Zobrazeno 1 - 10 of 19 pro vyhledávání: '"Emili González-Pérez"'
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Akademický článek
Interspecies Brain PBPK Modeling Platform to Predict Passive Transport through the Blood–Brain Barrier and Assess Target Site Disposition
Autor: Parsshava Mehta, Amira Soliman, Leyanis Rodriguez-Vera, Stephan Schmidt, Paula Muniz, Monica Rodriguez, Marta Forcadell, Emili Gonzalez-Perez, Valvanera Vozmediano
Publikováno v: Pharmaceutics, Vol 16, Iss 2, p 226 (2024)
The high failure rate of central nervous system (CNS) drugs is partly associated with an insufficient understanding of target site exposure. Blood–brain barrier (BBB) permeability evaluation tools are needed to explore drugs’ ability to access th
Externí odkaz: https://doaj.org/article/6ba5656c4fd543da849006b559600dd4
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Population relationships in the Mediterranean revealed by autosomal genetic data (AluandAlu/STR compound systems)
Autor: Mostafa Kandil, Magdalena Gayà-Vidal, Esther Esteban, Jean-Michel Dugoujon, Pedro Moral, F. Luna, María Soledad Mesa, Angela Saetta, Vicente Fuster, Marc Via, Georgios Athanasiadis, Emili González-Pérez, Nisrine Bissar-Tadmouri, Nourdin Harich
Publikováno v: American Journal of Physical Anthropology. 141:430-439
The variation of 18 Alu polymorphisms and 3 linked STRs was determined in 1,831 individuals from 15 Mediterranean populations to analyze the rela- tionships between human groups in this geographical region and provide a complementary perspective to i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bbb82552cc53f6e18a1d3b163cb0609b
https://doi.org/10.1002/ajpa.21161
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Genetic Change in the Polynesian Population of Easter Island: Evidence from Alu Insertion Polymorphisms
Autor: Clara García-Moro, Esther Esteban, Marc Via, Pedro Moral, Emili González-Pérez, Miguel Hernández
Publikováno v: Annals of Human Genetics. 70:829-840
Summary The origin of Pacific islanders is still an open issue in human population genetics. To address this topic we analyzed a set of 18 Alu insertion polymorphisms in a total of 176 chromosomes from native Easter Island inhabitants (Rapanui). Avai
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508604dcc5c1143d2eeda7506b4eaf97
https://doi.org/10.1111/j.1469-1809.2006.00293.x
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Alu polymorphisms in Jerba Island population (Tunisia): Comparative study in Arab and Berber groups
Autor: Nicole Maca-Meyer, Pedro Moral, Hussein Khodjet El Khil, Besma Yacoubi-Loueslati, Amel Benammar Elgaaied, Hajer Ennafaa, Mohamed Ben Amor, Emili González-Pérez
Publikováno v: Annals of Human Biology. 33:634-640
Jerba Island represents an interesting area because four distinct ethnic groups have been cohabiting there until now: Arabs, Berbers, dark-skinned people of sub-Saharan origin and Jews. Religious and cultural differences seem to have constituted an o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58820130066fa05914c4fc09c41b8a77
https://doi.org/10.1080/03014460600931087
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Angiotensin I converting enzyme polymorphism effects in patients with normal pressure hydrocephalus syndrome before and after surgery
Autor: Cristina Solé-Padullés, Maria A. Poca, Carme Junqué, Maite Barrios, Maria Mataró, Emili González-Pérez, Juan Sahuquillo, Maria del Mar Matarín, Imma C. Clemente, Pedro Moral, David Bartrés-Faz
Publikováno v: ResearcherID
Previous reports have suggested an association between the insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE), cardiovascular disease, and cognitive performance. Normal pressure hydrocephalus (NPH) is considered to be an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10ddbc5b008969c0bc3896391580fdee
https://doi.org/10.1007/s00415-005-0630-5
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Genetic relationships among Berbers and South Spaniards based on CD4 microsatellite/Alu haplotypes
Autor: A. López-Alomar, Esther Esteban, Nourdin Harich, Pedro Moral, F. Luna, Marc Via, Emili González-Pérez
Publikováno v: Annals of Human Biology. 31:202-212
CD4 STR/Alu haplotype diversity, both for its qualitative and quantitative properties, has been widely used in molecular anthropology to clarify the degree of genetic relationships among human populations.CD4 STR/Alu variation was studied in two West
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9680327c780fad2c410bfdd423d9f83d
https://doi.org/10.1080/03014460310001652275
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Poorer cognitive performance in humans with mild cognitive impairment carrying the T variant of the Glu/Asp NOS3 polymorphism
Autor: Cristina Solé-Padullés, David Bartrés-Faz, Emili González-Pérez, Carme Junqué, Marc Via, Immaculada C. Clemente, Pedro Moral, Mar Matarín, Antoni Moya
Publikováno v: Neuroscience Letters. 358:5-8
Mild cognitive impairment (MCI) is a transitional state between normal aging and Alzheimer's disease (AD) and is a high-risk condition for dementia. The endothelial nitric oxide synthase (NOS3) gene encodes endothelial NOS, an enzyme that regulates t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e25b62e8b1ba9e08b73874391cddac
https://doi.org/10.1016/j.neulet.2003.12.044
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Patterns of phenotypic covariation and correlation in modern humans as viewed from morphological integration
Autor: Rolando González-José, Miquel Hernández, Silvina Van Der Molen, Emili González-Pérez
Publikováno v: American Journal of Physical Anthropology. 123:69-77
Proportionality of phenotypic and genetic distance is of crucial importance to adequately focus on population history and structure, and it depends on the proportionality of genetic and phenotypic covariance. Constancy of phenotypic covariances is un
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aa54a650ac1fa047c06161cd99e48b6c
https://doi.org/10.1002/ajpa.10302
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9
Lack of association between methylenetetrahydrofolate reductase (MTHFR) C677T and ischaemic heart disease (IHD): family-based association study in a Spanish population
Autor: M. Bao, Pedro Moral, Esther Esteban, N. Valveny, Emili González-Pérez, A. López-Alomar, Marc Via, Enric Domingo
Publikováno v: Clinical Genetics. 62:235-239
The effect of the C677T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene, traditionally associated with ischaemic heart disease (IHD), was assessed in a Spanish population. The transmission disequilibrium test (TDT) was used to de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::588b0fe6b47de35cb7b3697dc905b2bf
https://doi.org/10.1034/j.1399-0004.2002.620309.x
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Biweekly cetuximab in combination with FOLFOX-4 in the first-line treatment of wild-type KRAS metastatic colorectal cancer: final results of a phase II, open-label, clinical trial (OPTIMIX-ACROSS Study)
Autor: Julen, Fernandez-Plana, Carlos, Pericay, Guillermo, Quintero, Vicente, Alonso, Antonieta, Salud, Miguel, Mendez, Mercedes, Salgado, Eugeni, Saigi, Luis, Cirera, Emili, González-Pérez
Publikováno v: Repositorio Abierto de la UdL
Universitad de Lleida
BMC Cancer
Recercat. Dipósit de la Recerca de Catalunya
instname
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Background: This phase II study aims to evaluate the efficacy and safety of biweekly cetuximab in combination with oxaliplatin, leucovorin, and fluorouracil (FOLFOX-4) as first-line treatment of metastatic wild-type KRAS colorectal cancer. Methods: P
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e57ebf4d505fd6891428e29805bc617
https://hdl.handle.net/10459.1/70838
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