Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Emil F. Khisamutdinov"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4797 (2023)
Nucleic acid-based therapeutics involves the conjugation of small molecule drugs to nucleic acid oligomers to surmount the challenge of solubility, and the inefficient delivery of these drug molecules into cells. “Click” chemistry has become popu
Externí odkaz:
https://doaj.org/article/68bc76c81dda4851bc9f0bed992d02e6
Autor:
M. Brittany Johnson, Justin R. Halman, Amanda R. Burmeister, Saralynn Currin, Emil F. Khisamutdinov, Kirill A. Afonin, Ian Marriott
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-14 (2020)
Abstract Background Bacterial meningitis and meningoencephalitis are associated with devastating neuroinflammation. We and others have demonstrated the importance of glial cells in the initiation of immune responses to pathogens invading the central
Externí odkaz:
https://doaj.org/article/26c99022872b45349a379e37c90af880
Publikováno v:
Molecules, Vol 24, Iss 20, p 3740 (2019)
Nano-objects made of nucleic acids are becoming promising materials in the biomedical field. This is, in part, due to DNA and RNA self-assembly properties that can be accurately computed to fabricate various complex nanoarchitectures of 2D and 3D sha
Externí odkaz:
https://doaj.org/article/16cd05dca84d42bf840ae585318233f3
Publikováno v:
Nanomaterials, Vol 8, Iss 12, p 984 (2018)
RNA aptamers that bind non-fluorescent dyes and activate their fluorescence are highly sensitive, nonperturbing, and convenient probes in the field of synthetic biology. These RNA molecules, referred to as light-up aptamers, operate as molecular nano
Externí odkaz:
https://doaj.org/article/65e7cd220e0b41ef9bf3f4e78cce2690
Autor:
Roger Chammas, Lydia M. Contreras, Brittany Johnson, Peixuan Guo, Koen Breyne, Aliasger K. Salem, Nils G. Walter, Emil F. Khisamutdinov, Joanna Sztuba-Solinska, Marina A. Dobrovolskaia, Kirill A. Afonin, Morgan Chandler
Publikováno v:
ACS Nano
The International Society of RNA Nanotechnology and Nanomedicine (ISRNN) hosts an annual meeting series focused on presenting the latest research achievements involving RNA-based therapeutics and strategies, aiming to expand their current biomedical
Publikováno v:
Nucleic Acids Research
Sequence variation in a widespread, recurrent, structured RNA 3D motif, the Sarcin/Ricin (S/R), was studied to address three related questions: First, how do the stabilities of structured RNA 3D motifs, composed of non-Watson–Crick (non-WC) basepai
Publikováno v:
DNA- and RNA-Based Computing Systems
Autor:
Daniel K. Miller, Joseph S Cooper, Emil F. Khisamutdinov, Morgan Brittany Johnson, Justin R. Halman, Ian Marriott, Kirill A. Afonin
Publikováno v:
Nucleic Acids Research
Nucleic acid nanoparticles (NANPs) have become powerful new platforms as therapeutic and diagnostic tools due to the innate biological ability of nucleic acids to identify target molecules or silence genes involved in disease pathways. However, the c
Autor:
Rabah N. Alsulami, Larry Sallans, Emil F. Khisamutdinov, U. Pandey, Ksenija Glusac, R. Marshall Wilson
Publikováno v:
Journal of Photochemistry and Photobiology A: Chemistry. 376:224-237
Pyrene-4,5-dione (pyrene quinone, PQ 1) is a polycyclic aromatic hydrocarbon (PAH), a planar group and DNA-cutting functionality that can cause cytotoxic, mutagenic, and carcinogenic damage to DNA and can encourage cancers in humans. It is extensivel
Autor:
Weina Ke, Renata F. Saito, Marina A. Dobrovolskaia, Roger Chammas, Jian Wang, Emil F. Khisamutdinov, Enping Hong, Martin Panigaj, Kirill A. Afonin, Mathias Viard, Nikolay V. Dokholyan, Melina Richardson, Maria Cristina Rangel
Publikováno v:
Nucleic Acids Research
Nucleic acid–based assemblies that interact with each other and further communicate with the cellular machinery in a controlled manner represent a new class of reconfigurable materials that can overcome limitations of traditional biochemical approa