Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Emetine Hydrochloride"'
Autor:
Richard A. Bryce, Elena Fernández-Álvaro, James A. Wilkinson, Holly Matthews, Priyanka Panwar, Muna Abubaker, Niroshini Nirmalan, Kepa K. Burusco, Andrey Gutnov
Publikováno v:
Antimicrobial Agents and Chemotherapy
Drug repositioning offers an effective alternative to de novo drug design to tackle the urgent need for novel antimalarial treatments. The antiamoebic compound emetine dihydrochloride has been identified as a potent in vitro inhibitor of the multidru
Publikováno v:
Oncology Reports. 31:456-462
Although the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising cancer therapeutic agent, it shows limited efficacy in human pancreatic cancer cells. Protein synthesis inhibition has been reported to sensitize cancer cells
Publikováno v:
Chinese Herbal Medicines. 5:286-291
Objective To control the quality of ipecac and its preparations, and to investigate the simultaneous quantitative determination of cephaeline and emetine. Methods After ultrasonic extraction with acidic methanol solution or direct diluting preparatio
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 3, p e0173303 (2017)
PLoS ONE, Vol 12, Iss 3, p e0173303 (2017)
The widespread introduction of artemisinin-based combination therapy has contributed to\ud recent reductions in malaria mortality. Combination therapies have a range of advantages,\ud including synergism, toxicity reduction, and delaying the onset of
Autor:
Gopal N. Gupta, Emil Bielecki, Kimberly E. Foreman, Maria M. Picken, Samuel White, Alexandra Mitchell
Publikováno v:
Journal of Urology. 195
gemcitabine or mitomycin, significantly increased number of SP cells was found in LGUCC (9.78%), HGUCC (13.56%), MIUCC (20.45%) and bladder cancer cell lines at 24 hours. In NUC only 1.7% SP cells were found and there was no increase in SP cells (Fig
Publikováno v:
Oncology Letters. 2:1309-1312
Exons 3 to 6 in the caspase 9 gene undergo alternative splicing in which the larger caspase 9 splice variant promotes apoptosis, in contrast to the dominant negative anti-apoptotic splice variant, the smaller caspase 9b. In this study, the regulation
Publikováno v:
Journal of Antivirals & Antiretrovirals. :062-071
Dengue fever has become a global concern as dengue infections are prevalent in the tropics and the subtropics, and can lead to a severe life-threatening illness. Currently, there is a widespread interest to search for vaccine or antiviral therapy to
Autor:
Paul C. Kuo, Robert C. Flanigan, Deval Patel, Valerie J. Davidson, Gopal N. Gupta, Kimberly E. Foreman
Publikováno v:
Journal of Urology. 193
Publikováno v:
Journal of AOAC INTERNATIONAL. 86:675-680
A procedure was developed and validated for measuring chlorpheniramine maleate and tincture ipecac (as emetine hydrochloride) by reversed-phase liquid chromatography with methanol–10mM sodium heptanesulfonate (20 + 30) as the mobile phase; the pH w
Publikováno v:
Bladder. 4:e31
OBJECTIVE: We analyzed a novel therapeutic combination of emetine dihydrochloride added to standard of care chemotherapeutic agents (cisplatin, carboplatin, gemcitabine) in human muscle-invasive bladder cancer cell lines to determine if emetine enhan