Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Emil Pai"'
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11215 (2010)
The inhibition of specific SH2 domain mediated protein-protein interactions as an effective chemotherapeutic approach in the treatment of diseases remains a challenge. That different conformations of peptide-ligands are preferred by different SH2 dom
Externí odkaz:
https://doaj.org/article/5e41ac005f934607919e0c513ae22261
Autor:
Scott Franzblau, Ferenc Darvas, Lucio Toma, Salvatore Guccione, Michael Nonnemacher, Rajakishore Mishra, Arianna Gelain, Lakshmi P. Kotra, Emil Pai
Publikováno v:
Medicinal Chemistry Research. 15:3-70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b289a55d73735a36b64a8179d246a2b2
https://doi.org/10.1007/s00044-006-1501-z
https://doi.org/10.1007/s00044-006-1501-z
Autor:
Emil Pai, Takeshi Nishino
Publikováno v:
Metal Ions in Biological Systems ISBN: 9780824707651
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ba8691cce1209b744cc709282691f3f
https://doi.org/10.1201/9780203909331.ch12
https://doi.org/10.1201/9780203909331.ch12
Autor:
Naveed Gulzar, Marinieve Montero, Kristina-Ana Klaric, Jason Donald, Shixia Wang, Christa Lepik, Sue Tsai, Sampson Wu, Jean-Philippe Julien, Ann Hessell, Shan Lu, Dennis Burton, Emil Pai, William DeGrado, Jamie Scott
Publikováno v:
The Journal of Immunology. 186:53.24-53.24
The limited success of vaccines targeting the MPER, a target of three broadly neutralizing (bNt) monoclonal antibodies (MAbs), we hypothesize, reflects the difficulty of mimicking the neutralization-competent structure (NCS) of the MPER. We determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3156f53de40a0314f12f2b0ae1300323
https://doi.org/10.4049/jimmunol.186.supp.53.24
https://doi.org/10.4049/jimmunol.186.supp.53.24
Publikováno v:
Europe PubMed Central
Ras (or p21) is the product of the ras proto-oncogene and is believed to be involved in growth-promoting signal transduction. The structure of the guanine nucleotide-binding domain of H-Ras (or p21H-ras) in the triphosphate conformation was determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::dde118438abb3a0326ffafbf09942b1b
https://pubmed.ncbi.nlm.nih.gov/8299426
https://pubmed.ncbi.nlm.nih.gov/8299426
Publikováno v:
The Journal of Immunology. 178:S12-S12
There is strong phylogenetic evidence that the immunoglobulin V genes that make a major contribution to the generation of diversity of our primary repertoire, are under selective pressure, perhaps by pathogens themselves. Here we report the X-ray cry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::193fc48df58c5a1fd89852811f18cf95
https://doi.org/10.4049/jimmunol.178.supp.35.53
https://doi.org/10.4049/jimmunol.178.supp.35.53
Autor:
Kotra Lakshmi, P., Emil Pai
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::15d8eca1b77f9d7fdd3f23332a86b507
http://europepmc.org/patents/pat/WO2007038860
http://europepmc.org/patents/pat/WO2007038860
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::00c5ba3d5c70ee2efde23e553c280bb2
http://europepmc.org/patents/pat/CA2665370
http://europepmc.org/patents/pat/CA2665370
Autor:
Serrano S, Araujo A, Apellániz B, Bryson S, Carravilla P, De la Arada I, Huarte N, Rujas E, Emil Pai, Jl, Arrondo, Domene C, Ma, Jiménez, Jl, Nieva
Publikováno v:
Europe PubMed Central
Serrano, S, Araujo, A, Apellaniz, B, Bryson, S, Carravilla, P, de la Arada, I, Huarte, N, Rujas, E, Pai, E F, Arrondo, J L R, Domene, C, Angeles Jimenez, M & Nieva, J L 2014, ' Structure and Immunogenicity of a Peptide Vaccine, Including the Complete HIV-1 gp41 2F5 Epitope : IMPLICATIONS FOR ANTIBODY RECOGNITION MECHANISM AND IMMUNOGEN DESIGN ', Journal of Biological Chemistry, vol. 289, no. 10, pp. 6565-6580 . https://doi.org/10.1074/jbc.M113.527747
Digital.CSIC. Repositorio Institucional del CSIC
instname
Serrano, S, Araujo, A, Apellaniz, B, Bryson, S, Carravilla, P, de la Arada, I, Huarte, N, Rujas, E, Pai, E F, Arrondo, J L R, Domene, C, Angeles Jimenez, M & Nieva, J L 2014, ' Structure and Immunogenicity of a Peptide Vaccine, Including the Complete HIV-1 gp41 2F5 Epitope : IMPLICATIONS FOR ANTIBODY RECOGNITION MECHANISM AND IMMUNOGEN DESIGN ', Journal of Biological Chemistry, vol. 289, no. 10, pp. 6565-6580 . https://doi.org/10.1074/jbc.M113.527747
Digital.CSIC. Repositorio Institucional del CSIC
instname
Background: HIV-1 vaccines should elicit broadly neutralizing antibodies as the gp41 >membrane-proximal external region> targeting MAb2F5. Results: NMR disclosed unprecedented 2F5 peptide-epitope structures. Although overall conformation was preserve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9c5fdc1a88b2985019c80a3644f274c4
http://europepmc.org/abstract/med/24429284
http://europepmc.org/abstract/med/24429284
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4e14485122287a0bb502ce0cb973be6d
http://europepmc.org/patents/pat/EP1203017
http://europepmc.org/patents/pat/EP1203017