Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Emil C, Reisinger"'
Autor:
Tim A Dannenhaus, Franziska Winkelmann, Cindy Reinholdt, Miriam Bischofsberger, Jan Dvořák, Christoph G Grevelding, Micha Löbermann, Emil C Reisinger, Martina Sombetzki
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 10, p e0012615 (2024)
BackgroundSchistosoma mansoni was introduced from Africa to the Americas during the transatlantic slave trade and remains a major public health problem in parts of South America and the Caribbean. This study presents a comprehensive comparative analy
Externí odkaz:
https://doaj.org/article/5664e23471164957a6a581023dd547d8
Autor:
Veronica V. Rezelj, Fred Paddenburg, Marie Enajite Diegbe, Julius Nangosyah, Emil C. Reisinger, Weihong Hu, Carla Truyers, Gert Scheper, Mathieu Le Gars, Jenny Hendriks, Frank Struyf, Macaya Douoguih, Hanneke Schuitemaker, Javier Ruiz-Guiñazú
Publikováno v:
Vaccines, Vol 12, Iss 10, p 1136 (2024)
Background: This study aimed to support the end-of-shelf life specification (2.5 × 1010 virus particles [vp]) for the standard Ad26.COV2.S dose (5 × 1010 vp). Methods: This randomized, double-blind Phase 3 study evaluated immunogenicity, reactogeni
Externí odkaz:
https://doaj.org/article/54705ff51339487aa084bce5e1e25b60
Autor:
Franziska Woitschach, Marlen Kloss, Sabine Kischkel, Tomáš Macháček, Cindy Reinholdt, Volkmar Senz, Karsten Schlodder, Micha Löbermann, Niels Grabow, Emil C. Reisinger, Martina Sombetzki
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Introduction: The biocompatibility of an implanted material strongly determines the subsequent host immune response. After insertion into the body, each medical device causes tissue reactions. How intense and long-lasting these are is defined by the
Externí odkaz:
https://doaj.org/article/ff06b97bde04407c93e25de3955276ed
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundAfter licensing of the protein-based vaccine NVX-CoV2373, three technically different vaccines against the SARS-CoV-2 became available for application to the human population - and for comparison of efficacies.MethodsWe here recruited 42 st
Externí odkaz:
https://doaj.org/article/1ce225bf827240deb6bc84718f039e0b
Autor:
Miriam Bischofsberger, Cindy Reinholdt, Tim Alexander Dannenhaus, Johann Aleith, Wendy Bergmann-Ewert, Brigitte Müller-Hilke, Micha Löbermann, Emil C. Reisinger, Martina Sombetzki
Publikováno v:
Pathogens, Vol 12, Iss 12, p 1432 (2023)
While the lung is considered an efficient site for stopping the larvae of the acute Schistosoma spp. infection phase from migrating through extensive inflammatory responses in the surrounding tissues, little is known about these processes. To date, t
Externí odkaz:
https://doaj.org/article/dc4bcb103afd496e984133a837727a8e
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundUnderstanding the humoral immune response towards viral infection and vaccination is instrumental in developing therapeutic tools to fight and restrict the viral spread of global pandemics. Of particular interest are the specificity and bre
Externí odkaz:
https://doaj.org/article/5cbc6428565c45f8b655cafa0c80d26b
Autor:
Franziska Winkelmann, Manuela Gesell Salazar, Christian Hentschker, Stephan Michalik, Tomáš Macháček, Christian Scharf, Emil C. Reisinger, Uwe Völker, Martina Sombetzki
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The tegument, as the surface layer of adult male and female Schistosoma spp. represents the protective barrier of the worms to the hostile environment of the host bloodstream. Here we present the first comparative analysis of sex-specific te
Externí odkaz:
https://doaj.org/article/ed66621b100f493c86e5994e2d4f5cb2
Autor:
Michael Müller, Johann Volzke, Behnam Subin, Silke Müller, Martina Sombetzki, Emil C. Reisinger, Brigitte Müller-Hilke
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background While vaccination programs against the severe acute respiratory syndrome virus 2 (SARS-CoV-2) are globally ongoing, disparate strategies for the deployment of spike antigen show varying effectiveness. Methods In order to explore t
Externí odkaz:
https://doaj.org/article/8a6399a6f83645559eb0f13aadb3a634
Autor:
Cindy Reinholdt, Franziska Winkelmann, Nicole Koslowski, Emil C. Reisinger, Martina Sombetzki
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe complexity of the Schistosoma spp. life cycle and their effective immune evasion strategies, makes vaccine development challenging. Unisexual infection models, that excludes any immunomodulatory effects of the parasite eggs, may contr
Externí odkaz:
https://doaj.org/article/2793d572cc0b4290ab5dd4de29ec1f97
Autor:
Martina Sombetzki, Cindy Reinholdt, Franziska Winkelmann, Anne Rabes, Nicole Koslowski, Emil C. Reisinger
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
In exhibiting gonochorism and phenotypic sexual dimorphism, Schistosoma spp. are unique among trematodes. Only females mating with male schistosomes can produce the highly immunogenic parasite eggs which determine the clinical picture of the disease
Externí odkaz:
https://doaj.org/article/dd9a73cf8a4b45fcab27fa154389ba86