Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Emi Tatsuda"'
Autor:
Satoshi Yamada, Tadashi Funada, Noriyuki Shibata, Makio Kobayashi, Yoshichika Kawai, Emi Tatsuda, Atsunori Furuhata, Koji Uchida
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 4, Pp 626-634 (2004)
In the present study, to investigate the contribution of n-3 PUFAs in the oxidative modification of protein in vivo, we characterize the covalent binding of 4-hydroxy-2-hexenal (HHE), a potent cytotoxic aldehyde originating from the peroxidation of n
Externí odkaz:
https://doaj.org/article/923ca1d63a9a4f978945da0784cc210c
Autor:
Ayaka Kaku-Fukumoto, Noriko Hino, Hirohiko Hikichi, Dai Nozawa, Jun-ichi Karasawa, Toshio Nakamura, Emi Tatsuda, Shigeyuki Chaki, Yasumitsu Tomishima, Toshiyuki Marumo, Toshiharu Shimazaki, Makiko Kotani, Hiroko Komiyama
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 375:276-285
Histamine H3 receptor antagonists/inverse agonists are known to enhance the activity of histaminergic neurons in the brain, thereby promoting arousal and cognition. Here, we report the in vitro and in vivo pharmacological profiles for a newly synthes
Autor:
Noriko, Hino, Toshiyuki, Marumo, Makiko, Kotani, Toshiharu, Shimazaki, Ayaka, Kaku-Fukumoto, Hirohiko, Hikichi, Jun-Ichi, Karasawa, Yasumitsu, Tomishima, Hiroko, Komiyama, Emi, Tatsuda, Dai, Nozawa, Toshio, Nakamura, Shigeyuki, Chaki
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 375(2)
Histamine H
Autor:
Yusuke Kishi, Yoshihisa Ishii, Takeshi Tsubata, Emi Tatsuda, Tsukasa Matsuda, Kazuyo Toyoda, Nobutaka Hattori, Koji Uchida, Satoru Yamaguchi, Yoshichika Kawai, Takahiro Adachi, Yoshinari Takasaki, Mitsugu Akagawa, Sohei Ito, Takahiro Shibata, Kousuke Ishino
Publikováno v:
Proceedings of the National Academy of Sciences. 103:6160-6165
4-Hydroxy-2-nonenal (HNE), a racemic mixture of 4R- and 4S-enantiomers, is a major product of lipid peroxidation and is believed to be largely responsible for the cytopathological effects observed during oxidative stress. HNE reacts with histidine to
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 62:562-564
4-hydroxy-2-nonenal (HNE), a major racemic product of lipid peroxidation, reacts with histidine to form a stable HNE-histidine Michael addition-type adduct possessing three chiral centres in the cyclic hemiacetal structure. Monoclonal antibodies agai
Publikováno v:
Biochemistry. 42(12)
4-Hydroxy-2-nonenal (HNE), a major lipid peroxidation-derived reactive aldehyde, is a potent inhibitor of sulfhydryl enzymes, such as the glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH). It has been suggested that HNE exerts an inh