Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Emiko Desvaux"'
Antibody-mediated neutralization of galectin-3 as a strategy for the treatment of systemic sclerosis
Autor:
Céline Ortega-Ferreira, Perrine Soret, Gautier Robin, Silvia Speca, Sandra Hubert, Marianne Le Gall, Emiko Desvaux, Manel Jendoubi, Julie Saint-Paul, Loubna Chadli, Agnès Chomel, Sylvie Berger, Emmanuel Nony, Béatrice Neau, Benjamin Fould, Anne Licznar, Franck Levasseur, Thomas Guerrier, Sahar Elouej, Sophie Courtade-Gaïani, Nicolas Provost, The Quyen Nguyen, Julien Verdier, David Launay, Frédéric De Ceuninck
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Systemic sclerosis (SSc) is an autoimmune, inflammatory and fibrotic disease with limited treatment options. Developing new therapies is therefore crucial to address patient needs. To this end, we focused on galectin-3 (Gal-3), a lectin know
Externí odkaz:
https://doaj.org/article/b4ac4a8d08c9436badd6ef4d718b8e03
A new molecular classification to drive precision treatment strategies in primary Sjögren’s syndrome
Autor:
Perrine Soret, Christelle Le Dantec, Emiko Desvaux, Nathan Foulquier, Bastien Chassagnol, Sandra Hubert, Christophe Jamin, Guillermo Barturen, Guillaume Desachy, Valérie Devauchelle-Pensec, Cheïma Boudjeniba, Divi Cornec, Alain Saraux, Sandrine Jousse-Joulin, Nuria Barbarroja, Ignasi Rodríguez-Pintó, Ellen De Langhe, Lorenzo Beretta, Carlo Chizzolini, László Kovács, Torsten Witte, PRECISESADS Clinical Consortium, PRECISESADS Flow Cytometry Consortium, Eléonore Bettacchioli, Anne Buttgereit, Zuzanna Makowska, Ralf Lesche, Maria Orietta Borghi, Javier Martin, Sophie Courtade-Gaiani, Laura Xuereb, Mickaël Guedj, Philippe Moingeon, Marta E. Alarcón-Riquelme, Laurence Laigle, Jacques-Olivier Pers
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Sjögren’s syndrome, a disease that primarily affects women, is poorly understood. Here, the authors combine data from a large cohort of patients and healthy controls to identify biomarkers that distinguish patient subgroups to improve our understa
Externí odkaz:
https://doaj.org/article/fd749685034f43a3afc45a40aaefddd7
Autor:
Emiko Desvaux, Alan Courteau, Pierre-Simon Bellaye, Mélanie Guillemin, Camille Drouet, Paul Walker, Bertrand Collin, Richard A. Decréau
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-6 (2018)
Abstract Purpose Molecular imaging techniques visualise biomarkers for both drug development and personalised medicine. In this field, Cherenkov luminescence imaging (CLI) seems to be very attractive by allowing imaging with clinical PET radiotracers
Externí odkaz:
https://doaj.org/article/26005c11dfde4e85b19e399fcb8ad5f7
Autor:
Emiko Desvaux, Antoine Hamon, Sandra Hubert, Cheïma Boudjeniba, Bastien Chassagnol, Jack Swindle, Audrey Aussy, Laurence Laigle, Jessica Laplume, Perrine Soret, Pierre Jean-François, Isabelle Dupin-Roger, Mickaël Guedj, Philippe Moingeon
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254374 (2021)
While establishing worldwide collective immunity with anti SARS-CoV-2 vaccines, COVID-19 remains a major health issue with dramatic ensuing economic consequences. In the transition, repurposing existing drugs remains the fastest cost-effective approa
Externí odkaz:
https://doaj.org/article/5fd1b6a21aec44c0adf1f01f863bbdaf
Autor:
Fanny Duguet, Céline Ortega-Ferreira, Benjamin Fould, Hélène Darville, Sylvie Berger, Agnès Chomel, Grégory Leclerc, Kai Kisand, Liis Haljasmägi, Adrian C. Hayday, Emiko Desvaux, Emmanuel Nony, Philippe Moingeon, Frédéric De Ceuninck
Publikováno v:
Journal of Translational Autoimmunity, Vol 4, Iss , Pp 100093- (2021)
Increased interferon-α (IFN-α) production is a critical component in the pathophysiology of systemic lupus erythematosus (SLE) and other rheumatic autoimmune diseases. Herein, we report the characterization of S95021, a fully human IgG1 anti–IFN
Externí odkaz:
https://doaj.org/article/5dc19eec2b97490ca0d3a3cdf5238fde
Autor:
Mickaël Guedj, Jack Swindle, Antoine Hamon, Sandra Hubert, Emiko Desvaux, Jessica Laplume, Laura Xuereb, Céline Lefebvre, Yannick Haudry, Christine Gabarroca, Audrey Aussy, Laurence Laigle, Isabelle Dupin-Roger, Philippe Moingeon
Publikováno v:
Expert Opinion on Drug Discovery. 17:815-824
Autor:
Emiko Desvaux, Jacques-Olivier Pers
Publikováno v:
Revue du Rhumatisme Monographies. 89:156-161
Publikováno v:
médecine/sciences. 38:337-339
Publikováno v:
Medecine sciences : M/S. 38(4)
Autor:
Emiko Desvaux, Jacques-Olivier Pers
Publikováno v:
Joint bone spine. 90(2)
Primary Sjögren's syndrome (pSS) is characterized by an autoimmune epithelitis associated with chronic inflammation of the exocrine glands. Alterations of extra-glandular functions in pSS is associated with lymphocytic infiltrates that invade the ep