Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Emerson Lucena, da Silva"'
Autor:
Julio Paulino Daniel, Felipe Pantoja Mesquita, Emerson Lucena Da Silva, Pedro Filho Noronha de Souza, Luina Benevides Lima, Lais Lacerda Brasil de Oliveira, Maria Elisabete Amaral de Moraes, Caroline de Fátima Aquino Moreira-Nunes, Rommel Mario Rodríguez Burbano, Geancarlo Zanatta, Raquel Carvalho Montenegro
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Chronic myeloid leukemia (CML) is caused by constitutively active fusion protein BCR-ABL1, and targeting ABL1 is a promising therapy option. Imatinib, dasatinib, and nilotinib have all been shown to work effectively in clinical trials. ABL1 mutations
Externí odkaz:
https://doaj.org/article/486df2451ce54331aa7dcd637d9d8492
Autor:
Felipe Pantoja Mesquita, Pedro Filho Noronha Souza, Emerson Lucena da Silva, Luina Benevides Lima, Lais Lacerda Brasil de Oliveira, Caroline Aquino Moreira-Nunes, William J. Zuercher, Rommel Mario Rodríguez Burbano, Maria Elisabete Amaral de Moraes, Raquel Carvalho Montenegro
Publikováno v:
Pharmaceutics, Vol 14, Iss 9, p 1841 (2022)
Despite advances in cancer chemotherapy, gastric cancer (GC) continues to have high recurrence rates and poor prognosis with limited treatment options. Understanding the etiology of GC and developing more effective, less harmful therapeutic approache
Externí odkaz:
https://doaj.org/article/e549895150a8478daf46fd0fec513f01
Autor:
Caio Bezerra Machado, Flávia Melo Cunha de Pinho Pessoa, Emerson Lucena da Silva, Laudreísa da Costa Pantoja, Rodrigo Monteiro Ribeiro, Manoel Odorico de Moraes Filho, Maria Elisabete Amaral de Moraes, Raquel Carvalho Montenegro, Rommel Mário Rodriguez Burbano, André Salim Khayat, Caroline Aquino Moreira-Nunes
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1604 (2021)
Cancer is still a major barrier to life expectancy increase worldwide, and hematologic neoplasms represent a relevant percentage of cancer incidence rates. Tumor dependence of continuous proliferative signals mediated through protein kinases overexpr
Externí odkaz:
https://doaj.org/article/02c9551f195f4cee92efdae133b64a29
Autor:
Luina Benevides Lima, Caroline de Fátima Aquino Moreira-Nunes, Felipe Pantoja Mesquita, Lais Lacerda Brasil De Oliveira, Emanuel Cintra Austregésilo Bezerra, Emerson Lucena Da Silva, Fernando Barroso Duarte, Acy Telles de Souza Quixadá, Maria Elisabete Amaral De Moraes, Raquel Carvalho Montenegro
Publikováno v:
Brazilian Journal of Case Reports. 2:47-53
Chronic Myeloid Leukemia (CML) is characterized by the increased and unregulated growth of myeloid cells in bone marrow and accumulation of these cells in blood. Its occurrence during pregnancy is a very rare condition and the correct management is n
Autor:
Felipe Pantoja Mesquita, Pedro Filho Noronha Souza, Dyane Rocha Aragão, Expedito Maia Diógenes, Emerson Lucena da Silva, Jackson Lima Amaral, Valder Nogueira Freire, Débora de Souza Collares Maia Castelo-Branco, Raquel Carvalho Montenegro
Publikováno v:
Future Virology.
Aim: This study aimed to analyze the phylogenetic relationships between the ACE2 of humans and other animals and investigate the potential interaction between SARS-CoV-2 RBD and ACE2 of different species. Materials & methods: The phylogenetic constru
Publikováno v:
Handbook of Cancer and Immunology ISBN: 9783030809621
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eda9d06c5fd0a85b666d8f5b3fcef669
https://doi.org/10.1007/978-3-030-80962-1_103-1
https://doi.org/10.1007/978-3-030-80962-1_103-1
Autor:
Emerson Lucena da Silva, Felipe Pantoja Mesquita, Ingryd Nayara de Farias Ramos, Carinne Borges de Souza Moraes Rego Gomes, Caroline dos Santos Moreira, Vítor Francisco Ferreira, David Rodrigues da Rocha, Marcelo de Oliveira Bahia, Caroline Aquino Moreira-Nunes, Carolina Rosal Teixeira de Souza, Rommel Mario Rodrigues Burbano, Raquel Carvalho Montenegro
Publikováno v:
Toxicology and applied pharmacology. 456
Colorectal cancer (CRC) is estimated as the third most incident cancer and second in mortality worldwide. Moreover, CRC metastasis reduces patients' survival rates. Thus, the study and identification of new compounds with anticancer activity selectiv
Autor:
Adrhyann Jullyanne, de Sousa Portilho, Emerson Lucena, da Silva, Emanuel Cintra Austregésilo, Bezerra, Carinne Borges de Souza, Moraes Rego Gomes, Vitor, Ferreira, Maria Elisabete Amaral, de Moraes, David Rodrigues, da Rocha, Rommel Mário Rodriguez, Burbano, Caroline Aquino, Moreira-Nunes, Raquel Carvalho, Montenegro
Publikováno v:
International journal of molecular sciences. 23(15)
The multidrug resistance (MDR) phenotype is one of the major obstacles in the treatment of chronic myeloid leukemia (CML) in advantage stages such as blast crisis. In this scenario, more patients develop resistance mechanisms during the course of the
Autor:
Caroline Aquino Moreira-Nunes, Emerson Lucena da Silva, Maria Elisabete Amaral de Moraes, Manoel Odorico de Moraes Filho, Caio Bezerra Machado
Publikováno v:
Anticancer Research. 40:3055-3063
The idea of utilizing poly-ADP-ribose polymerase inhibitors (PARPi) as therapeutics for cancer has grown in popularity since its original approval for clinical usage in treatment of BRCA DNA repair-associated-mutated ovarian cancer. In this study, we
Autor:
Flávia Melo Cunha de Pinho Pessoa, Caio Bezerra Machado, Emerson Lucena da Silva, Laudreísa da Costa Pantoja, Rodrigo Monteiro Ribeiro, Maria Elisabete Amaral de Moraes, Manoel Odorico de Moraes Filho, Raquel Carvalho Montenegro, André Salim Khayat, Caroline Aquino Moreira-Nunes
Publikováno v:
International journal of molecular sciences. 23(7)
The increasing numbers of cancer cases worldwide and the exceedingly high mortality rates of some tumor subtypes raise the question about if the current protocols for cancer management are effective and what has been done to improve upon oncologic pa