Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Emile Roberts"'
Autor:
Tomoaki Sobajima, Katarzyna M. Kowalczyk, Stefanos Skylakakis, Daniel Hayward, Luke J. Fulcher, Colette Neary, Caleb Batley, Samvid Kurlekar, Emile Roberts, Ulrike Gruneberg, Francis A. Barr
Publikováno v:
Journal of Cell Biology. 222
Amplification of the mitotic kinase Aurora A or loss of its regulator protein phosphatase 6 (PP6) have emerged as drivers of genome instability. Cells lacking PPP6C, the catalytic subunit of PP6, have amplified Aurora A activity, and as we show here,
Publikováno v:
Daniel Hayward
In eukaryotes, the spindle assembly checkpoint protects genome stability in mitosis by preventing chromosome segregation until incorrect microtubule-kinetochore attachment geometries have been eliminated and chromosome biorientation has been complete
SummaryIn eukaryotes, the spindle assembly checkpoint protects genome stability in mitosis by preventing anaphase onset until incorrect microtubule-kinetochore attachment geometries have been eliminated and chromosome biorientation has been completed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7336520e0f20910e5cd31e56a6fa1a96
https://doi.org/10.1101/2022.05.23.493048
https://doi.org/10.1101/2022.05.23.493048
Autor:
Tomoaki Sobajima, Katarzyna M. Kowalczyk, Stefanos Skylakakis, Daniel Hayward, Luke J. Fulcher, Colette Neary, Caleb Batley, Samvid Kurlekar, Emile Roberts, Ulrike Gruneberg, Francis A. Barr
Amplification of the mitotic kinase Aurora A or loss of its regulator protein phosphatase 6 (PP6) have emerged as drivers of genome instability. Cells lacking PPP6C, the catalytic subunit of PP6, have amplified Aurora A activity and as we show here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6200583c144ec5cb53c2459779e3647
https://doi.org/10.1101/2022.05.23.492953
https://doi.org/10.1101/2022.05.23.492953