Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Emile M. Youssef"'
Autor:
J. Jack Lee, Waun Ki Hong, Khaled A. Hassan, Li Mao, Emile M. Youssef, Reuben Lotan, Kenichi Wakasa, You Hong Fan, Lei Feng, Dafna Lotan, Jean Pierre J. Issa, Scott M. Lippman
Publikováno v:
Clinical Cancer Research. 10:1733-1742
Purpose: Retinoic acid receptor-β2 (RAR-β2) expression is suppressed in oral premalignant lesions and head and neck squamous cell carcinomas (HNSCCs). This study was conducted to determine whether RAR-β2 gene expression in such lesions can be sile
Autor:
Toru Furukawa, Yutaka Hayashi, Akira Horii, Emile M. Youssef, Masato Hoshi, Toshimasa Yatsuoka, Kenzo Kaneko
Publikováno v:
DNA Sequence. 11:541-546
In sporadic human primary pancreatic cancer tissues, loss of heterozygosity is frequently observed in the 1-cM region between D12S81 and D12S1719 at 12q21. Loss of this chromosome arm is known to be associate with a poor prognosis in pancreatic cance
Publikováno v:
Pathology International. 50:549-552
Ovarian hyperstimulation syndrome (OHSS) is the most serious complication of ovulation induction with exogenous gonadotropins, such as human menopausal gonadotropin and follicle-stimulating hormone. These hormones are considered to increase capillary
Autor:
Satoru Mori, Shuji Hayashi, Elsayed I. Salim, Shoji Fukushima, Emile M. Youssef, Hideki Wanibuchi
Publikováno v:
Carcinogenesis. 20:1247-1252
Urinary enzyme levels were investigated in rats administered different promoters in their diet for 32 weeks after being initiated by treatment with 0.05% N-butyl-N-(4-hydroxybutyl)nitrosamine in their drinking water for 4 weeks. All groups were compo
Autor:
Yoshihiro Morishima, Tadayoshi Hasuma, Emile M. Youssef, Masayuki Higashino, Shoji Fukushima, Nobuyasu Takada, Shuzo Otani, Harushi Osugi
Publikováno v:
Japanese Journal of Cancer Research : Gann
Overexpression of cyclin D1 in human esophageal carcinomas has been well documented. The aim of the present study was to assess the expression of cyclin D1 in different types of esophageal epithelial lesions induced by N-nitrosomethylbenzylamine (NMB
Autor:
Harushi Osugi, Yasunori Katsura, Tomoyuki Watanabe, Shoji Fukushima, Nobuyasu Takada, Masayuki Higashino, Tsutomu Matsuda, Emile M. Youssef, Hiroaki Kinoshita, Hideki Wanibuchi
Publikováno v:
Cancer. 76:358-366
Background. A number of studies have indicated that the ki-67 proliferation index is of important prognostic significance for a variety of neoplasias. It was the aim of this study to investigate whether any correlation exits between the MIB-1 prolife
Autor:
Guillermo Garcia-Manero, Taichun Qin, Jaroslav Jelinek, Emile M. Youssef, Jean Pierre J. Issa, Allen S. Yang, Rong Chen
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 13(14)
Purpose: 1-β-d-Arabinofuranosylcytosine (cytarabine; ara-C) is the most active agent in myeloid leukemia. 5-Aza-2′-deoxycytidine (DAC) is a cytosine analogue that inhibits DNA methylation and also has activity in myeloid leukemia. Therefore, we in
Autor:
Emile M. Youssef, Lanlan Shen, C. Marcela Diaz-Montero, Marcos R. Estecio, Alberto J. Montero, Jean Pierre J. Issa, Li Mao
Publikováno v:
Cancer biologytherapy. 5(11)
The epidermal growth factor receptor (EGFR) is a member of the HER/ERB-B family of transmembrane receptor kinases. Overexpression of EGFR confers advantages in cell proliferation, survival, and migration and correlates with decreased survival in mult
Autor:
Reuben Lotan, Yutaka Kondo, Guillermo Garcia-Manero, Eisaku Higuchi, Xu Qi Chen, Jean Pierre J. Issa, Emile M. Youssef
Publikováno v:
Cancer research. 64(7)
A variety of tumor suppressor genes are down-regulated by hypermethylation during carcinogenesis. Using methylated CpG amplification-representation difference analysis, we identified a DNA fragment corresponding to the Tazarotene-induced gene 1 (TIG1
Autor:
Shuho, Semba, Nanami, Itoh, Masafumi, Ito, Emile M, Youssef, Masaru, Harada, Toshiyuki, Moriya, Wataru, Kimura, Mitsunori, Yamakawa
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 8(12)
Premature death associated with colorectal adenocarcinoma occurs in PIK3CG(-/-) mice and overexpression of PIK3CG in colon cancer cells suppresses cell proliferation. We examined expression levels of PIK3CG, a catalytic subunit of phosphatidylinositi