Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Emile Velthuisen"'
Autor:
Nima Akhavein, Marc M. Baum, Manjula Gunawardana, John A. Moss, Sandrine Calvez, Mariana Remedios-Chan, Rob Fanter, Steve Lenhard, Samantha Rusk, Leonard Azzarano, Deborah McCoy, Beat Jucker, Brian Johns, Matt Burke, Emile Velthuisen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract GSK2838232 (GSK8232) is a second-generation maturation inhibitor (MI) developed for the treatment of HIV with excellent broad-spectrum virological profiles. The compound has demonstrated promising clinical results as an orally administered a
Externí odkaz:
https://doaj.org/article/a3f234e950404360a54ad36a6723e69e
Autor:
Kushol Gupta, Vesa Turkki, Scott Sherrill-Mix, Young Hwang, Grant Eilers, Louis Taylor, Charlene McDanal, Ping Wang, David Temelkoff, Robert T Nolte, Emile Velthuisen, Jerry Jeffrey, Gregory D Van Duyne, Frederic D Bushman
Publikováno v:
PLoS Biology, Vol 14, Iss 12, p e1002584 (2016)
The allosteric inhibitors of integrase (termed ALLINIs) interfere with HIV replication by binding to the viral-encoded integrase (IN) protein. Surprisingly, ALLINIs interfere not with DNA integration but with viral particle assembly late during HIV r
Externí odkaz:
https://doaj.org/article/2cbb091ccf0f4d93acbf92ec4b7cdc75