Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Emilia M. Ortiz"'
Autor:
Gustavo V. Mallo, Andrés Garcia-Montero, Juan L. Iovanna, Emilia M. Ortiz, Fritz Fiedler, Sophie Vasseur, Eduardo T. Cánepa, Silvia N.J. Moreno
Publikováno v:
Biochemical Journal. 343:377-383
Rat p8 mRNA was discovered because of its strong activation in pancreas during the acute phase of pancreatitis. We report here structural and functional data on the mouse p8 gene. The mouse p8 polypeptide is 80 amino acids long and shows 91% and 75%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e16e828310118edbc7f98068a14afa2
https://doi.org/10.1042/bj3430377
https://doi.org/10.1042/bj3430377
Autor:
Jean Charles Dagorn, Juan L. Iovanna, Hans Bödeker, David Malka, Emilia M. Ortiz, Sophie Vasseur, Nelson Dusetti
Publikováno v:
Gastroenterology. 114:808-816
Background & Aims: Free radicals are involved in the pathogenesis of acute pancreatitis, during which pancreatitis-associated protein (PAP)-I is overexpressed. We explored whether PAP-I expression could be induced by oxidative stress and whether it c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f87e58ed148d71edcaad3aa7fd8457f5
https://doi.org/10.1016/s0016-5085(98)70595-5
https://doi.org/10.1016/s0016-5085(98)70595-5
Autor:
Juan L. Iovanna, Oscar R. Burrone, Nelson Dusetti, Jean-Charles Dagorn, Horacio Romeo, Sophie Vasseur, Emilia M. Ortiz
Publikováno v:
Journal of Biological Chemistry. 272:5800-5804
The pancreatitis-associated protein I (PAP I) is a pancreatic secretory protein expressed in pancreas during acute pancreatitis but not in the healthy pancreas. The promoter of the PAP I gene thus represents a potential candidate to drive expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006af8e608a5b1ccf52ca8ef128884f0
https://doi.org/10.1074/jbc.272.9.5800
https://doi.org/10.1074/jbc.272.9.5800
Autor:
V. Keim, Juan L. Iovanna, Jean-Charles Dagorn, Nelson Dusetti, Emilia M. Ortiz, Gustavo V. Mallo
Publikováno v:
Archives of Biochemistry and Biophysics. 330:129-132
During the acute phase of pancreatitis, expression of most pancreatic enzymes decreases, whereas mRNAs of pancreatitis associated protein and lithostathine/reg increase dramatically. In the present study we have investigated the effect of serum from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2968e4048f0c40f49fa3f652beaca60
https://doi.org/10.1006/abbi.1996.0234
https://doi.org/10.1006/abbi.1996.0234
Publikováno v:
Journal of Biological Chemistry. 270:22417-22421
Expression of the pancreatitis-associated protein I (PAP I), an exocrine pancreatic protein, increases rapidly and strongly in acinar cells during the acute phase of pancreatitis. This is reminiscent of the response to stress of acute phase proteins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bd53c7ca7a26c889e0026f3f7f9441f
https://doi.org/10.1074/jbc.270.38.22417
https://doi.org/10.1074/jbc.270.38.22417
Autor:
Nelson Dusetti, Emilia M. Ortiz, Juan L. Iovanna, David Malka, Hans Bödeker, Sophie Vasseur, Jean Charles Dagorn, Patrick Verrando
Publikováno v:
Gastroenterology. 119(3)
Background & Aims: Tumor necrosis factor (TNF)-α contributes to the development of acute pancreatitis. Because TNF-α is involved in the control of apoptosis, we studied its interaction with the pancreatic apoptotic pathway. Methods: Pancreatic acin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbfbc6f5ba895defb075d5dc6a8516fb
https://pubmed.ncbi.nlm.nih.gov/10982776
https://pubmed.ncbi.nlm.nih.gov/10982776
Autor:
Volker Keim, Emilia M. Ortiz, Ezequiel Calvo, Fritz Fiedler, Jean Morisset, Gustavo V. Mallo, Sophie Vasseur, Juan L. Iovanna
Publikováno v:
The Journal of biological chemistry. 272(51)
To characterize at the molecular level the pancreatic emergency program set up by the pancreatic cells in response to pancreatitis, we have developed a strategy in which the phenotype of the pancreatitis affected pancreas is established by characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6719264baa13fbf2fd4013fb3471017c
https://pubmed.ncbi.nlm.nih.gov/9405444
https://pubmed.ncbi.nlm.nih.gov/9405444
Publikováno v:
Archives of biochemistry and biophysics. 340(1)
Previous analysis of the rat PAP I promoter indicated that the region between nt −180 and −81 possessed silencer activity in cells that did not express PAP I. Based on this finding, we performed a series of experiments to characterize functionall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebcc0c72ec46f583f94ad1ca13cbf24
https://pubmed.ncbi.nlm.nih.gov/9126283
https://pubmed.ncbi.nlm.nih.gov/9126283
Autor:
L Masciotra, Giuseppe Montalto, Jean Charles Dagorn, Nelson Dusetti, Emilia M. Ortiz, J. L. Iovanna
Publikováno v:
British Journal of Cancer
Pancreatitis-associated protein I (PAP I) is a secretory protein first described as an acute phase reactant during acute pancreatitis. Recently, induction of the PAP I gene was also described in liver during hepatocarcinogenesis. To investigate the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a8800b0e014b78d40063461e1576188
https://pubmed.ncbi.nlm.nih.gov/8956791
https://pubmed.ncbi.nlm.nih.gov/8956791
Publikováno v:
The Biochemical journal. 311
We have previously characterized the rat pancreatitis-associated protein I (PAP I) gene by nucleotide sequencing. We describe in this paper its promoter region by analysing the regulatory functions associated with the DNA sequence comprising nt -1253
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deed155586157a54b86ba331e7a01f1f
https://pubmed.ncbi.nlm.nih.gov/7487908
https://pubmed.ncbi.nlm.nih.gov/7487908