Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Emilia A H Vanni"'
Autor:
Emilia A H Vanni, Joseph W Foley, Andrew J Davison, Marvin Sommer, Dongmei Liu, Phillip Sung, Jennifer Moffat, Leigh Zerboni, Ann M Arvin
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009166 (2020)
Herpes simplex virus 1 (HSV-1) infects skin and mucosal epithelial cells and then travels along axons to establish latency in the neurones of sensory ganglia. Although viral gene expression is restricted during latency, the latency-associated transcr
Externí odkaz:
https://doaj.org/article/4837bd804ca54bc4b614cfe9b39aa1fc
Autor:
Fujun Hou, Dongli Pan, Jean M. Pesola, George M. Church, Xuewei Yang, Jenna Morris-Love, Priya Raja, David M. Knipe, Qiongyan Wang, Hyung Suk Oh, Emilia A. H. Vanni, Boqiang Sun, Xiaofeng Yu, Seamus McCarron, Donald M. Coen, Alex Hay-Man Ng
Publikováno v:
Nat Microbiol
MicroRNA miR-138, which is highly expressed in neurons, represses herpes simplex virus 1 (HSV-1) lytic cycle genes by targeting viral ICP0 messenger RNA, thereby promoting viral latency in mice. We found that overexpressed miR-138 also represses lyti
Autor:
Phillip Sung, Ann M. Arvin, Leigh Zerboni, Dongmei Liu, Andrew J. Davison, Emilia A. H. Vanni, Jennifer F. Moffat, Marvin Sommer, Joseph W. Foley
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009166 (2020)
PLoS Pathogens
PLoS Pathogens
Herpes simplex virus 1 (HSV-1) infects skin and mucosal epithelial cells and then travels along axons to establish latency in the neurones of sensory ganglia. Although viral gene expression is restricted during latency, the latency-associated transcr
Autor:
Emilia A. H. Vanni, Donna M. Neumann, Pankaj Singh, Sanae Nakayama, David C. Bloom, Enrico R. Barrozo, Ann M. Arvin
Publikováno v:
J Virol
During all stages of infection, herpes simplex virus 1 (HSV-1) expresses viral microRNAs (miRNAs). There are at least 20 confirmed HSV-1 miRNAs, yet the roles of individual miRNAs in the context of viral infection remain largely uncharacterized. We c
Autor:
Suzanne E. Hickman, Emilia A. H. Vanni, Jay A. Fishman, Rosio Fernandez, Erik R. Abels, Joseph El Khoury, Yiming Yang, Han Chen, Miguel Velazquez-Palafox, Ian J. Taylor, Terry K. Means, Donald M. Coen, Mary E. Piper, Fei Ji, Eric S. Rosenberg, Rebekah J. Lane, Ruslan I. Sadreyev, Jean M. Pesola, Pritha Sen, Bo Li, Adrian R. Wilkie, Liza M. Morsett
Publikováno v:
Science Advances
CMV-infected monocytes are unable to phagocytose fungal pathogens yet produce inflammation associated with rejection and GVHD.
Cytomegalovirus (CMV) is an important cause of morbidity and mortality in the immunocompromised host. In transplant re
Cytomegalovirus (CMV) is an important cause of morbidity and mortality in the immunocompromised host. In transplant re
Publikováno v:
Journal of Virology. 86:11209-11222
Herpes simplex virus 1 (HSV-1) immediate-early protein ICP0 localizes to cellular structures known as promyelocytic leukemia protein (PML) nuclear bodies or ND10 and disrupts their integrity by inducing the degradation of PML. There are six PML isofo
Publikováno v:
Journal of virology. 86(11)
The viral ubiquitin ligase ICP0 is required for efficient initiation of herpes simplex virus 1 (HSV-1) lytic infection and productive reactivation of viral genomes from latency. ICP0 has been shown to target a number of specific cellular proteins for