Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Emerson F, Harkin"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15620 (2023)
Serotonin 1A (5-HT1A) autoreceptors located on serotonin neurons inhibit their activity, and their upregulation has been implicated in depression, suicide and resistance to antidepressant treatment. Conversely, post-synaptic 5-HT1A heteroreceptors ar
Externí odkaz:
https://doaj.org/article/f202ea3e1c1444ebac44bbbce9dfb772
Autor:
Emerson F Harkin, Michael B Lynn, Alexandre Payeur, Jean-François Boucher, Léa Caya-Bissonnette, Dominic Cyr, Chloe Stewart, André Longtin, Richard Naud, Jean-Claude Béïque
Publikováno v:
eLife, Vol 12 (2023)
By means of an expansive innervation, the serotonin (5-HT) neurons of the dorsal raphe nucleus (DRN) are positioned to enact coordinated modulation of circuits distributed across the entire brain in order to adaptively regulate behavior. Yet the netw
Externí odkaz:
https://doaj.org/article/20b69314e853484c8e8cab4b250de1de
Publikováno v:
eLife, Vol 11 (2022)
The primary motor cortex (M1) is known to be a critical site for movement initiation and motor learning. Surprisingly, it has also been shown to possess reward-related activity, presumably to facilitate reward-based learning of new movements. However
Externí odkaz:
https://doaj.org/article/d6b4725e21bf4859a49eb10928f86a35
Publikováno v:
Neuroscience. 489:200-215
Neurons are very complicated computational devices, incorporating numerous non-linear processes, particularly in their dendrites. Biophysical models capture these processes directly by explicitly modelling physiological variables, such as ion channel
Autor:
Emerson F Harkin, Michael B Lynn, Alexandre Payeur, Jean-François Boucher, Léa Caya-Bissonnette, Dominic Cyr, Chloe Stewart, André Longtin, Richard Naud, Jean-Claude Béïque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d886cf26b2782c174091effcda00892
https://doi.org/10.7554/elife.72951.sa2
https://doi.org/10.7554/elife.72951.sa2
Publikováno v:
Advances in experimental medicine and biology. 1359
The generalized integrate-and-fire (GIF) neuron model accounts for some of the most fundamental behaviours of neurons within a compact and extensible mathematical framework. Here, we introduce the main concepts behind the design of the GIF model in t
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030894382
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b4708d71d4806b6b36d3f523b13ecb3
https://doi.org/10.1007/978-3-030-89439-9_3
https://doi.org/10.1007/978-3-030-89439-9_3
The primary motor cortex (M1) is known to be a critical site for movement initiation and motor learning. Surprisingly, it has also been shown to possess reward-related activity, presumably to facilitate reward-based learning of new movements. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d71be753cb1d2fd5b3c27b96bece6c8
https://doi.org/10.1101/2021.08.08.455571
https://doi.org/10.1101/2021.08.08.455571
Publikováno v:
eLife, Vol 11 (2022)
The primary motor cortex (M1) is known to be a critical site for movement initiation and motor learning. Surprisingly, it has also been shown to possess reward-related activity, presumably to facilitate reward-based learning of new movements. However