Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Emil Degoma"'
Autor:
Emil DeGoma, MD
Publikováno v:
American Journal of Preventive Cardiology, Vol 19, Iss , Pp 100778- (2024)
Therapeutic Area: Pharmacologic Therapy Background: Subgroups of patients with atherosclerotic cardiovascular disease (ASCVD) remain at very high risk of major adverse cardiovascular and limb events despite lifestyle modification and intensive pharma
Externí odkaz:
https://doaj.org/article/adc09d54637847e98b13df444f506a12
Autor:
Gonzalo Tapia-Rico, Joanne Lundy, Gary Richardson, Niky Zhao, Karen Ebsworth, Huibin Yue, Shichiang Miao, Emil deGoma, Rita Jain, Thomas Schall, Kathleen Sullivan, Penglie Zhang, Paul de Souza
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Michael George, Andreas Kronbichler, Christian Pagnoux, Jason Springer, Kerstin W.A. Westman, Huibin Yue, Pirow Bekker, Emil Degoma, David Jayne, Peter Merkel
Publikováno v:
Nephrology Dialysis Transplantation. 37
BACKGROUND AND AIMS Standard therapy for ANCA-associated vasculitis (AAV) includes glucocorticoids (GC), which are associated with increased infections. Avacopan is an orally administered selective inhibitor of the C5a receptor recently approved for
Autor:
Gonzalo Tapia, Joanne Lundy, Gary Edward Richardson, Niky Zhao, Karen Ebsworth, Huibin Yue, Shichang Miao, Emil deGoma, Rita Jain, Thomas J. Schall, Kathleen Sullivan, Penglie Zhang, Paul L. de Souza
Publikováno v:
Journal of Clinical Oncology. 40:2593-2593
2593 Background: The novel small molecule CCX559 is a highly potent and selective PD-L1 inhibitor that induces the dimerization and internalization of cell-surface PD-L1. CCX559, when orally administered in animal models, demonstrated anti-tumor effi
Autor:
Ciara Marie Kelly, Cesar A. Perez, Cecilia Yeung, Laurel Sindelar, Theresa Medina, Steven J. O'Day, Melissa Amber Burgess, Montaser Shaheen, Leonel Hernandez-Aya, Robert Michel, Sunandana Chandra, Douglas Feltner, Ling Gao, Trisha Wise-Draper, Alice Bexon, Shailender Bhatia, Emil DeGoma, Weston L. Daniel, Glenn J. Hanna, Adil Daud, Martin Bexon, Mohammed M. Milhem, Douglas E Laux, Kimberly S. Smythe
Publikováno v:
Regular and young investigator award abstracts.
Background Spherical nucleic acids (SNAs) are nanostructures consisting of radially oriented, densely packed oligonucleotides arranged in a spherical 3D architecture. SNAs have different properties than linear oligonucleotides, including increased ce
Autor:
Harry Quon, Alexander Lin, Douglas Jacoby, Emil deGoma, Ali Javaheri, Jihane Hajj, Peter H. Ahn
Publikováno v:
Clinical Cardiology. 38:280-284
Background Radiation-treated head and neck cancer (HNC) patients are at high risk for developing radiation vasculopathy, as evidenced by an increased stroke risk. The benefits of screening and assessing the cardiovascular (CV) risk of HNC patients us
Autor:
Douglas, Jacoby, Jihane, Hajj, Ali, Javaheri, Emil, deGoma, Alexander, Lin, Peter, Ahn, Harry, Quon
Publikováno v:
Clinical cardiology. 38(5)
BACKGROUND: Radiation‐treated head and neck cancer (HNC) patients are at high risk for developing radiation vasculopathy, as evidenced by an increased stroke risk. The benefits of screening and assessing the cardiovascular (CV) risk of HNC patients
Publikováno v:
Transplantation. 66:89-95
Background. Little is known about the B-cell subsets that produce xenoreactive natural antibodies (NAb). This study was undertaken to investigate the potential role of varying B-cell populations in anti-pig NAb production in mice. Methods. Severe com
Autor:
John Wilkins, Neil Stone, Kiang Liu, Rachel Mackey, Emil DeGoma, Daniel Rader, Greg Burke, Donald M LLoyd-Jones
Publikováno v:
Circulation. 127
Despite the inverse association between HDL-C and CHD risk across HDL-C values of 20-80mg/dL CHD risk persists in people with very-high levels of HDL-C (> 80mg/dL). These risks may be explained by traditional risk factors and by structural and functi
Tolerization of anti-Galalpha1-3Gal natural antibody-forming B cells by induction of mixed chimerism
Autor:
Megan Sykes, John Iacomini, Yong-Guang Yang, A. Thall, Y. Xu, Hideki Ohdan, Jennifer L. Bracy, Emil deGoma
Publikováno v:
The Journal of Experimental Medicine
Xenotransplantation could overcome the severe shortage of allogeneic organs, a major factor limiting organ transplantation. Unfortunately, transplantation of organs from pigs, the most suitable potential donor species, results in hyperacute rejection