Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Emiko Fukumoto"'
Autor:
Aya Yamada, Keigo Yoshizaki, Masaki Ishikawa, Kan Saito, Yuta Chiba, Emiko Fukumoto, Ryoko Hino, Seira Hoshikawa, Mitsuki Chiba, Takashi Nakamura, Tsutomu Iwamoto, Satoshi Fukumoto
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Connexin 43 (Cx43) is an integral membrane protein that forms gap junction channels. These channels mediate intercellular transport and intracellular signaling to regulate organogenesis. The human disease oculodentodigital dysplasia (ODDD) is caused
Externí odkaz:
https://doaj.org/article/4e5fca03eefa43658dfd38714e622578
Autor:
Kan Saito, Frederic Michon, Aya Yamada, Hiroyuki Inuzuka, Satoko Yamaguchi, Emiko Fukumoto, Keigo Yoshizaki, Takashi Nakamura, Makiko Arakaki, Yuta Chiba, Masaki Ishikawa, Hideyuki Okano, Irma Thesleff, Satoshi Fukumoto
Publikováno v:
iScience, Vol 23, Iss 7, Pp 101329- (2020)
Summary: The transcription factor Sox21 is expressed in the epithelium of developing teeth. The present study aimed to determine the role of Sox21 in tooth development. We found that disruption of Sox21 caused severe enamel hypoplasia, regional osteo
Externí odkaz:
https://doaj.org/article/b8f5cb3372324ed98382e503ff281643
Autor:
Satoshi Fukumoto, Takashi Nakamura, Aya Yamada, Makiko Arakaki, Kan Saito, Juan Xu, Emiko Fukumoto, Yoshihiko Yamada
Publikováno v:
Japanese Dental Science Review, Vol 50, Iss 2, Pp 47-54 (2014)
Ameloblasts secrete enamel matrix proteins, including amelogenin, ameloblastin, enamelin, amelotin, and Apin/odontogenic ameloblast-associated protein (Apin/ODAM). Amelogenin is the major protein component of the enamel matrix. Amelogenin, ameloblast
Externí odkaz:
https://doaj.org/article/32902873da394141aaaa74340ec87816
Autor:
Kan Saito, Emiko Fukumoto, Aya Yamada, Kenji Yuasa, Keigo Yoshizaki, Tsutomu Iwamoto, Masahiro Saito, Takashi Nakamura, Satoshi Fukumoto
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0121667 (2015)
The dental epithelium and extracellular matrix interact to ensure that cell growth and differentiation lead to the formation of teeth of appropriate size and quality. To determine the role of fibronectin in differentiation of the dental epithelium an
Externí odkaz:
https://doaj.org/article/96c753759b114c13a51739ba05de0279
Autor:
Satoshi Fukumoto, Tsutomu Iwamoto, Eiko Sakai, Kenji Yuasa, Emiko Fukumoto, Aya Yamada, Tomokazu Hasegawa, Kazuaki Nonaka, Yuzo Kato
Publikováno v:
Journal of Pharmacological Sciences, Vol 100, Iss 3, Pp 195-200 (2006)
Abstract.: Glycosphingolipids are thought to play important roles in the development and function of several tissues, although the function of glycolipids in osteoclastogenesis has not been clearly demonstrated. In the present study, D-threo-1-phenyl
Externí odkaz:
https://doaj.org/article/eb5292e9c8c6408cbef48820f194a10c
Autor:
Manami Tadano, Yasunori Matsunaga, Kan Saito, Yuria Suzuki, Tomoaki Nakamura, Seira Hoshikawa, Mitsuki Chiba, Ryoko Hino, Yuriko Maruya, Emiko Fukumoto, Aya Yamada, Satoshi Fukumoto
Publikováno v:
Pediatric Dental Journal.
Autor:
Yuriko Maruya, Tsutomu Iwamoto, Hidemistu Harada, Aya Yamada, Keishi Otsu, Keigo Yoshizaki, Ryoko Hino, Kan Saito, Satoshi Fukumoto, Emiko Fukumoto, Yuta Chiba
Publikováno v:
Pediatric Dental Journal. 30:208-214
Background Filamin-A (FLNA) is one of the adaptor proteins binding to both integrin beta chain and actin filament. Several kind of mutation in human FLNA gene were observed in Melnick-Needles syndrome (MNS). However, the role of FLNA in tooth formati
Autor:
Masaki Ishikawa, Takashi Nakamura, Hideyuki Okano, Keigo Yoshizaki, Hiroyuki Inuzuka, Kan Saito, Makiko Arakaki, Emiko Fukumoto, Satoko Yamaguchi, Satoshi Fukumoto, Frederic Michon, Aya Yamada, Yuta Chiba, Irma Thesleff
Publikováno v:
iScience, Vol 23, Iss 7, Pp 101329-(2020)
iScience
iScience
Summary The transcription factor Sox21 is expressed in the epithelium of developing teeth. The present study aimed to determine the role of Sox21 in tooth development. We found that disruption of Sox21 caused severe enamel hypoplasia, regional osteop
Publikováno v:
Genes to Cells. 22:360-375
Geminin is implicated in regulation of the cell cycle and differentiation. Although loss of Geminin triggers unscheduled DNA rereplication as a result of interruption of its interaction with Cdt1 in some somatic cancer cells, whether such cell cycle
Autor:
Keita Funada, Satoshi Fukumoto, Tsutomu Iwamoto, Ichiro Takahashi, Naoto Haruyama, Aya Yamada, Kanako Miyazaki, Kan Saito, Emiko Fukumoto, Xue Han, Chieko Arai, Keigo Yoshizaki
Publikováno v:
Scientific Reports
Tooth development is initiated by epithelial-mesenchymal interactions via basement membrane (BM) and growth factors. In the present study, we found that nephronectin (Npnt), a component of the BM, is highly expressed in the developing tooth. Npnt loc