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pro vyhledávání: '"Emerson G. Moreira"'
Autor:
Anna Carolina Dias Paixão, Renata Serrano Lopes, Irina Nastassja Riediger, A Bernardes, Anderson Brandao Leite, Filipe Zimmer Dezordi, Tiago Gräf, Cliomar Alves dos Santos, George Silva, Lidio Gonçalves Lima Neto, Ricardo Khouri, Matheus V. F. Ferraz, Cristiano Fernandes da Costa, Gabriel Luz Wallau, Luciana Appolinario, Felicidade Mota Pereira, Sandra Fernandes, Maria do Carmo Debur, Marilda M. Siqueira, Adriano Abbud, Edson Delatorre, Emerson G. Moreira, Alice Sampaio Barreto da Rocha, Claudio Tavares Sacchi, Victor Costa de Souza, Gonzalo Bello, Paola Cristina Resende, Valdinete Alves do Nascimento, Fernando Couto Motta, Tirza Mattos, Felipe Gomes Naveca, Darcita Buerger Rovaris, Ana Carolina da Fonseca Mendonça, Fabiano Vieira da Silva, Fernanda Nascimento, Danilo F. Coêlho, Roberto D. Lins
Publikováno v:
Virus Evolution
Mutations at both the receptor-binding domain (RBD) and the amino (N)-terminal domain (NTD) of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike (S) glycoprotein can alter its antigenicity and promote immune escape. We identified
Autor:
Emerson G. Moreira, Matheus V. F. Ferraz, Danilo F. Coêlho, Gabriel Luz Wallau, Roberto D. Lins
Publikováno v:
Chemical communications (Cambridge, England). 57(49)
SARS-CoV-2 VOC immune evasion is mainly due to lower cross-reactivity from previously elicited class I/II neutralizing antibodies, while increased affinity to hACE2 plays a minor role. The affinity between antibodies and VOCs is impacted by remodelin