Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Emilia Krypotou"'
Autor:
Emilia Krypotou, Mariela Scortti, Christin Grundström, Melanie Oelker, Ben F. Luisi, A. Elisabeth Sauer-Eriksson, José Vázquez-Boland
Publikováno v:
Cell Reports, Vol 26, Iss 7, Pp 1815-1827.e5 (2019)
Summary: To optimize fitness, pathogens selectively activate their virulence program upon host entry. Here, we report that the facultative intracellular bacterium Listeria monocytogenes exploits exogenous oligopeptides, a ubiquitous organic N source,
Externí odkaz:
https://doaj.org/article/dc2d68857c334db6b00d754374d93fac
Publikováno v:
mBio, Vol 8, Iss 3 (2017)
ABSTRACT The Gram-positive facultative intracellular bacterium Listeria monocytogenes is the causative agent of listeriosis, a severe food-borne infection. Pregnant women are at risk of contracting listeriosis, which can potentially lead to miscarria
Externí odkaz:
https://doaj.org/article/41e6f76d894c41a59177396f7ff16dfe
Autor:
Emilia Krypotou, George Diallinas
Publikováno v:
Bio-Protocol, Vol 3, Iss 22 (2013)
Transport assays allow the direct kinetic analysis of a specific transporter by measuring apparent Km and Vmax values, and permit the characterization of substrate specificity profiles through competition assays. In this protocol, we describe a rapid
Externí odkaz:
https://doaj.org/article/3292efc649014293915c4be9608dfdc8
Autor:
Emilia Krypotou, Guy E. Townsend, Xiaohui Gao, Shoichi Tachiyama, Jun Liu, Nick D. Pokorzynski, Andrew L. Goodman, Eduardo A. Groisman
Publikováno v:
Science
Therapeutic manipulation of the gut microbiota holds great potential for human health. The mechanisms bacteria use to colonize the gut therefore present valuable targets for clinical intervention. We now report that bacteria use phase separation to e
Autor:
George Diallinas, George Lambrinidis, Panagiotis Marakos, Emilia Krypotou, Efthymios-Spyridon Gavriil, Markelos Kairis, Dimitra Benaki, Georgia Sioupouli, Emmanuel Mikros, Nicole Pouli, Nikolaos Lougiakis
Publikováno v:
Bioorganic & Medicinal Chemistry. 24:5941-5952
In the course of our study on fungal purine transporters, a number of new 3-deazapurine analogues have been rationally designed, based on the interaction of purine substrates with the Aspergillus nidulans FcyB carrier, and synthesized following an ef
Autor:
Emmanuel Mikros, Jacob Bobonis, Emilia Krypotou, Alexandros A. Pittis, Claudio Scazzocchio, George Diallinas, Toni Gabaldón, Thomas Evangelidis
Publikováno v:
Molecular Microbiology. 96:927-950
NCS1 proteins are H(+)/Na(+) symporters specific for the uptake of purines, pyrimidines and related metabolites. In this article, we study the origin, diversification and substrate specificity of fungal NCS1 transporters. We show that the two fungal
Publikováno v:
Fungal Genetics and Biology
Fungal Genetics and Biology, Elsevier, 2015, 75, pp.56-63. ⟨10.1016/j.fgb.2015.01.009⟩
Fungal Genetics and Biology, Elsevier, 2015, 75, pp.56-63. ⟨10.1016/j.fgb.2015.01.009⟩
International audience; The Nucleobase-Ascorbate Transporter (NAT) family includes members in nearly all domains of life. Functionally characterized NAT transporters from bacteria, fungi, plants and mammals are ion-coupled symporters specific for the
Publikováno v:
mBio, Vol 8, Iss 3, p e00949-17 (2017)
Vazquez-Boland, J, Krypotou, E & Scortti, M 2017, ' Listeria placental infection ', mBio . https://doi.org/10.1128/mBio.00949-17
mBio, Vol 8, Iss 3 (2017)
Vazquez-Boland, J, Krypotou, E & Scortti, M 2017, ' Listeria placental infection ', mBio . https://doi.org/10.1128/mBio.00949-17
mBio, Vol 8, Iss 3 (2017)
The Gram-positive facultative intracellular bacterium Listeria monocytogenes is the causative agent of listeriosis, a severe food-borne infection. Pregnant women are at risk of contracting listeriosis, which can potentially lead to miscarriage, still
Publikováno v:
Molecular Microbiology. 93:129-145
The AzgA purine/H(+) symporter of Aspergillus nidulans is the founding member of a functionally and phylogenetically distinct transporter family present in fungi, bacteria and plants. Here a valid AzgA topological model is built based on the crystal
Autor:
Emmanuel Mikros, Vassilios Myrianthopoulos, George Diallinas, Sotiris Amillis, Emilia Krypotou, Vasiliki Kosti
Publikováno v:
Journal of Biological Chemistry. 287:36792-36803
The recent elucidation of crystal structures of a bacterial member of the NCS1 family, the Mhp1 benzyl-hydantoin permease from Microbacterium liquefaciens, allowed us to construct and validate a three-dimensional model of the Aspergillus nidulans pur