Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Emilia Castigli"'
Autor:
Maria Di Bari, Vanessa Tombolillo, Francesco Alessandrini, Claudia Guerriero, Mario Fiore, Italia Anna Asteriti, Emilia Castigli, Miriam Sciaccaluga, Giulia Guarguaglini, Francesca Degrassi, Ada Maria Tata
Publikováno v:
Cells, Vol 10, Iss 7, p 1727 (2021)
Background: Glioblastoma multiforme (GBM) is characterized by several genetic abnormalities, leading to cell cycle deregulation and abnormal mitosis caused by a defective checkpoint. We previously demonstrated that arecaidine propargyl ester (APE), a
Externí odkaz:
https://doaj.org/article/4efaad0827cb4138b8b9aaf9c2272d2e
Autor:
Miriam Sciaccaluga, Giuseppina D'Alessandro, Francesca Pagani, Giuseppina Ferrara, Nadia Lopez, Tracy Warr, Paolo Gorello, Alessandra Porzia, Fabrizio Mainiero, Antonio Santoro, Vincenzo Esposito, Giampaolo Cantore, Emilia Castigli, Cristina Limatola
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73426 (2013)
Glioblastoma (GBM) is the most common and aggressive form of brain tumor, characterized by high migratory behavior and infiltration in brain parenchyma which render classic therapeutic approach ineffective. The migratory behaviour of GBM cells could
Externí odkaz:
https://doaj.org/article/c20e6b5ac06749638ebb30238b859900
Autor:
Federica Susta, Lanfranco Corazzi, Luciano Binaglia, Maya Petricciuolo, Rita Roberti, Davide Chiasserini, Lara Macchioni, Emilia Castigli, Magdalena Davidescu, Pier Luigi Orvietani
Publikováno v:
Journal of Proteomics. 152:329-338
Glioblastoma (GBM) is the most common and aggressive brain tumour of adults. The metabolic phenotype of GBM cells is highly dependent on glycolysis; therefore, therapeutic strategies aimed at interfering with glycolytic pathways are under considerati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a332ff4b57cf75a0be2688746a075d
https://doi.org/10.1016/j.jprot.2016.11.013
https://doi.org/10.1016/j.jprot.2016.11.013
Autor:
Davide Ragozzino, Francesca Pagani, Miriam Sciaccaluga, Cristina Limatola, Antonio Santoro, Cristina Bertollini, Giuseppina D'Alessandro, Bernard Fioretti, Giampaolo Cantore, Emilia Castigli, Myriam Catalano, Fabio Franciolini, Maria Rosito, Luigi Catacuzzeno
Publikováno v:
American Journal of Physiology-Cell Physiology. 299:C175-C184
The activation of ion channels is crucial during cell movement, including glioblastoma cell invasion in the brain parenchyma. In this context, we describe for the first time the contribution of intermediate conductance Ca2+-activated K (IKCa) channel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f999ef5f549fff061e10c70e9dd94c
https://doi.org/10.1152/ajpcell.00344.2009
https://doi.org/10.1152/ajpcell.00344.2009
Autor:
Angela Corcelli, Lara Macchioni, Rita Vitale, Rita Roberti, Graziella Migliorati, Emilia Castigli, Gaetano Scaramozzino, Magdalena Davidescu, Lanfranco Corazzi, Maria Cristina Marchetti
Publikováno v:
Scientific Reports
The energy metabolism of tumor cells relies on aerobic glycolysis rather than mitochondrial oxidation. This difference between normal and cancer cells provides a biochemical basis for new therapeutic strategies aimed to block the energy power plants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c4a7697521e7fc7869b6cdcfb6522e
http://hdl.handle.net/11391/1354711
http://hdl.handle.net/11391/1354711
Autor:
Maria Rita Micheli, Miriam Sciaccaluga, Alexander A. Harper, Bernard Fioretti, Rodolfo Bova, Emilia Castigli, Fabio Franciolini, Luigi Catacuzzeno
Publikováno v:
Cellular Physiology and Biochemistry. 18:47-56
We report here the expression and properties of the intermediate-conductance Ca2+-activated K+ (IKCa) channel in the GL-15 human glioblastoma cell line. Macroscopic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::284fb3f53c8226cffc35eea42301f2f2
https://doi.org/10.1159/000095135
https://doi.org/10.1159/000095135
Publikováno v:
Molecular Biology Reports. 28:47-52
The binding of citrate and acidic peptide DDSDEEN with DNA in the presence of divalent cations is compared. Citric acid shows a higher number of binding sites on the DNA compared to the peptide; this is probably due to the bigger sitric hindrance of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fe828eef970ef60bb8f4ff0059477e0
https://doi.org/10.1023/a:1011955013990
https://doi.org/10.1023/a:1011955013990
Autor:
Miriam Sciaccaluga, Luigi Sforna, Antonio Michelucci, Emilia Castigli, Bernard Fioretti, Fabio Franciolini, Luigi Catacuzzeno, Francesco Aiello
Publikováno v:
The Journal of membrane biology. 247(1)
The swelling-activated chloride current (I Cl,Vol) is abundantly expressed in glioblastoma (GBM) cells, where it controls cell volume and invasive migration. The transduction pathway mediating I Cl,Vol activation in GBM cells is, however, poorly unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d47b1596d0f6ff3eca0013eb9ea6340b
https://pubmed.ncbi.nlm.nih.gov/24240542
https://pubmed.ncbi.nlm.nih.gov/24240542
Autor:
Cinzia Fabbiano, Emilia Castigli, Antonino Raco, Claudia Conte, Miriam Sciaccaluga, Maria Di Bari, Michela Ferretti, Paola Ruggieri, Donatella Ponti, Antonella Calogero, Ruggero Ricordy, Ada Maria Tata
Publikováno v:
Journal of Cellular and Molecular Medicine
Muscarinic receptors, expressed in several primary and metastatic tumours, appear to be implicated in their growth and propagation. In this work we have demonstrated that M2 muscarinic receptors are expressed in glioblastoma human specimens and in gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::447565d019c0d48dd8be403acb1dcc31
https://pubmed.ncbi.nlm.nih.gov/23490231
https://pubmed.ncbi.nlm.nih.gov/23490231
Autor:
Antonella Calogero, Luigi Sforna, Luigi Catacuzzeno, Fabio Franciolini, Emilia Castigli, Francesco Aiello, Bernard Fioretti, Ada Maria Tata, Paola Ruggieri
Glioblastoma cells in vivo are exposed to a variety of promigratory signals, including undefined serum components that infiltrate into high grade gliomas as result of blood–brain barrier breakdown. Glioblastoma cell migration has been further shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e4a41fa10f7c2ecd2b4754ddfc4904
http://hdl.handle.net/11573/43554
http://hdl.handle.net/11573/43554