Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Emile J. Clappaert"'
Autor:
Emma Verheye, Daliya Kancheva, Hatice Satilmis, Niels Vandewalle, Rong Fan, Pauline M. R. Bardet, Emile J. Clappaert, Kevin Verstaen, Ann De Becker, Karin Vanderkerken, Kim De Veirman, Damya Laoui
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-22 (2024)
Abstract Background The long-term effectiveness of immunotherapies against Multiple Myeloma (MM) remains elusive, demonstrated by the inevitable relapse in patients. This underscores the urgent need for an in-depth analysis of the MM tumor-immune mic
Externí odkaz:
https://doaj.org/article/8049a040e2134dad946bb92970361e7c
Autor:
Emile J. Clappaert, Daliya Kancheva, Jan Brughmans, Ayla Debraekeleer, Pauline M. R. Bardet, Yvon Elkrim, Dagmar Lacroix, Maida Živalj, Ahmed E.I. Hamouda, Jo A. Van Ginderachter, Sofie Deschoemaeker, Damya Laoui
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Conventional dendritic cells (cDCs) are at the forefront of activating the immune system to mount an anti-tumor immune response. Flt3L is a cytokine required for DC development that can increase DC abundance in the tumor when administered therapeutic
Externí odkaz:
https://doaj.org/article/ad19eef033c8482bbb80dc7e46ef2740
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Therapeutic approaches that engage immune cells to treat cancer are becoming increasingly utilized in the clinics and demonstrated durable clinical benefit in several solid tumor types. Most of the current immunotherapies focus on manipulating T cell
Externí odkaz:
https://doaj.org/article/82be7342eab64ee78d4b721312bc8e43
Autor:
Ana Rita Pombo Antunes, Tony Lahoutte, Ahmet Krasniqi, Emile J. Clappaert, Aleksandar Murgaski, Kiavash Movahedi, Marnik Vuylsteke, Amanda Gonçalves, Geert Stangé, Nick Devoogdt, Jo A. Van Ginderachter, Geert Raes, Matthias D'Huyvetter, Evangelia Bolli, Danielle Berus, Sana M. Arnouk
Publikováno v:
Journal of Controlled Release. 314:1-11
Radioimmunotherapy (RIT) aims to deliver a high radiation dose to cancer cells, while minimizing the exposure of normal cells. Typically, monoclonal antibodies are used to target the radionuclides to cancer cell surface antigens. However, antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1457d1668ae746271e47c55fe72d4720
https://doi.org/10.1016/j.jconrel.2019.10.024
https://doi.org/10.1016/j.jconrel.2019.10.024
Autor:
Xenia Geeraerts, Emile J. Clappaert, Aleksandar Murgaski, Sarah-Maria Fendt, Liesbet Martens, Yvan Saeys, Yvon Elkrim, Dorien Broekaert, Jan Van den Bossche, Kyra E. de Goede, Damya Laoui, Pauline M. R. Bardet, Jo A. Van Ginderachter, Conny Gysemans, Juan Fernández Garcia
Publikováno v:
SSRN Electronic Journal.
Macrophages are often prominently present in the tumor microenvironment, where distinct macrophage populations can differentially affect tumor progression. Although the metabolism of macrophages influences their function, little is known about the me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ea4aa8e7cbbe96f0817ef91a2403fe8
https://doi.org/10.2139/ssrn.3625818
https://doi.org/10.2139/ssrn.3625818
Publikováno v:
Cancers, Vol 11, Iss 5, p 670 (2019)
Cancers
Cancers
Recent advances in cancer immunotherapy have mainly focused on re-activating T-cell responses against cancer cells. However, both priming and activation of effector T-cell responses against cancer-specific antigens require cross-talk with dendritic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea2bd6f23becd4751260e2f61596e5e0
https://www.mdpi.com/2072-6694/11/5/670
https://www.mdpi.com/2072-6694/11/5/670