Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Emil, Frantík"'
Autor:
Igor Linhart, Petr Mikeš, Václav Šístek, Antonín Králík, Emil Frantík, Jan Krouželka, Jaroslav Mráz
Publikováno v:
Journal of Applied Toxicology. 33:516-520
Metabolism of benzene, an important environmental and industrial carcinogen, produces three electrophilic intermediates, namely, benzene oxide and 1,2- and 1,4-benzoquinone, capable of reacting with the DNA. Numerous DNA adducts formed by these metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bb581ca8cbaec0926a66776785260bc
https://doi.org/10.1002/jat.2716
https://doi.org/10.1002/jat.2716
Publikováno v:
Toxicology Letters. 205:273-278
Among numerous adducts formed by reaction of DNA with p-benzoquinone (p-BQ), an electrophilic metabolite of benzene, only N2-(4-hydroxyphenyl)guanine (N2HPG) has been confirmed in vivo. If excreted in urine N2HPG would be a candidate non-invasive bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df47a838d57f0c9e6e4a16d59a751a85
https://doi.org/10.1016/j.toxlet.2011.06.016
https://doi.org/10.1016/j.toxlet.2011.06.016
Autor:
Emil Frantík, Lenka Neufussová, Marek Kořínek, Ľudmila Vodičková, Petr Mikeš, Igor Linhart, Jan Krouželka
Publikováno v:
Toxicology Letters. 184:33-37
New urinary adenine adducts, 3-(2-hydroxy-1-phenylethyl)adenine (N3alphaA), 3-(2-hydroxy-2-phenylethyl)adenine (N3betaA), were found in the urine of mice exposed to styrene vapour. These styrene 7,8-oxide derived adenine adducts as well as previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef032ccc647f3faf4ed90c704ab3ea1
https://doi.org/10.1016/j.toxlet.2008.10.010
https://doi.org/10.1016/j.toxlet.2008.10.010
Autor:
Miroslava Hornychová, Max Vojtíšek, Emil Frantík, Eva Švandová, Lucie Kašparová, Jana Knotková
Publikováno v:
Electromagnetic Biology and Medicine. 24:355-358
Rats were experimentally exposed to the chemical factor, inorganic manganese (Mn), and the physical factor, simulated radiation of mobile phone to detect possible interactions, resulting in changes of brain Mn level or other changes. In acute test, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e50b2633d84d52cba63dc5f04a43a3e
https://doi.org/10.1080/15368370500381695
https://doi.org/10.1080/15368370500381695
Publikováno v:
Chemico-Biological Interactions. 115:53-70
We studied metabolism of monochlorobenzene (MCB), 1,2-dichlorobenzene (1,2-DCB) and 1,4-DCB in liver microsomes from untreated male and female Wistar rats and B6C3F1 mice or in those after the induction of CYP3A or 2E1 as well as in human male liver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0acd4e56f5f752cae7a7f0e5dcd24003
https://doi.org/10.1016/s0009-2797(98)00058-1
https://doi.org/10.1016/s0009-2797(98)00058-1
Publikováno v:
International Journal of Behavioral Medicine. 5:281-294
In this study, cardiovascular (CV) response to a standard laboratory challenge was compared to 24-hr noninvasive monitoring of heart rate (HR) and blood pressure (BP) in 30 healthy middle-aged train drivers. Laboratory stress test consisted of the or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8da5d02e4a33739788fb8def63d2972
https://doi.org/10.1207/s15327558ijbm0504_3
https://doi.org/10.1207/s15327558ijbm0504_3
Autor:
Petr, Mikeš, Václav, Sístek, Jan, Krouželka, Antonín, Králík, Emil, Frantík, Jaroslav, Mráz, Igor, Linhart
Publikováno v:
Journal of applied toxicology : JAT. 33(6)
Metabolism of benzene, an important environmental and industrial carcinogen, produces three electrophilic intermediates, namely, benzene oxide and 1,2- and 1,4-benzoquinone, capable of reacting with the DNA. Numerous DNA adducts formed by these metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::48d8f0c6abd4808aba7fc65473bef4db
https://pubmed.ncbi.nlm.nih.gov/22336960
https://pubmed.ncbi.nlm.nih.gov/22336960
Autor:
Jaroslav Mráz, Emil Frantík, Alexandra Šilhánková, Michal Himl, Igor Linhart, Iveta Hanzlíková
Publikováno v:
Toxicology letters. 208(3)
3-Nitrobenzanthrone (3-NBA) is an extremely potent mutagen and suspect human carcinogen found in diesel exhaust. Its isomer 2-nitrobenzanthrone (2-NBA) has also been found in ambient air. These isomers differ in mutagenicity in Salmonella by 2-3 orde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::502d57251bf5dbddbdd6b7dbe27d3902
https://pubmed.ncbi.nlm.nih.gov/22143054
https://pubmed.ncbi.nlm.nih.gov/22143054
Publikováno v:
Toxicology letters. 205(3)
Among numerous adducts formed by reaction of DNA with p-benzoquinone (p-BQ), an electrophilic metabolite of benzene, only N2-(4-hydroxyphenyl)guanine (N2HPG) has been confirmed in vivo. If excreted in urine N2HPG would be a candidate non-invasive bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f33f0aaa133eea90443657630b07f94d
https://pubmed.ncbi.nlm.nih.gov/21718765
https://pubmed.ncbi.nlm.nih.gov/21718765
Autor:
Eva Švandová, Max Vojtíšek, Jana Pátková, Miroslava Hornychová, Lucie Kašparová, Jana Knotková, Emil Frantík, Jaroslav Formanek
Publikováno v:
Interdisciplinary Toxicology
Impact of metal in vitro administration on rat tissue oxygen consumption is referred in the first part. Toxicological implications of in vivo metal administration to rats and the study of potential penetration of metal into the rat brain, which may e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdb477b7f18c055a56db2ad25e4f7cfc
https://doi.org/10.2478/v10102-010-0039-6
https://doi.org/10.2478/v10102-010-0039-6