Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Emerson F. Harkin"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15620 (2023)
Serotonin 1A (5-HT1A) autoreceptors located on serotonin neurons inhibit their activity, and their upregulation has been implicated in depression, suicide and resistance to antidepressant treatment. Conversely, post-synaptic 5-HT1A heteroreceptors ar
Externí odkaz:
https://doaj.org/article/f202ea3e1c1444ebac44bbbce9dfb772
Publikováno v:
eLife, Vol 11 (2022)
The primary motor cortex (M1) is known to be a critical site for movement initiation and motor learning. Surprisingly, it has also been shown to possess reward-related activity, presumably to facilitate reward-based learning of new movements. However
Externí odkaz:
https://doaj.org/article/d6b4725e21bf4859a49eb10928f86a35
Publikováno v:
Neuroscience. 489:200-215
Neurons are very complicated computational devices, incorporating numerous non-linear processes, particularly in their dendrites. Biophysical models capture these processes directly by explicitly modelling physiological variables, such as ion channel
Autor:
Emerson F Harkin, Michael B Lynn, Alexandre Payeur, Jean-François Boucher, Léa Caya-Bissonnette, Dominic Cyr, Chloe Stewart, André Longtin, Richard Naud, Jean-Claude Béïque
Publikováno v:
eLife. 12
By means of an expansive innervation, the serotonin (5-HT) neurons of the dorsal raphe nucleus (DRN) are positioned to enact coordinated modulation of circuits distributed across the entire brain in order to adaptively regulate behavior. Yet the netw
Autor:
Emerson F Harkin, Michael B Lynn, Alexandre Payeur, Jean-François Boucher, Léa Caya-Bissonnette, Dominic Cyr, Chloe Stewart, André Longtin, Richard Naud, Jean-Claude Béïque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d886cf26b2782c174091effcda00892
https://doi.org/10.7554/elife.72951.sa2
https://doi.org/10.7554/elife.72951.sa2
Publikováno v:
Advances in experimental medicine and biology. 1359
The generalized integrate-and-fire (GIF) neuron model accounts for some of the most fundamental behaviours of neurons within a compact and extensible mathematical framework. Here, we introduce the main concepts behind the design of the GIF model in t
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030894382
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b4708d71d4806b6b36d3f523b13ecb3
https://doi.org/10.1007/978-3-030-89439-9_3
https://doi.org/10.1007/978-3-030-89439-9_3
The primary motor cortex (M1) is known to be a critical site for movement initiation and motor learning. Surprisingly, it has also been shown to possess reward-related activity, presumably to facilitate reward-based learning of new movements. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d71be753cb1d2fd5b3c27b96bece6c8
https://doi.org/10.1101/2021.08.08.455571
https://doi.org/10.1101/2021.08.08.455571
Publikováno v:
eLife, Vol 11 (2022)
The primary motor cortex (M1) is known to be a critical site for movement initiation and motor learning. Surprisingly, it has also been shown to possess reward-related activity, presumably to facilitate reward-based learning of new movements. However