Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Emi Kashiwabara"'
Autor:
Yoshimi Kojima, Toru Maruyama, Yukari Fujimoto, Shinsuke Inuki, Emi Kashiwabara, Toshiaki Teratani, Wataru Nakamura, Takanori Kanai, Junichiro Kishi, Toshihiko Aiba, Natsumi Hirata
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
The MHC class I-like molecule CD1d is a nonpolymorphic antigen-presenting glycoprotein, and its ligands include glycolipids, such as α-GalCer. The complexes between CD1d and ligands activate natural killer T cells by T cell receptor recognition, lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5790a04b5961c21f065c45ab9f0dfce
https://doi.org/10.1038/s41598-020-72280-4
https://doi.org/10.1038/s41598-020-72280-4
Autor:
Shinsuke Inuki, Takehiro Suzuki, Yukari Fujimoto, Junichiro Kishi, Emi Kashiwabara, Naoshi Dohmae
Publikováno v:
ACS chemical biology. 15(2)
CD1d is a nonpolymorphic antigen-presenting protein responsible for the regulation of natural killer T (NKT) cell activation. α-Galactosyl ceramide (α-GalCer, KRN7000) is the representative CD1d ligand that can bind to the CD1d protein. The resulti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f169143f7ab07ff783d56264686d161
https://pubmed.ncbi.nlm.nih.gov/31939653
https://pubmed.ncbi.nlm.nih.gov/31939653
Autor:
Etsuko Nabika, Yukari Fujimoto, Junichiro Kishi, Shinsuke Inuki, Natsumi Hirata, Emi Kashiwabara
Publikováno v:
Angewandte Chemie. 130:9803-9807
Th2-biasing CD1d ligands are attractive potential candidates for adjuvants and therapeutic drugs. However, the number of potent ligands is limited, and their biasing mechanism remain unclear. Herein, a series of novel Th2-biasing CD1d glycolipid liga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65c2bdf03f855b96a80cd7ab0c5684a5
https://doi.org/10.1002/ange.201802983
https://doi.org/10.1002/ange.201802983
Autor:
Daisuke Yoshidome, Yukari Fujimoto, Koichi Fukase, Shinsuke Inuki, Emi Kashiwabara, Zenyu Shiokawa
Publikováno v:
ChemMedChem. 11:2682-2689
Indoleamine 2,3-dioxygenase 1 (IDO1) has emerged as a key target for cancer therapy, as IDO1 plays a critical role in the capacity of tumor cells to evade the immune system. The pyrrolopiperazinone alkaloid longamide B and its derivatives were identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21252a0b0ec7ba3b6b6de5559d8f996c
https://doi.org/10.1002/cmdc.201600446
https://doi.org/10.1002/cmdc.201600446
Autor:
Junichiro Kishi, Shinsuke Inuki, Natsumi Hirata, Yukari Fujimoto, Emi Kashiwabara, Daisuke Yoshidome, Osamu Ichihara
Publikováno v:
Bioorganicmedicinal chemistry letters. 29(8)
Abstract CD1d is a non-polymorphic antigen-presenting glycoprotein that recognizes glycolipids as ligands. Ligands bind to the hydrophobic grooves of CD1d, and the resulting ligand-CD1d complexes activate natural killer T (NKT) cells by means of T ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ecb9f291a6d31f17d497d68523cec97
https://pubmed.ncbi.nlm.nih.gov/30824201
https://pubmed.ncbi.nlm.nih.gov/30824201
Publikováno v:
Organic letters. 19(24)
Efficient convergent chemical syntheses of digalactosyl diacylglycerols (DGDGs), which have both a galactose-galactose α(1→6)-linkage and a galactose-glycerol β-linkage along with a diacylglycerol containing various kinds of fatty acids, have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a6657e519c4947459c65f025b299abb
https://pubmed.ncbi.nlm.nih.gov/29182339
https://pubmed.ncbi.nlm.nih.gov/29182339