Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Emese Szekely"'
Publikováno v:
Experimental hematology. 33(8)
Human bone marrow-derived mesenchymal cells (MSCs) are precursors of nonhematopoietic mesenchymal cells of the bone marrow microenvironment. MSCs were shown to inhibit alloreactive T lymphocytes, but the mechanism and mediators of this effect are not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::884df614fba1a5d8e5d88e92b1bf346d
https://pubmed.ncbi.nlm.nih.gov/16038786
https://pubmed.ncbi.nlm.nih.gov/16038786
Autor:
Mary J. Laughlin, Basabi Maitra, James E. Dennis, K Gjini, Stephen E. Haynesworth, Emese Szekely, Omer N. Koc
Publikováno v:
Bone marrow transplantation. 33(6)
Bone marrow-derived mesenchymal stem cells (MSCs) are known to interact with hematopoietic stem cells (HSCs) and immune cells, and represent potential cellular therapy to enhance allogeneic hematopoietic engraftment and prevent graft-versus-host dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17f80c252f78c7d8ded4d9b92663f6a8
https://pubmed.ncbi.nlm.nih.gov/14716336
https://pubmed.ncbi.nlm.nih.gov/14716336
Autor:
Pingfu Fu, Emese Szekely, Kathleen Daum-Woods, Omer N. Koc, Suzanne Kadereit, Linda S. Deeds, M. Kozik, Stephen E. Haynesworth, Mary J. Laughlin, Lisbeth A. Welniak, Glenn W. Goetchius, William J. Murphy
Publikováno v:
Stem cells (Dayton, Ohio). 20(6)
Allogeneic transplantation with umbilical cord blood (UCB) is limited in adult recipients by a low CD34(+) cell dose. Clinical trials incorporating cytokine-based UCB in vitro expansion have not demonstrated significant shortening of hematologic reco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3286ef21f0ac538cb05e885ad1c179e
https://pubmed.ncbi.nlm.nih.gov/12456965
https://pubmed.ncbi.nlm.nih.gov/12456965
Autor:
Hillard M. Lazarus, R. M. Fox, Leila A. Kutteh, Brenda W. Cooper, Stanton L. Gerson, Nancy Tainer, Emese Szekely, Mary J. Laughlin, Omer N. Koc, Howard J. Meyerson
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 18(9)
PURPOSE: Patient response to hematopoietic progenitor-cell mobilizing regimens seems to vary considerably, making comparison between regimens difficult. To eliminate this inter-patient variability, we designed a cross-over trial and prospectively com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e070ae2818c7153e61b6aaf8b449a8
https://pubmed.ncbi.nlm.nih.gov/10944143
https://pubmed.ncbi.nlm.nih.gov/10944143
Publikováno v:
Cancer gene therapy. 6(4)
Human hematopoietic progenitors express low levels of O6-alkylguanine-DNA alkyltransferase and are sensitive to 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), particularly following O6-benzylguanine (BG)-mediated O6-alkylguanine-DNA alkyltransferase in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7a909b2fa59d8831805378cac5a12b8
https://pubmed.ncbi.nlm.nih.gov/10419052
https://pubmed.ncbi.nlm.nih.gov/10419052
Publikováno v:
Blood. 108:2564-2564
Human mesenchymal stem cells (MSCs) produce soluble factors that inhibit T-cell proliferation and alloreactivity. We have previously shown that MSCs require activation by CD14+ monocytes in cell culture. Toll-like receptors (TLRs) critically modulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eccc03ed6aee61fc09571a0554eff6c9
https://doi.org/10.1182/blood.v108.11.2564.2564
https://doi.org/10.1182/blood.v108.11.2564.2564
Autor:
Omer N. Koc, Emese Szekely, Stanton L. Gerson, Colin L. Sweeney, Margaret Groh, Basabi Maitra
Publikováno v:
Blood. 106:3049-3049
Over-expression of the pro-survival Akt gene in rat mesenchymal stem cells (MSCs) by retroviral transduction has been shown to improve cardiac repair following MSC transplant into infarcted rat heart (Mangi et al., Nature Medicine, 2003), and may hol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97afdbe02fd704a11600621869eab6a0
https://doi.org/10.1182/blood.v106.11.3049.3049
https://doi.org/10.1182/blood.v106.11.3049.3049
Autor:
J. Banks, Emese Szekely, Mary J. Laughlin, M. Kozik, Marcie R. Finney, Y. Huang, L.R. Fanning
Publikováno v:
Blood. 106:2303-2303
Background. Umbilical cord blood (UCB), a source of hematopoeitic stem cells (HSC), is marked by delayed engraftment attributed to the limited cellular content of a single UCB unit. Cytokine-based ex vivo expansion of UCB is a way of increasing the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c52fb818896927062678b03939793e6
https://doi.org/10.1182/blood.v106.11.2303.2303
https://doi.org/10.1182/blood.v106.11.2303.2303
Publikováno v:
Blood. 106:1394-1394
Human mesenchymal stem cells (MSCs) suppress T-cell activation and proliferation by inducible expression and secretion of soluble inhibitory factors. We have previously shown that MSCs require activation by antigen-presenting cells (APCs) to secrete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6e430d998e48722e9bb53eef942176a
https://doi.org/10.1182/blood.v106.11.1394.1394
https://doi.org/10.1182/blood.v106.11.1394.1394
Autor:
M. Kozik, Stephen E. Haynesworth, J. Banks, Omer N. Koc, Mary J. Laughlin, L.R. Fanning, Emese Szekely, Kathleen Daum-Woods, Marcie R. Finney, O. Masri, Y. Huang
Publikováno v:
Blood. 104:2846-2846
Cytokine-based expansion of umbilical cord blood (UCB) in vitro prior to infusion has been pursued in an attempt to overcome the limited cellular content of a single UCB unit. Thus far, these attempts have not shown improvement in kinetics of donor-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4286a7d349a7d033fafe9edddbaaf73e
https://doi.org/10.1182/blood.v104.11.2846.2846
https://doi.org/10.1182/blood.v104.11.2846.2846