Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Emiko Sugikawa"'
Publikováno v:
Biochemical and Biophysical Research Communications. 334:987-995
We have previously identified a Galpha(i/o)-protein-coupled receptor (TG1019/OXE) using 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-oxo-ETE) as its ligand. We investigated signal transduction from TG1019 following stimulation with 5-oxo-ETE and role
Publikováno v:
Biochemical and Biophysical Research Communications. 261:256-263
The tumor suppressor protein p53 is a phosphoprotein and has growth and transformation suppression functions. Phosphorylation of wild-type p53 is known to modulate its function. To investigate the role of phosphorylation in modulating the functions o
Autor:
Takeshi Hosoi, Yutaka Koguchi, Aiko Chikada, Koji Ogawa, Naoki Suto, Emiko Sugikawa, Tetsuo Ohnuki, Shiho Tsunoda, Tomoyasu Taniguchi, Naoki Tsuda
Publikováno v:
The Journal of biological chemistry. 277(35)
We have conducted an in silico data base search for and cloned a novel G-protein-coupled receptor (GPCR) named TG1019. Dot and Northern blotting analyses showed that transcripts of the novel GPCR were expressed in various tissues except brain, and th
Publikováno v:
Japanese Journal of Cancer Research : Gann
Abnormality of p53, a tumor suppressor gene, is considered to be a potential cause of malignancy. We found that ellipticine and 9-hydroxyellipticine (9HE), antitumor alkaloids, caused selective inhibition of p53 protein phosphorylation in Lewis lung