Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Emil, Jørsboe"'
Autor:
Ninna Karsbæk Senftleber, Kristine Skøtt Pedersen, Cecilie Schnoor Jørgensen, Hanne Pedersen, Marie Mathilde Bjerg Christensen, Emilie Kabel Madsen, Kristine Andersen, Emil Jørsboe, Matthew Paul Gillum, Michael Bom Frøst, Torben Hansen, Marit Eika Jørgensen
Publikováno v:
International Journal of Circumpolar Health, Vol 82, Iss 1 (2023)
ABSTRACTIn Greenland, traditional marine foods are increasingly being replaced by sucrose- and starch-rich foods. A knock-out c.273_274delAG variant in the sucrase-isomaltase (SI) gene is relatively common in Greenland, with homozygous carriers being
Externí odkaz:
https://doaj.org/article/32a54b5072174977b2084fe1d15aac67
Autor:
Emil Jørsboe, Anders Albrechtsen
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 12, Iss 1 (2021)
AbstractAssociation studies using genetic data from SNP-chip-based imputation or low-depth sequencing data provide a cost-efficient design for large-scale association studies. We explore methods for performing association studies applicable to such g
Externí odkaz:
https://doaj.org/article/14c799f5ee694de0a213c9b1fb797d02
Autor:
Rute R. da Fonseca, Irene Ureña, Sandra Afonso, Ana Elisabete Pires, Emil Jørsboe, Lounès Chikhi, Catarina Ginja
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background Iberian primitive breeds exhibit a remarkable phenotypic diversity over a very limited geographical space. While genomic data are accumulating for most commercial cattle, it is still lacking for these primitive breeds. Whole genom
Externí odkaz:
https://doaj.org/article/e61739b8b4424a0e995547702f603413
Autor:
Mette K Andersen, Emil Jørsboe, Line Skotte, Kristian Hanghøj, Camilla H Sandholt, Ida Moltke, Niels Grarup, Timo Kern, Yuvaraj Mahendran, Bolette Søborg, Peter Bjerregaard, Christina V L Larsen, Inger K Dahl-Petersen, Hemant K Tiwari, Bjarke Feenstra, Anders Koch, Howard W Wiener, Scarlett E Hopkins, Oluf Pedersen, Mads Melbye, Bert B Boyer, Marit E Jørgensen, Anders Albrechtsen, Torben Hansen
Publikováno v:
PLoS Genetics, Vol 16, Iss 1, p e1008544 (2020)
The genetic architecture of the small and isolated Greenlandic population is advantageous for identification of novel genetic variants associated with cardio-metabolic traits. We aimed to identify genetic loci associated with body mass index (BMI), t
Externí odkaz:
https://doaj.org/article/31a1e3c4b2684f3ca2c1fe7ceb71c161
Autor:
Ninna Senftleber, Mette Andersen, Emil Jørsboe, Frederik Stæger, Anne Nøhr, Genis Garcia-Erill, Jonas Meisner, Cindy Santander, Renzo Balboa, Arthur Gilly, Peter Bjerregaard, Christina Larsen, Niels Grarup, Marit Jørgensen, Eleftheria Zeggini, Ida Moltke, Torben Hansen, Anders Albrechtsen
Perturbation of lipid homeostasis is a major risk factor for cardiovascular disease (CVD), the leading cause of death worldwide. We aimed to identify genetic variants affecting lipid levels, and thereby risk of CVD, in Greenlanders. Genome-wide assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3448dc1df5e47ae2f1628b8977363b54
https://doi.org/10.21203/rs.3.rs-2633131/v1
https://doi.org/10.21203/rs.3.rs-2633131/v1
Autor:
Anne Cathrine Baun Thuesen, Frederik Filip Stæger, Alba Kaci, Marie Holm Solheim, Ingvild Aukrust, Emil Jørsboe, Cindy G. Santander, Mette K. Andersen, Zilong Li, Arthur Gilly, Sara Elizabeth Stinson, Anette Prior Gjesing, Peter Bjerregaard, Michael Lynge Pedersen, Christina Viskum Lytken Larsen, Niels Grarup, Marit E. Jørgensen, Eleftheria Zeggini, Lise Bjørkhaug, Pål Rasmus Njølstad, Anders Albrechtsen, Ida Moltke, Torben Hansen
Publikováno v:
The Lancet Regional Health-Europe
Thuesen, A C B, Stæger, F F, Kaci, A, Solheim, M H, Aukrust, I, Jørsboe, E, Santander, C G, Andersen, M K, Li, Z, Gilly, A, Stinson, S E, Gjesing, A P, Bjerregaard, P, Pedersen, M L, Larsen, C V L, Grarup, N, Jørgensen, M E, Zeggini, E, Bjørkhaug, L, Njølstad, P R, Albrechtsen, A, Moltke, I & Hansen, T 2023, ' A novel splice-affecting HNF1A variant with large population impact on diabetes in Greenland ', The Lancet Regional Health-Europe, vol. 24, 100529 . https://doi.org/10.1016/j.lanepe.2022.100529
Thuesen, A C B, Stæger, F F, Kaci, A, Solheim, M H, Aukrust, I, Jørsboe, E, Santander, C G, Andersen, M K, Li, Z, Gilly, A, Stinson, S E, Gjesing, A P, Bjerregaard, P, Pedersen, M L, Larsen, C V L, Grarup, N, Jørgensen, M E, Zeggini, E, Bjørkhaug, L, Njølstad, P R, Albrechtsen, A, Moltke, I & Hansen, T 2023, ' A novel splice-affecting HNF1A variant with large population impact on diabetes in Greenland ', The Lancet Regional Health-Europe, vol. 24, 100529 . https://doi.org/10.1016/j.lanepe.2022.100529
Background: The genetic disease architecture of Inuit includes a large number of common high-impact variants. Identification of such variants contributes to our understanding of the genetic aetiology of diseases and improves global equity in genomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630bbe59ff3adfcfcc41cec4442f73bb
https://hdl.handle.net/11250/3063542
https://hdl.handle.net/11250/3063542
Autor:
Xi Wang, Casper-Emil Tingskov Pedersen, Georgios Athanasiadis, Genis Garcia-Erill, Kristian Hanghøj, Laura D. Bertola, Malthe Sebro Rasmussen, Mikkel Schubert, Xiaodong Liu, Zilong Li, Long Lin, Emil Jørsboe, Casia Nursyifa, Shanlin Liu, Vincent Muwanika, Charles Masembe, Lei Chen, Wen Wang, Ida Moltke, Hans R. Siegismund, Anders Albrechtsen, Rasmus Heller
African antelope diversity is a globally unique vestige of a much richer world-wide Pleistocene megafauna. Despite this, the evolutionary processes leading to the prolific radiation of African antelopes are not well understood. Here, we sequenced 145
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8e950f85787262372cea46d05071898
https://doi.org/10.1101/2022.12.08.519574
https://doi.org/10.1101/2022.12.08.519574
Autor:
Mette K. Andersen, Line Skotte, Emil Jørsboe, Ryan Polito, Frederik F. Stæger, Peter Aldiss, Kristian Hanghøj, Ryan K. Waples, Cindy G. Santander, Niels Grarup, Inger K. Dahl-Petersen, Lars J. Diaz, Maria Overvad, Ninna K. Senftleber, Bolette Søborg, Christina V.L. Larsen, Clara Lemoine, Oluf Pedersen, Bjarke Feenstra, Peter Bjerregaard, Mads Melbye, Marit E. Jørgensen, Nils J. Færgeman, Anders Koch, Thomas Moritz, Matthew P. Gillum, Ida Moltke, Torben Hansen, Anders Albrechtsen
Publikováno v:
Andersen, M K, Skotte, L, Jørsboe, E, Polito, R, Stæger, F F, Aldiss, P, Hanghøj, K, Waples, R K, Santander, C G, Grarup, N, Dahl-Petersen, I K, Diaz, L J, Overvad, M, Senftleber, N K, Søborg, B, Larsen, C V L, Lemoine, C, Pedersen, O, Feenstra, B, Bjerregaard, P, Melbye, M, Jørgensen, M E, Færgeman, N J, Koch, A, Moritz, T, Gillum, M P, Moltke, I, Hansen, T & Albrechtsen, A 2022, ' Loss of Sucrase-Isomaltase Function Increases Acetate Levels and Improves Metabolic Health in Greenlandic Cohorts ', Gastroenterology, vol. 162, no. 4, pp. 1171-1182.e3 . https://doi.org/10.1053/j.gastro.2021.12.236
Andersen, M K, Skotte, L, Jørsboe, E, Polito, R, Stæger, F F, Aldiss, P, Hanghøj, K, Waples, R K, Santander, C G, Grarup, N, Dahl-Petersen, I K, Diaz, L J, Overvad, M, Senftleber, N K, Søborg, B, Larsen, C V L, Lemoine, C, Pedersen, O, Feenstra, B, Bjerregaard, P, Melbye, M, Jørgensen, M E, Færgeman, N J, Koch, A, Moritz, T, Gillum, M P, Moltke, I, Hansen, T & Albrechtsen, A 2022, ' Loss of sucrase-isomaltase function increases acetate levels and improves metabolic health in Greenlandic cohorts ', Gastroenterology, vol. 162, no. 4, pp. 1171-1182.e3 . https://doi.org/10.1053/j.gastro.2021.12.236
Andersen, M K, Skotte, L, Jørsboe, E, Polito, R, Stæger, F F, Aldiss, P, Hanghøj, K, Waples, R K, Santander, C G, Grarup, N, Dahl-Petersen, I K, Diaz, L J, Overvad, M, Senftleber, N K, Søborg, B, Larsen, C V L, Lemoine, C, Pedersen, O, Feenstra, B, Bjerregaard, P, Melbye, M, Jørgensen, M E, Færgeman, N J, Koch, A, Moritz, T, Gillum, M P, Moltke, I, Hansen, T & Albrechtsen, A 2022, ' Loss of sucrase-isomaltase function increases acetate levels and improves metabolic health in Greenlandic cohorts ', Gastroenterology, vol. 162, no. 4, pp. 1171-1182.e3 . https://doi.org/10.1053/j.gastro.2021.12.236
BACKGROUND & AIMS: The sucrase-isomaltase (SI) c.273_274delAG loss-of-function variant is common in Arctic populations and causes congenital sucrase-isomaltase deficiency, which is an inability to break down and absorb sucrose and isomaltose. Childre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af598bb6586cd15c453ff65560389ba
https://findresearcher.sdu.dk:8443/ws/files/202400420/PIIS0016508521040658.pdf
https://findresearcher.sdu.dk:8443/ws/files/202400420/PIIS0016508521040658.pdf
Autor:
Mette Korre Andersen, Emil Jørsboe, Camilla Helene Sandholt, Niels Grarup, Marit Eika Jørgensen, Nils Joakim Færgeman, Peter Bjerregaard, Oluf Pedersen, Ida Moltke, Torben Hansen, Anders Albrechtsen
Publikováno v:
PLoS Genetics, Vol 12, Iss 6, p e1006119 (2016)
Fatty acids (FAs) are involved in cellular processes important for normal body function, and perturbation of FA balance has been linked to metabolic disturbances, including type 2 diabetes. An individual's level of FAs is affected by diet, lifestyle,
Externí odkaz:
https://doaj.org/article/0f366d3581b4436284fe88295971178d
Autor:
Emil, Jørsboe, Mette K, Andersen, Line, Skotte, Frederik F, Stæger, Nils J, Færgeman, Kristian, Hanghøj, Cindy G, Santander, Ninna K, Senftleber, Lars J, Diaz, Maria, Overvad, Ryan K, Waples, Frank, Geller, Peter, Bjerregaard, Mads, Melbye, Christina V L, Larsen, Bjarke, Feenstra, Anders Koch, Marit E, Jørgensen, Niels, Grarup, Ida, Moltke, Anders, Albrechtsen, Torben, Hansen
Publikováno v:
HGG advances. 3(4)
The common Arctic-specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0086f96edaf9650dc6bebe1b990690f8
https://pubmed.ncbi.nlm.nih.gov/36267056
https://pubmed.ncbi.nlm.nih.gov/36267056