Am J Respir Cell Mol Biol
Patients with lymphangioleiomyomatosis (LAM) develop pulmonary cysts associated with neoplastic, smooth muscle–like cells that feature neuroendocrine cell markers. The disease preferentially affects premenopausal women. Existing therapeutics do not
Autor:
Emilia R. Dellacecca, Zhussipbek Mukhatayev, Suhail Akhtar, Levi Barse, Jesus Zamora-Pineda, Dinesh Jaishankar, Fei Han, Nikhilesh Gupta, Ancy Thomas, Thomas N. Darling, Daniel F. Dilling, Steven W. Henning, Saurav Sumughan, Agnes Lo, Cristina C. Vaca, Prathyaya Ramesh, I. Caroline Le Poole, Richard P. Junghans, Maria M. Picken, Joel Moss, Stephanie R. Zack, Denise M. Scholtens, Jasmine O. Zahid, Nicola Lancki, Rohan Shivde
Publikováno v:
JCI Insight
Mutations underlying disease in tuberous sclerosis complex (TSC) give rise to tumors with biallelic mutations in TSC1 or TSC2 and hyperactive mammalian target of rapamycin complex 1 (mTORC1). Benign tumors might exhibit de novo expression of immunoge
Autor:
Dinesh, Jaishankar, Cormac, Cosgrove, Prathyaya, Ramesh, James, Mahon, Rohan, Shivde, Emilia R, Dellacecca, Shiayin F, Yang, Jeffrey, Mosenson, José A, Guevara-Patiño, I Caroline, Le Poole
Publikováno v:
Cell Stress Chaperones
Developing immunosuppressive therapies for autoimmune diseases comes with a caveat that immunosuppression may promote the risk of developing other conditions or diseases. We have previously shown that biolistic delivery of an expression construct enc
Autor:
Levi Barse, Nicola Lancki, Steven W. Henning, Dinesh Jaishankar, Herbert L. Mathews, I. Caroline Le Poole, Ron Price, Kirsten Webb, Emilia R. Dellacecca, Linda Witek Janusek
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227909 (2020)
PLoS ONE
PLoS ONE
Vitiligo is a T-cell mediated skin disorder characterized by progressive loss of skin color. In individuals genetically predisposed to the disease, various triggers contribute to the initiation of vitiligo. Precipitating factors can stress the skin,
Autor:
Emilia R. Dellacecca, Rohan Shivde, I. C. Le Poole, Roopal V. Kundu, Stephanie M. Rangel, Cormac Cosgrove, Julia M. Mhlaba
Publikováno v:
Journal of Investigative Dermatology. 141:S41