Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Emil, Bulatov"'
Autor:
Vitaly Chasov, Irina Ganeeva, Ekaterina Zmievskaya, Damir Davletshin, Elvina Gilyazova, Aygul Valiullina, Emil Bulatov
Publikováno v:
Cells, Vol 13, Iss 15, p 1282 (2024)
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the joints. Although much remains unknown about the pathogenesis of RA, there is evidence that impaired immune tolerance and the development of RA are related
Externí odkaz:
https://doaj.org/article/346e936d826c4b19909f0fb9811c0c36
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Asymmetric cell division is a fundamental process conserved throughout evolution, employed by both prokaryotic and eukaryotic organisms. Its significance lies in its ability to govern cell fate and facilitate the generation of diverse cell types. The
Externí odkaz:
https://doaj.org/article/911a14fa62d54a9f9274d26f41ba6c5e
Autor:
Vitaly Chasov, Ekaterina Zmievskaya, Irina Ganeeva, Elvina Gilyazova, Damir Davletshin, Marat Khaliulin, Emmanuel Kabwe, Yuriy N. Davidyuk, Aygul Valiullina, Albert Rizvanov, Emil Bulatov
Publikováno v:
Antibodies, Vol 13, Iss 1, p 10 (2024)
Systemic autoimmune diseases (SAIDs), such as systemic lupus erythematosus (SLE), systemic sclerosis (SSc) and rheumatoid arthritis (RA), are fully related to the unregulated innate and adaptive immune systems involved in their pathogenesis. They hav
Externí odkaz:
https://doaj.org/article/0e9050511ea84f99a02fdf8d1f3fd5c1
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
FOXP1 is ubiquitously expressed in the human body and is implicated in both physiological and pathological processes including cancer. However, despite its importance the role of FOXP1 in T-cells has not been extensively studied. Although relatively
Externí odkaz:
https://doaj.org/article/95353c74a5cb4f27b978109b5c8e2ea5
Autor:
Diana Mironova, Egor Makarov, Islamiya Bilyukova, Kevser Akyol, Elsa Sultanova, Vladimir Evtugyn, Damir Davletshin, Elvina Gilyazova, Emil Bulatov, Vladimir Burilov, Svetlana Solovieva, Igor Antipin
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 699 (2023)
The present work focuses on the study of the aggregation and complexing properties of calixarenes as potential DNA condensation agents for gene delivery. In the current study, 1,4-triazole derivatives of calix[4]arenes 7 and 8 containing monoammonium
Externí odkaz:
https://doaj.org/article/1b934f67017e4f84ade83437b7b77a40
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 1, Iss 5, Pp 381-390 (2020)
Proteolysis targeting chimeras (PROTACs) represent a promising class of hetero-bivalent molecules that facilitate ubiquitination of a target protein by simultaneously binding and bringing together both the E3 enzyme and the target. These compounds co
Externí odkaz:
https://doaj.org/article/9a06b728447345078d34cb97f4536f0c
Recent Advances in the Development of Bioreactors for Manufacturing of Adoptive Cell Immunotherapies
Autor:
Irina Ganeeva, Ekaterina Zmievskaya, Aygul Valiullina, Anna Kudriaeva, Regina Miftakhova, Alexey Rybalov, Emil Bulatov
Publikováno v:
Bioengineering, Vol 9, Iss 12, p 808 (2022)
Harnessing the human immune system as a foundation for therapeutic technologies capable of recognizing and killing tumor cells has been the central objective of anti-cancer immunotherapy. In recent years, there has been an increasing interest in impr
Externí odkaz:
https://doaj.org/article/2225cc2722504eceb4b3b04ec10891de
Autor:
Raniya Khadiullina, Regina Mirgayazova, Damir Davletshin, Elvina Khusainova, Vitaly Chasov, Emil Bulatov
Publikováno v:
Life, Vol 13, Iss 1, p 31 (2022)
The p53 protein is a transcription factor that preserves the integrity of the genome. The TP53 gene has inactivating mutations in about 50% of all human cancers. Some missense mutations lead to decreased thermal stability in the p53 protein, its unfo
Externí odkaz:
https://doaj.org/article/04499f76dc52404cae4f9ab0b9ebbdd9
Autor:
Vitaly Chasov, Mikhail Zaripov, Regina Mirgayazova, Raniya Khadiullina, Ekaterina Zmievskaya, Irina Ganeeva, Aigul Valiullina, Albert Rizvanov, Emil Bulatov
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Transcription factor and oncosuppressor protein p53 is considered as one of the most promising molecular targets that remains a high-hanging fruit in cancer therapy. TP53 gene encoding the p53 protein is known to be the most frequently mutated gene i
Externí odkaz:
https://doaj.org/article/015ab42fba0640eaaca97c4a71907b72
Autor:
Vitaly Chasov, Regina Mirgayazova, Ekaterina Zmievskaya, Raniya Khadiullina, Aygul Valiullina, Joseph Stephenson Clarke, Albert Rizvanov, Matthias G. J. Baud, Emil Bulatov
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The transcription factor p53 is a key tumor suppressor that is inactivated in almost all cancers due to either point mutations in the TP53 gene or overexpression of its negative regulators. The p53 protein is known as the “cellular gatekeeper” fo
Externí odkaz:
https://doaj.org/article/bd5dac044856409a9eb9ccd1aa8db9b8