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pro vyhledávání: '"Emile S. Pinarbasi"'
Autor:
Emile S. Pinarbasi, Sami J. Barmada
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 6 (2023)
A subset of the neurodegenerative disease frontotemporal lobar degeneration (FTLD) is caused by mutations in the progranulin (GRN) gene. In this issue of the JCI, Marsan and colleagues demonstrate disease-specific transcriptional profiles in multiple
Externí odkaz:
https://doaj.org/article/ca7ad0cd2d6d4310b109c3f4a390ca4d
Active nuclear import and passive nuclear export are the primary determinants of TDP-43 localization
Autor:
Emile S. Pinarbasi, Tolga Cağatay, Ho Yee Joyce Fung, Ying C. Li, Yuh Min Chook, Philip J. Thomas
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Abstract ALS (Amyotrophic Lateral Sclerosis) is a neurodegenerative disease characterized by the redistribution of the RNA binding protein TDP-43 in affected neurons: from predominantly nuclear to aggregated in the cytosol. However, the determinants
Externí odkaz:
https://doaj.org/article/e0bc0cffa6c242cf85832575acd6acd8
Autor:
Emile S. Pinarbasi, Drew Pratt
Publikováno v:
The Cancer Journal. 27:337-343
The classification, diagnosis, and biological understanding of high-grade gliomas has been transformed by an evolving understanding of glioma biology. High-grade gliomas, in particular, have exemplified the impact of molecular alterations in patholog
Autor:
Oleg Kopyov, Noah A. Brown, Elaine A Liu, Praveen Dayalu, Emile S. Pinarbasi, Andrew P. Lieberman, Zhigang Yu
Publikováno v:
Acta Neuropathol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9c0e40208edf8103ea010ac4c48aa7e
https://europepmc.org/articles/PMC8119370/
https://europepmc.org/articles/PMC8119370/
Active nuclear import and passive nuclear export are the primary determinants of TDP-43 localization
Autor:
Ying C. Li, Ho Yee Joyce Fung, Philip Thomas, Emile S. Pinarbasi, Tolga Cagatay, Yuh Min Chook
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Scientific Reports
Scientific Reports
ALS (Amyotrophic Lateral Sclerosis) is a neurodegenerative disease characterized by the redistribution of the RNA binding protein TDP-43 in affected neurons: from predominantly nuclear to aggregated in the cytosol. However, the determinants of TDP-43
Autor:
I-Hui Wu, Philip Thomas, Andrey L. Karamyshev, Emile S. Pinarbasi, Elena B. Tikhonova, Henry Hudson
Publikováno v:
Cell reports
SUMMARY Cells have evolved quality control pathways to prevent the accumulation of improperly localized proteins, which are often toxic. One of these pathways, regulation of aberrant protein production (RAPP), recognizes aberrant secretory proteins d