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Autor:
Charline Alleaume, Jacques Bosq, Alexander Zukiwski, Emile Hutt, Erard M. Gilles, Jacques Bonneterre
Publikováno v:
Cancer Research. 75:P6-08
Background: About 50% of ER positive (ERpos) BCs are resistant to hormone treatment. In absence of ligand, ERs are evenly distributed in nuclei in normal tissue. Upon ligand binding, ERs dimerizes and form a discrete focal subnuclear distribution pat